ENSG00000172071

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000303236 ENSG00000172071 No_inf pgKDN_inf EIF2AK3 protein_coding protein_coding 9.887632 7.77232 11.76162 0.1928136 0.9515543 0.5970412 1.1962514 0.3411039 1.9053819 0.20122723 0.2973941 2.447662 0.11548333 0.044300 0.159450 0.115150 0.35023052 0.02201975 FALSE TRUE
ENST00000652736 ENSG00000172071 No_inf pgKDN_inf EIF2AK3 protein_coding protein_coding_CDS_not_defined 9.887632 7.77232 11.76162 0.1928136 0.9515543 0.5970412 0.8223965 0.0000000 0.0000000 0.00000000 0.0000000 0.000000 0.08400833 0.000000 0.000000 0.000000   0.02201975 FALSE TRUE
ENST00000668866 ENSG00000172071 No_inf pgKDN_inf EIF2AK3 protein_coding protein_coding_CDS_not_defined 9.887632 7.77232 11.76162 0.1928136 0.9515543 0.5970412 0.2327497 0.5921667 0.0000000 0.09919635 0.0000000 -5.912091 0.02935000 0.076825 0.000000 -0.076825 0.02201975 0.02201975   FALSE
ENST00000682103 ENSG00000172071 No_inf pgKDN_inf EIF2AK3 protein_coding nonsense_mediated_decay 9.887632 7.77232 11.76162 0.1928136 0.9515543 0.5970412 2.4691462 2.5481369 3.0069243 0.87551804 1.8448521 0.237985 0.25692500 0.331625 0.242250 -0.089375 0.83405099 0.02201975 TRUE TRUE
ENST00000682276 ENSG00000172071 No_inf pgKDN_inf EIF2AK3 protein_coding protein_coding_CDS_not_defined 9.887632 7.77232 11.76162 0.1928136 0.9515543 0.5970412 0.4340925 1.3022775 0.0000000 0.47998335 0.0000000 -7.035929 0.05625833 0.168775 0.000000 -0.168775 0.03777372 0.02201975 FALSE TRUE
ENST00000682603 ENSG00000172071 No_inf pgKDN_inf EIF2AK3 protein_coding protein_coding 9.887632 7.77232 11.76162 0.1928136 0.9515543 0.5970412 1.8992219 0.6372318 2.5550013 0.63723176 1.5379974 1.986605 0.17601667 0.079100 0.223950 0.144850 0.82818222 0.02201975 FALSE TRUE
ENST00000684455 ENSG00000172071 No_inf pgKDN_inf EIF2AK3 protein_coding nonsense_mediated_decay 9.887632 7.77232 11.76162 0.1928136 0.9515543 0.5970412 1.1274833 1.0772558 2.3051943 0.76950742 0.7818065 1.090442 0.11056667 0.137275 0.194425 0.057150 0.83286760 0.02201975 FALSE TRUE
MSTRG.16650.7 ENSG00000172071 No_inf pgKDN_inf EIF2AK3 protein_coding   9.887632 7.77232 11.76162 0.1928136 0.9515543 0.5970412 0.6371460 0.1293265 0.8128559 0.12932647 0.4744233 2.562171 0.05888333 0.016000 0.079575 0.063575 0.82573363 0.02201975 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172071 E001 0.0000000       2 88556741 88556745 5 -      
ENSG00000172071 E002 0.0000000       2 88556746 88556764 19 -      
ENSG00000172071 E003 0.0000000       2 88556765 88556768 4 -      
ENSG00000172071 E004 0.1271363 0.012314189 0.4205405079   2 88556769 88556809 41 - 0.000 0.108 10.077
ENSG00000172071 E005 5.3784334 0.003425461 0.6097261310 0.83017695 2 88556810 88556930 121 - 0.771 0.839 0.268
ENSG00000172071 E006 3.7930632 0.003908925 0.6112703861 0.83087050 2 88556931 88556934 4 - 0.644 0.717 0.306
ENSG00000172071 E007 3.9106939 0.003798669 0.7292347365 0.89201094 2 88556935 88556940 6 - 0.665 0.717 0.219
ENSG00000172071 E008 47.2020115 0.000335086 0.1369203072 0.39389054 2 88556941 88557853 913 - 1.699 1.657 -0.143
ENSG00000172071 E009 6.4833786 0.002535076 0.4455004044 0.71988551 2 88557854 88557936 83 - 0.830 0.919 0.345
ENSG00000172071 E010 0.2459004 0.016669644 0.8480933077   2 88557937 88558916 980 - 0.084 0.108 0.399
ENSG00000172071 E011 5.0459561 0.003537935 0.1164284754 0.35987469 2 88558917 88558979 63 - 0.685 0.873 0.753
ENSG00000172071 E012 1.9893049 0.087492276 0.0929583552 0.31671533 2 88558980 88561336 2357 - 0.315 0.612 1.537
ENSG00000172071 E013 3.3198383 0.106165801 0.3690820118 0.65744387 2 88562289 88562344 56 - 0.551 0.717 0.722
ENSG00000172071 E014 3.4424375 0.028930637 0.2024429453 0.48485980 2 88562345 88562390 46 - 0.551 0.740 0.815
ENSG00000172071 E015 3.3613955 0.094409817 0.0292527292 0.16050272 2 88562391 88565361 2971 - 0.432 0.802 1.647
ENSG00000172071 E016 0.3635961 0.016543142 0.7482418180   2 88570017 88570873 857 - 0.154 0.108 -0.601
ENSG00000172071 E017 5.2658337 0.024384909 0.3737022630 0.66143535 2 88570874 88570919 46 - 0.738 0.856 0.466
ENSG00000172071 E018 5.4530676 0.002752691 0.2561629317 0.54827618 2 88570920 88571041 122 - 0.856 0.740 -0.459
ENSG00000172071 E019 0.0000000       2 88571042 88571396 355 -      
ENSG00000172071 E020 0.0000000       2 88574666 88575077 412 -      
ENSG00000172071 E021 0.0000000       2 88575078 88575360 283 -      
ENSG00000172071 E022 0.0000000       2 88575361 88575446 86 -      
ENSG00000172071 E023 3.2257392 0.027760241 0.0159340068 0.10947179 2 88576554 88576703 150 - 0.432 0.782 1.569
ENSG00000172071 E024 4.5256083 0.003514385 0.5622102556 0.80212379 2 88579518 88579640 123 - 0.703 0.782 0.321
ENSG00000172071 E025 1.2015003 0.092366323 0.1529726758 0.41727001 2 88579641 88581581 1941 - 0.432 0.194 -1.602
ENSG00000172071 E026 4.0008166 0.003598264 0.3828887352 0.66907049 2 88583430 88583542 113 - 0.738 0.641 -0.408
ENSG00000172071 E027 6.1532319 0.058222091 0.1422385241 0.40122869 2 88585841 88586061 221 - 0.927 0.740 -0.729
ENSG00000172071 E028 3.6536866 0.054807603 0.8970276929 0.96607104 2 88587982 88588104 123 - 0.665 0.668 0.012
ENSG00000172071 E029 2.2976274 0.087286989 0.3939938070 0.67881744 2 88588761 88588832 72 - 0.577 0.429 -0.717
ENSG00000172071 E030 2.8880271 0.005059877 0.0564057324 0.23689353 2 88588833 88588891 59 - 0.685 0.429 -1.186
ENSG00000172071 E031 1.4339289 0.008794274 0.0461589453 0.21074550 2 88588892 88588901 10 - 0.496 0.194 -1.923
ENSG00000172071 E032 4.0023897 0.003587043 0.3827869464 0.66897480 2 88590443 88590605 163 - 0.738 0.641 -0.408
ENSG00000172071 E033 3.5449281 0.004221772 0.6327828110 0.84277753 2 88590818 88591008 191 - 0.623 0.693 0.300
ENSG00000172071 E034 1.1144584 0.010866302 0.1718382009 0.44448704 2 88591009 88591052 44 - 0.215 0.429 1.399
ENSG00000172071 E035 0.0000000       2 88593017 88593114 98 -      
ENSG00000172071 E036 3.7117094 0.003704078 0.0039988240 0.04242183 2 88593272 88593405 134 - 0.801 0.429 -1.660
ENSG00000172071 E037 0.0000000       2 88593406 88593912 507 -      
ENSG00000172071 E038 0.2372762 0.335063750 0.4149510434   2 88593913 88594108 196 - 0.154 0.000 -13.140
ENSG00000172071 E039 0.0000000       2 88594109 88595229 1121 -      
ENSG00000172071 E040 2.7604191 0.008939185 0.0278226894 0.15577587 2 88595469 88595619 151 - 0.685 0.381 -1.449
ENSG00000172071 E041 0.3560444 0.025448629 0.1616066210   2 88595620 88595663 44 - 0.215 0.000 -13.904
ENSG00000172071 E042 0.0000000       2 88595751 88595857 107 -      
ENSG00000172071 E043 1.4392767 0.366152510 0.1869834303 0.46486099 2 88613724 88613853 130 - 0.496 0.194 -1.926
ENSG00000172071 E044 0.0000000       2 88624746 88624929 184 -      
ENSG00000172071 E045 1.3205090 0.239686948 0.1978104635 0.47927124 2 88626967 88627024 58 - 0.466 0.194 -1.773
ENSG00000172071 E046 1.3152258 0.009412418 0.0730033854 0.27454226 2 88627025 88627148 124 - 0.465 0.194 -1.771
ENSG00000172071 E047 1.7882715 0.007807801 0.0112300991 0.08680095 2 88627149 88627464 316 - 0.576 0.194 -2.301
ENSG00000172071 E048 0.8700348 0.013880132 0.1439975039 0.40409180 2 88685170 88686997 1828 - 0.154 0.381 1.721
ENSG00000172071 E049 0.0000000       2 88686998 88687006 9 -      
ENSG00000172071 E050 0.3801504 0.028331946 0.0654874705   2 88687007 88687526 520 - 0.000 0.266 13.844
ENSG00000172071 E051 0.3812526 0.015963446 0.0640768088   2 88687527 88688144 618 - 0.000 0.266 13.858
ENSG00000172071 E052 0.2458395 0.016239479 0.8482351428   2 88688145 88688308 164 - 0.084 0.108 0.399
ENSG00000172071 E053 1.7610932 0.008443261 0.0012358707 0.01762439 2 88690177 88690754 578 - 0.154 0.641 2.984
ENSG00000172071 E054 0.9963522 0.115575298 0.1102175991 0.34839735 2 88690755 88691175 421 - 0.154 0.429 1.983
ENSG00000172071 E055 1.0151109 0.011693053 0.0006862756 0.01117223 2 88691176 88691315 140 - 0.000 0.512 14.987
ENSG00000172071 E056 0.5081066 0.016048141 0.0247714609 0.14466962 2 88691316 88691318 3 - 0.000 0.327 14.200
ENSG00000172071 E057 0.6254549 0.192287044 0.1500400389 0.41248206 2 88691319 88691395 77 - 0.084 0.327 2.399
ENSG00000172071 E058 0.4892516 0.032394792 0.8049125252   2 88691396 88691437 42 - 0.154 0.194 0.399
ENSG00000172071 E059 0.3716209 0.016547956 0.4427092152   2 88691438 88691442 5 - 0.084 0.194 1.399
ENSG00000172071 E060 0.2447669 0.016132167 0.8476399684   2 88691443 88691518 76 - 0.084 0.108 0.399

Help

Please Click HERE to learn more details about the results from DEXseq.