ENSG00000171791

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000333681 ENSG00000171791 No_inf pgKDN_inf BCL2 protein_coding protein_coding 12.63468 16.48029 12.51957 0.2849533 0.1677063 -0.3962803 1.467629 0.0000000 2.3372614 0.00000000 0.8328677 7.8748347 0.1394167 0.000000 0.187125 0.187125 0.0002785949 0.0002785949 FALSE TRUE
ENST00000398117 ENSG00000171791 No_inf pgKDN_inf BCL2 protein_coding protein_coding 12.63468 16.48029 12.51957 0.2849533 0.1677063 -0.3962803 2.768151 3.8712859 2.5654031 0.35317129 0.7061243 -0.5917365 0.2189500 0.235200 0.203875 -0.031325 0.8919289567 0.0002785949 FALSE TRUE
ENST00000589955 ENSG00000171791 No_inf pgKDN_inf BCL2 protein_coding protein_coding 12.63468 16.48029 12.51957 0.2849533 0.1677063 -0.3962803 0.670646 0.8036821 0.6158694 0.07001413 0.1021094 -0.3786037 0.0547500 0.048825 0.049525 0.000700 1.0000000000 0.0002785949 FALSE TRUE
ENST00000677635 ENSG00000171791 No_inf pgKDN_inf BCL2 protein_coding protein_coding_CDS_not_defined 12.63468 16.48029 12.51957 0.2849533 0.1677063 -0.3962803 7.249728 11.3293488 6.6368457 0.50159597 0.5098279 -0.7705960 0.5460333 0.687175 0.530400 -0.156775 0.4195841659 0.0002785949 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171791 E001 351.2258105 0.0001216588 1.990708e-05 0.0006159889 18 63123346 63127776 4431 - 2.515 2.552 0.123
ENSG00000171791 E002 25.5991754 0.0024794385 6.854071e-01 0.8700270352 18 63127777 63128211 435 - 1.430 1.406 -0.084
ENSG00000171791 E003 26.6018910 0.0005194584 3.354842e-02 0.1742682751 18 63128212 63128759 548 - 1.500 1.381 -0.410
ENSG00000171791 E004 0.0000000       18 63138263 63138411 149 -      
ENSG00000171791 E005 0.1176306 0.0117747287 3.756762e-01   18 63158073 63158238 166 - 0.111 0.000 -9.025
ENSG00000171791 E006 0.0000000       18 63161846 63161869 24 -      
ENSG00000171791 E007 0.6087413 0.0144499361 4.056795e-01 0.6883724401 18 63280887 63281214 328 - 0.273 0.150 -1.088
ENSG00000171791 E008 0.8627966 0.0127174069 9.354240e-01 0.9814730346 18 63301662 63301865 204 - 0.273 0.261 -0.088
ENSG00000171791 E009 14.4397657 0.0054571234 8.116686e-01 0.9307027880 18 63313802 63317529 3728 - 1.167 1.187 0.071
ENSG00000171791 E010 2.4630207 0.0755153441 9.367623e-01 0.9819564845 18 63317530 63318081 552 - 0.523 0.540 0.082
ENSG00000171791 E011 29.6018407 0.0005514541 1.019082e-03 0.0152168307 18 63318082 63318952 871 - 1.573 1.399 -0.599
ENSG00000171791 E012 5.9098756 0.0029045353 7.394989e-01 0.8967965972 18 63318953 63319173 221 - 0.852 0.816 -0.141
ENSG00000171791 E013 15.5294668 0.0009452874 1.570196e-02 0.1084340069 18 63319174 63320128 955 - 1.306 1.132 -0.617

Help

Please Click HERE to learn more details about the results from DEXseq.