ENSG00000171793

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000463423 ENSG00000171793 No_inf pgKDN_inf CTPS1 protein_coding nonsense_mediated_decay 172.4024 74.20656 220.749 1.380863 6.720891 1.572659 4.438272 13.314817 0.00000 2.5237990 0.000000 -10.379900 0.05929167 0.177875 0.000000 -0.177875 1.268996e-21 9.983688e-33 FALSE TRUE
ENST00000464283 ENSG00000171793 No_inf pgKDN_inf CTPS1 protein_coding protein_coding_CDS_not_defined 172.4024 74.20656 220.749 1.380863 6.720891 1.572659 34.648639 0.000000 56.25591 0.0000000 8.574642 12.458045 0.15509167 0.000000 0.252025 0.252025 9.983688e-33 9.983688e-33 FALSE FALSE
ENST00000470271 ENSG00000171793 No_inf pgKDN_inf CTPS1 protein_coding protein_coding 172.4024 74.20656 220.749 1.380863 6.720891 1.572659 9.455481 5.062409 10.37603 0.6623336 1.094028 1.033902 0.05780000 0.067950 0.047250 -0.020700 7.256364e-01 9.983688e-33 FALSE TRUE
ENST00000650070 ENSG00000171793 No_inf pgKDN_inf CTPS1 protein_coding protein_coding 172.4024 74.20656 220.749 1.380863 6.720891 1.572659 81.968557 32.532847 103.69370 2.4148873 8.991691 1.672055 0.46680000 0.437675 0.468875 0.031200 8.568383e-01 9.983688e-33 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171793 E001 1.8058425 0.0331943461 6.918123e-01 8.738016e-01 1 40979300 40979687 388 + 0.452 0.387 -0.352
ENSG00000171793 E002 2.0240490 0.0277094428 6.492790e-02 2.567290e-01 1 40979688 40979695 8 + 0.544 0.235 -1.800
ENSG00000171793 E003 3.0999822 0.0240877140 7.235078e-02 2.728597e-01 1 40979696 40979704 9 + 0.669 0.387 -1.352
ENSG00000171793 E004 3.0999822 0.0240877140 7.235078e-02 2.728597e-01 1 40979705 40979705 1 + 0.669 0.387 -1.352
ENSG00000171793 E005 5.3783893 0.0052391161 3.874407e-02 1.904583e-01 1 40979706 40979720 15 + 0.856 0.588 -1.102
ENSG00000171793 E006 11.3537493 0.0216294138 9.959443e-03 8.002318e-02 1 40979721 40979740 20 + 1.146 0.852 -1.090
ENSG00000171793 E007 15.9928668 0.0244902397 2.219956e-01 5.092557e-01 1 40979741 40979754 14 + 1.243 1.121 -0.434
ENSG00000171793 E008 15.3952587 0.0111816186 1.939601e-01 4.737705e-01 1 40979755 40979756 2 + 1.226 1.109 -0.418
ENSG00000171793 E009 32.3412957 0.0033539496 5.494465e-01 7.941938e-01 1 40979757 40979829 73 + 1.510 1.473 -0.126
ENSG00000171793 E010 15.2723157 0.0028260383 1.972671e-01 4.785286e-01 1 40980055 40980561 507 + 1.152 1.252 0.358
ENSG00000171793 E011 1.5702881 0.0102318309 9.436459e-01 9.844026e-01 1 40980585 40980885 301 + 0.398 0.387 -0.063
ENSG00000171793 E012 2.1741496 0.0611705699 8.849169e-01 9.612634e-01 1 40980886 40981043 158 + 0.477 0.499 0.107
ENSG00000171793 E013 1.9762137 0.0077533116 1.276525e-02 9.411910e-02 1 40981044 40981229 186 + 0.301 0.662 1.844
ENSG00000171793 E014 0.1271363 0.0124191950 2.328693e-01   1 40981646 40981664 19 + 0.000 0.133 11.705
ENSG00000171793 E015 1.1259103 0.0141765221 5.095785e-03 5.032706e-02 1 40981665 40981926 262 + 0.125 0.546 2.914
ENSG00000171793 E016 0.6075454 0.0285384959 6.998911e-01 8.776315e-01 1 40981927 40981994 68 + 0.176 0.235 0.522
ENSG00000171793 E017 0.2362687 0.0157147323 6.509012e-01   1 40982040 40982111 72 + 0.125 0.000 -12.085
ENSG00000171793 E018 0.2441403 0.0166122896 5.489666e-01   1 40983161 40983277 117 + 0.067 0.133 1.107
ENSG00000171793 E019 98.3311115 0.0001647974 1.670734e-03 2.221084e-02 1 40983278 40983456 179 + 2.004 1.899 -0.351
ENSG00000171793 E020 114.9672447 0.0058823019 1.417253e-01 4.005506e-01 1 40984821 40984991 171 + 2.059 1.996 -0.212
ENSG00000171793 E021 80.1068215 0.0001968978 2.581281e-01 5.504026e-01 1 40987372 40987472 101 + 1.897 1.856 -0.138
ENSG00000171793 E022 0.1186381 0.0119219699 1.000000e+00   1 40988519 40988593 75 + 0.067 0.000 -11.165
ENSG00000171793 E023 94.1484451 0.0003716685 2.746294e-01 5.681520e-01 1 40988594 40988710 117 + 1.941 1.977 0.121
ENSG00000171793 E024 62.2812911 0.0002628111 4.633946e-01 7.333050e-01 1 40991165 40991248 84 + 1.766 1.795 0.099
ENSG00000171793 E025 59.7705880 0.0002437059 7.077594e-01 8.814181e-01 1 40991765 40991845 81 + 1.764 1.748 -0.054
ENSG00000171793 E026 3.4907503 0.0042761295 3.480202e-06 1.371054e-04 1 40993853 40995916 2064 + 0.336 0.932 2.692
ENSG00000171793 E027 55.5211132 0.0047816024 5.180441e-01 7.733224e-01 1 40995917 40995978 62 + 1.738 1.704 -0.116
ENSG00000171793 E028 74.0720180 0.0021280851 3.698292e-01 6.580788e-01 1 40995979 40996068 90 + 1.863 1.824 -0.129
ENSG00000171793 E029 24.7387018 0.0006388156 1.276610e-01 3.787901e-01 1 40996069 40997393 1325 + 1.352 1.446 0.325
ENSG00000171793 E030 105.7903460 0.0001761014 1.434170e-01 4.032989e-01 1 40997394 40997526 133 + 2.018 1.972 -0.156
ENSG00000171793 E031 7.4640148 0.0128898190 8.907057e-03 7.443341e-02 1 40999830 41000434 605 + 0.790 1.071 1.060
ENSG00000171793 E032 2.2059670 0.0152518279 1.188793e-01 3.643804e-01 1 41000435 41000566 132 + 0.398 0.627 1.107
ENSG00000171793 E033 7.1013226 0.0990113920 4.333715e-02 2.029963e-01 1 41000567 41000972 406 + 0.766 1.058 1.107
ENSG00000171793 E034 1.8873747 0.0090921394 1.288072e-05 4.241201e-04 1 41000973 41001028 56 + 0.125 0.754 3.807
ENSG00000171793 E035 82.9484315 0.0002331969 5.249573e-01 7.778609e-01 1 41001029 41001117 89 + 1.906 1.883 -0.077
ENSG00000171793 E036 0.2352613 0.2622147427 7.211050e-01   1 41001539 41001584 46 + 0.125 0.000 -11.036
ENSG00000171793 E037 88.3595736 0.0001696114 4.716181e-01 7.389748e-01 1 41002160 41002254 95 + 1.934 1.909 -0.084
ENSG00000171793 E038 96.5930720 0.0001530278 1.264066e-01 3.768691e-01 1 41003114 41003176 63 + 1.980 1.930 -0.170
ENSG00000171793 E039 0.4909842 0.5012540441 5.529298e-01   1 41003981 41004250 270 + 0.125 0.235 1.105
ENSG00000171793 E040 84.2085730 0.0023465372 2.672435e-02 1.516254e-01 1 41006051 41006094 44 + 1.933 1.843 -0.305
ENSG00000171793 E041 51.2644872 0.0028033616 3.090840e-01 6.024407e-01 1 41007449 41007455 7 + 1.709 1.658 -0.173
ENSG00000171793 E042 106.5002679 0.0018063733 1.781678e-01 4.529443e-01 1 41007456 41007545 90 + 2.021 1.973 -0.162
ENSG00000171793 E043 104.5324761 0.0004046029 5.409682e-01 7.887541e-01 1 41008659 41008714 56 + 2.005 1.985 -0.067
ENSG00000171793 E044 10.6911014 0.0014224847 1.142623e-01 3.560358e-01 1 41008715 41008770 56 + 0.993 1.133 0.508
ENSG00000171793 E045 7.3185068 0.0018873960 3.331562e-02 1.734989e-01 1 41008771 41008793 23 + 0.813 1.029 0.817
ENSG00000171793 E046 147.1494783 0.0001109865 3.683041e-01 6.567804e-01 1 41008794 41008890 97 + 2.153 2.129 -0.080
ENSG00000171793 E047 173.4701992 0.0001152934 1.947955e-01 4.747877e-01 1 41009445 41009589 145 + 2.206 2.236 0.102
ENSG00000171793 E048 8.1577471 0.0034294485 5.203170e-02 2.264954e-01 1 41009590 41010160 571 + 0.866 1.058 0.717
ENSG00000171793 E049 121.3366688 0.0012027165 3.989649e-02 1.935922e-01 1 41010161 41010254 94 + 2.040 2.104 0.216
ENSG00000171793 E050 34.7585416 0.0004051803 7.971745e-28 4.018207e-25 1 41010255 41011657 1403 + 1.256 1.815 1.918
ENSG00000171793 E051 540.6666045 0.0004018006 2.364472e-01 5.254313e-01 1 41011658 41012565 908 + 2.703 2.719 0.055

Help

Please Click HERE to learn more details about the results from DEXseq.