ENSG00000171928

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000307767 ENSG00000171928 No_inf pgKDN_inf TVP23B protein_coding protein_coding 20.41141 13.60248 22.00487 0.3661096 1.268852 0.6935487 5.3409735 0.7283499 8.671269 0.7283499 5.477141 3.5555293 0.25150833 0.056775 0.3758 0.319025 0.86029619 0.02002033 FALSE TRUE
ENST00000572845 ENSG00000171928 No_inf pgKDN_inf TVP23B protein_coding retained_intron 20.41141 13.60248 22.00487 0.3661096 1.268852 0.6935487 0.2656403 0.7969209 0.000000 0.2689432 0.000000 -6.3343554 0.01936667 0.058100 0.0000 -0.058100 0.05279255 0.02002033   FALSE
ENST00000581733 ENSG00000171928 No_inf pgKDN_inf TVP23B protein_coding protein_coding 20.41141 13.60248 22.00487 0.3661096 1.268852 0.6935487 11.1504529 9.0729770 12.586031 0.6151152 4.883837 0.4717321 0.57001667 0.667850 0.5888 -0.079050 1.00000000 0.02002033 FALSE FALSE
ENST00000582288 ENSG00000171928 No_inf pgKDN_inf TVP23B protein_coding retained_intron 20.41141 13.60248 22.00487 0.3661096 1.268852 0.6935487 2.6624804 1.9138860 0.000000 0.7052771 0.000000 -7.5878795 0.10718333 0.137100 0.0000 -0.137100 0.02002033 0.02002033   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171928 E001 0.0000000       17 18781111 18781142 32 +      
ENSG00000171928 E002 0.0000000       17 18781143 18781154 12 +      
ENSG00000171928 E003 0.0000000       17 18781155 18781179 25 +      
ENSG00000171928 E004 0.0000000       17 18781180 18781182 3 +      
ENSG00000171928 E005 0.2363338 0.0160622942 0.383448031   17 18781183 18781286 104 + 0.149 0.000 -10.422
ENSG00000171928 E006 0.1187032 0.0121335791 0.756739900   17 18781287 18781305 19 + 0.081 0.000 -11.497
ENSG00000171928 E007 0.7619709 0.1683496657 0.007908759 0.06859939 17 18781314 18782549 1236 + 0.000 0.441 13.306
ENSG00000171928 E008 0.0000000       17 18789035 18789051 17 +      
ENSG00000171928 E009 0.1187032 0.0121335791 0.756739900   17 18789353 18789357 5 + 0.081 0.000 -11.497
ENSG00000171928 E010 0.1187032 0.0121335791 0.756739900   17 18789358 18789362 5 + 0.081 0.000 -11.497
ENSG00000171928 E011 0.9703857 0.0149476205 0.819067683 0.93413056 17 18789363 18789435 73 + 0.306 0.274 -0.214
ENSG00000171928 E012 0.1271363 0.0125189397 0.377921168   17 18789436 18789669 234 + 0.000 0.112 11.290
ENSG00000171928 E013 2.4485392 0.0057523268 0.436591818 0.71302564 17 18790896 18790960 65 + 0.483 0.595 0.523
ENSG00000171928 E014 3.1463348 0.0045941011 0.470558226 0.73821482 17 18790961 18791040 80 + 0.650 0.561 -0.395
ENSG00000171928 E015 1.7242072 0.0085197782 0.237594649 0.52656270 17 18795806 18797578 1773 + 0.347 0.525 0.938
ENSG00000171928 E016 1.4319125 0.0097478213 0.065236720 0.25714224 17 18797579 18797668 90 + 0.483 0.201 -1.799
ENSG00000171928 E017 7.4424093 0.0020699654 0.454381931 0.72705535 17 18798812 18798943 132 + 0.889 0.965 0.286
ENSG00000171928 E018 0.3723465 0.0172504793 0.391583950   17 18798944 18799131 188 + 0.081 0.201 1.523
ENSG00000171928 E019 5.4661283 0.0029179335 0.840932629 0.94297613 17 18804138 18804266 129 + 0.814 0.798 -0.062
ENSG00000171928 E020 0.0000000       17 18804267 18804616 350 +      
ENSG00000171928 E021 33.0542712 0.0005276743 0.486519110 0.75012421 17 18805541 18806714 1174 + 1.535 1.518 -0.058

Help

Please Click HERE to learn more details about the results from DEXseq.