ENSG00000172164

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000395601 ENSG00000172164 No_inf pgKDN_inf SNTB1 protein_coding protein_coding 37.96915 60.95481 31.29976 1.273634 0.4623551 -0.9613644 3.356564 8.180950 1.4650433 1.639662 0.8586905 -2.4732736 0.06621667 0.13295 0.04635 -0.08660 0.4163799976 0.0003326859 FALSE TRUE
ENST00000517992 ENSG00000172164 No_inf pgKDN_inf SNTB1 protein_coding protein_coding 37.96915 60.95481 31.29976 1.273634 0.4623551 -0.9613644 28.838205 39.953057 26.9788967 2.769554 0.4272526 -0.5663009 0.80704167 0.65350 0.86195 0.20845 0.0003326859 0.0003326859 FALSE TRUE
MSTRG.28154.1 ENSG00000172164 No_inf pgKDN_inf SNTB1 protein_coding   37.96915 60.95481 31.29976 1.273634 0.4623551 -0.9613644 2.299911 5.529025 0.7691238 0.861292 0.3167798 -2.8297075 0.04758333 0.09100 0.02445 -0.06655 0.1585635839 0.0003326859 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172164 E001 1.7409822 7.776004e-03 0.886979245 0.96219354 8 120535537 120535744 208 - 0.395 0.417 0.119
ENSG00000172164 E002 0.7619374 2.014425e-02 0.094475403 0.31986418 8 120535745 120535755 11 - 0.000 0.294 10.656
ENSG00000172164 E003 9.8461494 2.561171e-02 0.415654137 0.69578643 8 120535756 120535846 91 - 0.926 1.022 0.358
ENSG00000172164 E004 778.1866943 5.632886e-05 0.005833665 0.05530548 8 120535847 120538969 3123 - 2.835 2.854 0.063
ENSG00000172164 E005 16.9548767 2.730090e-03 0.253417069 0.54496170 8 120541810 120542000 191 - 1.275 1.186 -0.312
ENSG00000172164 E006 44.8299989 8.300266e-03 0.164480180 0.43377214 8 120548762 120548958 197 - 1.676 1.594 -0.279
ENSG00000172164 E007 1.8881024 6.368170e-02 0.164362564 0.43363743 8 120551131 120551251 121 - 0.241 0.491 1.498
ENSG00000172164 E008 6.1231290 2.229791e-03 0.221119873 0.50818785 8 120570259 120571210 952 - 0.706 0.853 0.586
ENSG00000172164 E009 4.8396771 1.832496e-02 0.948229762 0.98654009 8 120571211 120571364 154 - 0.737 0.729 -0.032
ENSG00000172164 E010 55.8339625 2.668918e-04 0.377027305 0.66414239 8 120575086 120575225 140 - 1.739 1.701 -0.130
ENSG00000172164 E011 52.8187290 3.294224e-04 0.176371248 0.45046920 8 120632444 120632609 166 - 1.730 1.670 -0.203
ENSG00000172164 E012 23.6228903 6.583905e-04 0.799336640 0.92470950 8 120632610 120632651 42 - 1.338 1.354 0.056
ENSG00000172164 E013 0.0000000       8 120654879 120655033 155 -      
ENSG00000172164 E014 62.9894214 3.044544e-04 0.942983580 0.98416852 8 120693692 120693908 217 - 1.762 1.764 0.008
ENSG00000172164 E015 82.4424851 1.906941e-04 0.115701012 0.35861263 8 120811273 120811758 486 - 1.917 1.862 -0.186
ENSG00000172164 E016 31.7071274 1.010948e-02 0.184748494 0.46211685 8 120811759 120812069 311 - 1.537 1.444 -0.320
ENSG00000172164 E017 0.0000000       8 120812426 120812477 52 -      
ENSG00000172164 E018 0.0000000       8 120812605 120813084 480 -      
ENSG00000172164 E019 0.0000000       8 120813085 120813273 189 -      

Help

Please Click HERE to learn more details about the results from DEXseq.