ENSG00000171940

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000302342 ENSG00000171940 No_inf pgKDN_inf ZNF217 protein_coding protein_coding 48.42228 57.29557 50.08226 1.202141 0.6970723 -0.1940877 38.999538 45.558629 40.1910845 2.9334841 2.0632306 -0.18080655 0.80706667 0.793400 0.801750 0.008350 0.99365615 0.0471867 FALSE  
ENST00000371471 ENSG00000171940 No_inf pgKDN_inf ZNF217 protein_coding protein_coding 48.42228 57.29557 50.08226 1.202141 0.6970723 -0.1940877 3.368170 4.220137 4.0679795 0.5807074 1.0252003 -0.05284988 0.06779167 0.073875 0.081775 0.007900 1.00000000 0.0471867 FALSE  
MSTRG.18422.1 ENSG00000171940 No_inf pgKDN_inf ZNF217 protein_coding   48.42228 57.29557 50.08226 1.202141 0.6970723 -0.1940877 3.076628 6.065250 0.8277506 1.1108787 0.8277506 -2.85835100 0.06099167 0.106500 0.016575 -0.089925 0.04718670 0.0471867 FALSE  
MSTRG.18422.2 ENSG00000171940 No_inf pgKDN_inf ZNF217 protein_coding   48.42228 57.29557 50.08226 1.202141 0.6970723 -0.1940877 1.377137 0.000000 2.5772348 0.0000000 1.2942214 8.01526716 0.03093333 0.000000 0.050775 0.050775 0.05181092 0.0471867 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000171940 E001 0.0000000       20 53567065 53567070 6 -      
ENSG00000171940 E002 0.8606891 1.283501e-02 9.638204e-01 9.923511e-01 20 53567071 53567072 2 - 0.263 0.270 0.051
ENSG00000171940 E003 1.2328444 1.012215e-02 8.147591e-01 9.323561e-01 20 53567073 53567081 9 - 0.324 0.361 0.221
ENSG00000171940 E004 2.2056241 5.038023e-02 6.376843e-01 8.454664e-01 20 53567082 53567099 18 - 0.544 0.469 -0.364
ENSG00000171940 E005 743.6694015 5.498420e-05 2.058410e-07 1.119136e-05 20 53567100 53568819 1720 - 2.840 2.884 0.148
ENSG00000171940 E006 137.6609928 1.014854e-03 9.033887e-01 9.690196e-01 20 53568820 53569264 445 - 2.134 2.138 0.012
ENSG00000171940 E007 37.4566471 3.946115e-04 4.419209e-01 7.172683e-01 20 53571721 53571853 133 - 1.601 1.564 -0.127
ENSG00000171940 E008 379.9539817 8.395704e-05 3.690493e-02 1.849622e-01 20 53575727 53577280 1554 - 2.592 2.563 -0.096
ENSG00000171940 E009 35.7310043 3.989251e-04 3.581603e-01 6.476570e-01 20 53578334 53578450 117 - 1.585 1.540 -0.155
ENSG00000171940 E010 178.1532197 9.798441e-05 2.824006e-04 5.524480e-03 20 53581461 53582541 1081 - 2.291 2.213 -0.262
ENSG00000171940 E011 59.1509940 2.566164e-04 1.584060e-01 4.253920e-01 20 53582542 53582924 383 - 1.804 1.750 -0.184
ENSG00000171940 E012 29.2399248 6.950155e-03 4.413826e-01 7.168613e-01 20 53582925 53583168 244 - 1.503 1.453 -0.170
ENSG00000171940 E013 0.2454921 1.626166e-02 8.441408e-01   20 53583767 53583819 53 - 0.106 0.085 -0.364
ENSG00000171940 E014 0.6358076 3.748979e-01 1.303449e-01 3.829806e-01 20 53586752 53586943 192 - 0.000 0.318 11.073
ENSG00000171940 E015 1.2249431 2.186890e-02 6.959752e-01 8.760029e-01 20 53592878 53592961 84 - 0.378 0.318 -0.364
ENSG00000171940 E016 6.1555997 5.203696e-03 9.670706e-01 9.933727e-01 20 53593756 53594106 351 - 0.852 0.848 -0.016
ENSG00000171940 E017 2.7294395 5.345701e-03 2.594794e-01 5.519744e-01 20 53594107 53594263 157 - 0.469 0.627 0.736
ENSG00000171940 E018 0.1170040 1.167886e-02 4.163709e-01   20 53597631 53597703 73 - 0.106 0.000 -11.049
ENSG00000171940 E019 0.0000000       20 53608354 53608444 91 -      
ENSG00000171940 E020 0.3617709 1.643763e-02 4.390357e-01   20 53608832 53608892 61 - 0.192 0.085 -1.364
ENSG00000171940 E021 0.0000000       20 53609748 53609907 160 -      

Help

Please Click HERE to learn more details about the results from DEXseq.