ENSG00000172053

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000306125 ENSG00000172053 No_inf pgKDN_inf QARS1 protein_coding protein_coding 97.95291 100.5693 92.33625 7.899019 1.794063 -0.1232087 29.027359 22.324150 36.6064939 0.9790806 1.7106763 0.7132423 0.30080000 0.225925 0.397425 0.171500 0.01287701 0.01287701 FALSE TRUE
ENST00000453392 ENSG00000172053 No_inf pgKDN_inf QARS1 protein_coding protein_coding 97.95291 100.5693 92.33625 7.899019 1.794063 -0.1232087 7.295134 4.951743 5.5513700 4.1481521 3.9469442 0.1645933 0.07120833 0.041400 0.058800 0.017400 1.00000000 0.01287701 FALSE TRUE
ENST00000464962 ENSG00000172053 No_inf pgKDN_inf QARS1 protein_coding protein_coding 97.95291 100.5693 92.33625 7.899019 1.794063 -0.1232087 30.358326 30.585905 27.1429786 2.1573616 0.8036193 -0.1722281 0.31230000 0.310600 0.294600 -0.016000 0.95885683 0.01287701 FALSE TRUE
ENST00000494984 ENSG00000172053 No_inf pgKDN_inf QARS1 protein_coding retained_intron 97.95291 100.5693 92.33625 7.899019 1.794063 -0.1232087 3.828127 8.830682 0.8156932 3.5278462 0.5093485 -3.4204799 0.03758333 0.085400 0.008600 -0.076800 0.39825121 0.01287701   FALSE
ENST00000637281 ENSG00000172053 No_inf pgKDN_inf QARS1 protein_coding nonsense_mediated_decay 97.95291 100.5693 92.33625 7.899019 1.794063 -0.1232087 8.216612 5.601787 9.9542662 1.9383845 3.2535936 0.8283033 0.08627500 0.060525 0.108400 0.047875 0.82452906 0.01287701 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172053 E001 0.2374063 0.2377043770 2.853230e-01   3 49095932 49095932 1 - 0.175 0.000 -11.615
ENSG00000172053 E002 0.2374063 0.2377043770 2.853230e-01   3 49095933 49095933 1 - 0.175 0.000 -11.644
ENSG00000172053 E003 0.4812643 0.0236216002 3.099061e-01   3 49095934 49095935 2 - 0.241 0.094 -1.620
ENSG00000172053 E004 2.9237526 0.0048677944 3.854568e-01 0.6714650205 3 49095936 49095936 1 - 0.650 0.534 -0.521
ENSG00000172053 E005 3.1672636 0.0043716295 4.015406e-01 0.6846711354 3 49095937 49095938 2 - 0.674 0.563 -0.483
ENSG00000172053 E006 3.4120305 0.0040939515 4.161262e-01 0.6960042374 3 49095939 49095940 2 - 0.696 0.591 -0.450
ENSG00000172053 E007 5.1323664 0.0027309717 6.996743e-01 0.8776072368 3 49095941 49095947 7 - 0.810 0.766 -0.173
ENSG00000172053 E008 8.7020002 0.0025688054 8.065143e-01 0.9284838897 3 49095948 49095953 6 - 0.974 0.998 0.087
ENSG00000172053 E009 9.2004131 0.0027890133 6.481590e-01 0.8514252789 3 49095954 49095960 7 - 0.986 1.028 0.157
ENSG00000172053 E010 14.1075349 0.0010666615 6.080612e-01 0.8292157958 3 49095961 49095993 33 - 1.158 1.197 0.141
ENSG00000172053 E011 46.2441851 0.0003498173 4.638305e-01 0.7335494000 3 49095994 49096079 86 - 1.657 1.689 0.110
ENSG00000172053 E012 1.1342225 0.0103430858 1.541763e-02 0.1071288594 3 49097110 49097133 24 - 0.096 0.468 2.965
ENSG00000172053 E013 3.4517219 0.0068737859 2.948917e-01 0.5881790973 3 49097134 49097287 154 - 0.571 0.708 0.593
ENSG00000172053 E014 42.0149266 0.0003355600 1.657957e-01 0.4356862660 3 49097992 49098034 43 - 1.598 1.663 0.219
ENSG00000172053 E015 55.9469026 0.0003027236 7.046111e-04 0.0114024001 3 49098035 49098092 58 - 1.677 1.815 0.465
ENSG00000172053 E016 35.9049286 0.0051603532 3.727578e-03 0.0404188140 3 49098093 49098093 1 - 1.470 1.639 0.579
ENSG00000172053 E017 46.9752781 0.0003409874 7.144025e-04 0.0115257512 3 49098094 49098117 24 - 1.596 1.745 0.509
ENSG00000172053 E018 2.3466736 0.0117440926 2.850850e-01 0.5787835242 3 49098118 49098191 74 - 0.437 0.591 0.742
ENSG00000172053 E019 68.8542259 0.0003520140 5.692127e-04 0.0096570988 3 49098192 49098251 60 - 1.773 1.900 0.428
ENSG00000172053 E020 36.0957996 0.0004176877 3.443595e-01 0.6356589574 3 49098252 49098258 7 - 1.543 1.591 0.161
ENSG00000172053 E021 3.3815154 0.1285363777 2.118720e-02 0.1316638064 3 49098259 49098352 94 - 0.350 0.801 2.103
ENSG00000172053 E022 42.6308027 0.0080163500 2.785449e-01 0.5717489276 3 49098353 49098372 20 - 1.604 1.669 0.223
ENSG00000172053 E023 84.5973872 0.0011497541 1.314824e-01 0.3846480505 3 49098373 49098480 108 - 1.903 1.956 0.179
ENSG00000172053 E024 1.1245595 0.0841027101 1.258379e-01 0.3761121103 3 49098481 49098549 69 - 0.175 0.430 1.772
ENSG00000172053 E025 0.7441571 0.0138886928 4.315972e-01 0.7093248404 3 49098550 49098599 50 - 0.175 0.294 0.965
ENSG00000172053 E026 65.7043426 0.0002189210 3.492276e-01 0.6395992970 3 49098600 49098692 93 - 1.841 1.807 -0.116
ENSG00000172053 E027 5.3693747 0.0027689531 5.104906e-04 0.0088815477 3 49098693 49098884 192 - 0.541 0.953 1.687
ENSG00000172053 E028 76.2062126 0.0001899483 2.484091e-01 0.5392771985 3 49098885 49098974 90 - 1.907 1.868 -0.133
ENSG00000172053 E029 44.4687550 0.0003672167 1.671922e-01 0.4377139256 3 49098975 49098989 15 - 1.689 1.627 -0.210
ENSG00000172053 E030 99.5729478 0.0021414835 1.166561e-02 0.0889165134 3 49099110 49099239 130 - 2.046 1.958 -0.297
ENSG00000172053 E031 39.5938744 0.0003743273 2.236989e-01 0.5112623923 3 49099240 49099253 14 - 1.637 1.580 -0.196
ENSG00000172053 E032 0.3622142 0.0164954577 5.684842e-01   3 49099330 49099343 14 - 0.175 0.094 -1.035
ENSG00000172053 E033 48.1957389 0.0013389631 4.177745e-01 0.6975496568 3 49099344 49099402 59 - 1.710 1.674 -0.123
ENSG00000172053 E034 39.0530754 0.0003589417 6.975543e-01 0.8765786032 3 49099403 49099431 29 - 1.612 1.593 -0.062
ENSG00000172053 E035 59.5994696 0.0002300454 6.523866e-01 0.8535275716 3 49099510 49099589 80 - 1.773 1.790 0.060
ENSG00000172053 E036 43.3080955 0.0034256966 6.743505e-01 0.8650359462 3 49099590 49099647 58 - 1.635 1.656 0.071
ENSG00000172053 E037 69.6418448 0.0128106174 5.901404e-01 0.8185956025 3 49099761 49099853 93 - 1.866 1.832 -0.112
ENSG00000172053 E038 0.7352509 0.0134371575 9.756520e-01 0.9957486014 3 49099854 49099960 107 - 0.241 0.237 -0.035
ENSG00000172053 E039 49.0966412 0.0030708026 6.656282e-01 0.8609310616 3 49099961 49099993 33 - 1.710 1.689 -0.071
ENSG00000172053 E040 76.6493494 0.0001983017 5.419280e-01 0.7893578411 3 49099994 49100083 90 - 1.878 1.900 0.071
ENSG00000172053 E041 32.5879128 0.0007001219 9.360090e-01 0.9816863605 3 49100084 49100091 8 - 1.528 1.524 -0.014
ENSG00000172053 E042 1.4792528 0.0537826798 6.238073e-01 0.8380934668 3 49100092 49100189 98 - 0.350 0.430 0.450
ENSG00000172053 E043 31.0090349 0.0005186256 9.091253e-01 0.9711944545 3 49100190 49100198 9 - 1.501 1.508 0.022
ENSG00000172053 E044 42.8148248 0.0012898857 5.168576e-01 0.7725376191 3 49100199 49100240 42 - 1.625 1.656 0.105
ENSG00000172053 E045 44.7006427 0.0025653488 3.018518e-01 0.5950972519 3 49100241 49100298 58 - 1.632 1.683 0.171
ENSG00000172053 E046 48.6142304 0.0002947881 7.660567e-01 0.9090917638 3 49100380 49100458 79 - 1.702 1.689 -0.042
ENSG00000172053 E047 27.4025027 0.0054062806 6.767716e-01 0.8659957797 3 49100575 49100588 14 - 1.466 1.441 -0.087
ENSG00000172053 E048 31.8337986 0.0020427425 9.401382e-01 0.9830356734 3 49100589 49100607 19 - 1.518 1.514 -0.013
ENSG00000172053 E049 30.1770082 0.0155876281 5.315191e-01 0.7821388364 3 49100608 49100630 23 - 1.518 1.470 -0.163
ENSG00000172053 E050 33.0675008 0.0006234808 9.702498e-01 0.9939872347 3 49100631 49100659 29 - 1.531 1.533 0.008
ENSG00000172053 E051 31.6910935 0.0004573003 6.118426e-01 0.8310654921 3 49100660 49100674 15 - 1.528 1.501 -0.091
ENSG00000172053 E052 0.0000000       3 49100675 49100740 66 -      
ENSG00000172053 E053 33.0209288 0.0004837996 4.199145e-01 0.6993451275 3 49101355 49101378 24 - 1.553 1.511 -0.142
ENSG00000172053 E054 45.2888350 0.0003109272 5.820645e-01 0.8138722833 3 49101379 49101441 63 - 1.677 1.653 -0.082
ENSG00000172053 E055 26.1973886 0.0005185297 7.509973e-01 0.9017941865 3 49101620 49101626 7 - 1.443 1.425 -0.062
ENSG00000172053 E056 47.1847226 0.0003084233 2.473277e-01 0.5379420931 3 49101627 49101685 59 - 1.708 1.658 -0.170
ENSG00000172053 E057 31.6549758 0.0004400804 3.164426e-01 0.6093838616 3 49101686 49101705 20 - 1.540 1.488 -0.180
ENSG00000172053 E058 42.6547052 0.0013530552 2.725442e-01 0.5662336275 3 49101828 49101863 36 - 1.666 1.614 -0.176
ENSG00000172053 E059 33.1011763 0.0004275987 1.411534e-01 0.3997336223 3 49101864 49101883 20 - 1.570 1.494 -0.259
ENSG00000172053 E060 30.8071619 0.0004752222 2.835644e-01 0.5773409985 3 49101884 49101887 4 - 1.531 1.474 -0.196
ENSG00000172053 E061 33.8767074 0.0005762583 3.280321e-01 0.6205136264 3 49101888 49101899 12 - 1.567 1.517 -0.171
ENSG00000172053 E062 44.0654718 0.0003265938 5.121128e-01 0.7691995064 3 49102205 49102251 47 - 1.668 1.639 -0.099
ENSG00000172053 E063 26.4572408 0.0026546450 7.623050e-01 0.9072585480 3 49102252 49102262 11 - 1.447 1.429 -0.062
ENSG00000172053 E064 21.9096686 0.0031147470 6.103352e-01 0.8306661689 3 49102263 49102265 3 - 1.377 1.343 -0.116
ENSG00000172053 E065 20.8110767 0.0051701423 6.700738e-01 0.8629934852 3 49102419 49102419 1 - 1.353 1.324 -0.103
ENSG00000172053 E066 35.0539716 0.0058510073 1.582459e-01 0.4251898965 3 49102420 49102448 29 - 1.598 1.514 -0.287
ENSG00000172053 E067 33.4877977 0.0004547028 1.994085e-01 0.4810364691 3 49102449 49102472 24 - 1.570 1.504 -0.225
ENSG00000172053 E068 0.0000000       3 49102595 49102606 12 -      
ENSG00000172053 E069 0.0000000       3 49102607 49102665 59 -      
ENSG00000172053 E070 0.0000000       3 49102666 49102687 22 -      
ENSG00000172053 E071 0.0000000       3 49102688 49102702 15 -      
ENSG00000172053 E072 0.1187032 0.0118208930 5.253197e-01   3 49102703 49102732 30 - 0.096 0.000 -10.643
ENSG00000172053 E073 0.3638483 0.0165870701 5.685832e-01   3 49103333 49103344 12 - 0.175 0.094 -1.035
ENSG00000172053 E074 33.8972059 0.0004162638 4.578485e-01 0.7297379749 3 49103345 49103376 32 - 1.561 1.524 -0.129
ENSG00000172053 E075 34.8675382 0.0006074171 4.647993e-01 0.7342418787 3 49103377 49103409 33 - 1.534 1.571 0.127
ENSG00000172053 E076 2.7697165 0.0801949368 3.295398e-03 0.0370974749 3 49103410 49103431 22 - 0.241 0.748 2.628
ENSG00000172053 E077 3.5384529 0.0850917708 8.756227e-05 0.0021311297 3 49103432 49103466 35 - 0.175 0.863 3.666
ENSG00000172053 E078 2.5216439 0.0336827989 4.178993e-04 0.0075863285 3 49103467 49103476 10 - 0.175 0.729 3.135
ENSG00000172053 E079 2.5216439 0.0336827989 4.178993e-04 0.0075863285 3 49103477 49103477 1 - 0.175 0.729 3.135
ENSG00000172053 E080 4.4005240 0.0058458208 1.813988e-05 0.0005681512 3 49103478 49103555 78 - 0.350 0.917 2.550
ENSG00000172053 E081 2.8752933 0.0049455642 6.917891e-03 0.0625996704 3 49103556 49103630 75 - 0.350 0.729 1.813
ENSG00000172053 E082 24.3249206 0.0028561796 3.614009e-01 0.6508366774 3 49103631 49103664 34 - 1.372 1.429 0.198
ENSG00000172053 E083 28.0707215 0.0066793002 9.848234e-01 0.9989950641 3 49103665 49103706 42 - 1.462 1.463 0.002
ENSG00000172053 E084 0.0000000       3 49103707 49103862 156 -      
ENSG00000172053 E085 20.1345965 0.0008081004 1.428140e-01 0.4022629378 3 49103863 49103880 18 - 1.372 1.276 -0.334
ENSG00000172053 E086 39.1831241 0.0032008593 9.656191e-02 0.3235509496 3 49103881 49103972 92 - 1.647 1.560 -0.297
ENSG00000172053 E087 0.7440310 0.0139763036 4.321538e-01 0.7096079127 3 49103973 49104014 42 - 0.175 0.294 0.965
ENSG00000172053 E088 0.3722815 0.0165317588 5.994304e-01   3 49104015 49104098 84 - 0.096 0.171 0.965
ENSG00000172053 E089 0.6154116 0.2080199525 7.032066e-01 0.8792148316 3 49104099 49104323 225 - 0.175 0.237 0.550
ENSG00000172053 E090 25.3278626 0.0067258715 6.384027e-01 0.8459440034 3 49104324 49104356 33 - 1.436 1.405 -0.105
ENSG00000172053 E091 18.5967117 0.0186354029 7.127162e-01 0.8839530301 3 49104357 49104372 16 - 1.308 1.276 -0.111
ENSG00000172053 E092 27.3662701 0.0005731084 2.662390e-01 0.5597526541 3 49104373 49104465 93 - 1.484 1.421 -0.216
ENSG00000172053 E093 10.2373268 0.0012898085 1.586734e-01 0.4257538864 3 49104466 49104471 6 - 1.110 0.987 -0.450
ENSG00000172053 E094 0.3628435 0.0165646955 5.682484e-01   3 49104472 49104532 61 - 0.175 0.094 -1.035
ENSG00000172053 E095 14.3731918 0.0013660632 7.775575e-02 0.2853424791 3 49104617 49104652 36 - 1.252 1.117 -0.479
ENSG00000172053 E096 22.3459116 0.0006153766 1.577809e-01 0.4245112606 3 49104653 49104698 46 - 1.411 1.324 -0.304
ENSG00000172053 E097 17.8455736 0.0007579519 3.329073e-01 0.6249708029 3 49104699 49104908 210 - 1.308 1.242 -0.233
ENSG00000172053 E098 0.2441403 0.0162424512 9.841744e-01   3 49104909 49105004 96 - 0.096 0.094 -0.035
ENSG00000172053 E099 0.2441403 0.0162424512 9.841744e-01   3 49105005 49105130 126 - 0.096 0.094 -0.035

Help

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