ENSG00000172273

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000350777 ENSG00000172273 No_inf pgKDN_inf HINFP protein_coding protein_coding 16.93091 20.01525 15.21397 0.3183334 0.5168873 -0.3954757 3.0918769 5.400613 2.5962423 0.6908535 1.5893858 -1.0538208 0.17318333 0.271575 0.171900 -0.099675 0.64972735 0.04262302 FALSE  
ENST00000527206 ENSG00000172273 No_inf pgKDN_inf HINFP protein_coding retained_intron 16.93091 20.01525 15.21397 0.3183334 0.5168873 -0.3954757 0.5957747 1.442132 0.1671725 0.2237632 0.1671725 -3.0349459 0.03135833 0.072175 0.010125 -0.062050 0.13647099 0.04262302 FALSE  
ENST00000527410 ENSG00000172273 No_inf pgKDN_inf HINFP protein_coding protein_coding 16.93091 20.01525 15.21397 0.3183334 0.5168873 -0.3954757 0.3837675 0.000000 1.1513025 0.0000000 0.4020356 6.8596000 0.02450833 0.000000 0.073525 0.073525 0.04262302 0.04262302 FALSE  
ENST00000529354 ENSG00000172273 No_inf pgKDN_inf HINFP protein_coding retained_intron 16.93091 20.01525 15.21397 0.3183334 0.5168873 -0.3954757 2.0371373 2.195292 1.9870406 0.4091465 0.5065152 -0.1431061 0.12296667 0.109725 0.133100 0.023375 0.92701958 0.04262302 FALSE  
ENST00000530678 ENSG00000172273 No_inf pgKDN_inf HINFP protein_coding protein_coding 16.93091 20.01525 15.21397 0.3183334 0.5168873 -0.3954757 0.8714034 1.003507 0.8492727 0.4153280 0.3800778 -0.2381677 0.05145833 0.049625 0.056875 0.007250 1.00000000 0.04262302    
ENST00000532860 ENSG00000172273 No_inf pgKDN_inf HINFP protein_coding retained_intron 16.93091 20.01525 15.21397 0.3183334 0.5168873 -0.3954757 2.4131882 3.094495 2.3202665 0.3875943 0.2725048 -0.4138637 0.14165833 0.153875 0.153950 0.000075 1.00000000 0.04262302 FALSE  
MSTRG.5643.1 ENSG00000172273 No_inf pgKDN_inf HINFP protein_coding   16.93091 20.01525 15.21397 0.3183334 0.5168873 -0.3954757 3.6477348 1.264307 3.5652606 0.5648592 1.4672788 1.4883353 0.23204167 0.062800 0.235275 0.172475 0.52567842 0.04262302 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172273 E001 0.1272623 0.0123928837 0.6507385577   11 119121575 119121579 5 + 0.000 0.088 10.458
ENSG00000172273 E002 0.1272623 0.0123928837 0.6507385577   11 119121580 119121590 11 + 0.000 0.088 12.456
ENSG00000172273 E003 0.1272623 0.0123928837 0.6507385577   11 119121591 119121591 1 + 0.000 0.088 12.456
ENSG00000172273 E004 1.1090430 0.0432886401 0.9736411649 0.99528748 11 119121592 119121608 17 + 0.316 0.327 0.072
ENSG00000172273 E005 1.2276811 0.1172497190 0.7697336001 0.91109187 11 119121609 119121609 1 + 0.368 0.327 -0.250
ENSG00000172273 E006 1.7358491 0.1222103399 0.5862328816 0.81649324 11 119121610 119121615 6 + 0.368 0.480 0.598
ENSG00000172273 E007 2.4718554 0.1965528609 0.8580767716 0.95046683 11 119121616 119121639 24 + 0.496 0.568 0.335
ENSG00000172273 E008 0.7523703 0.0153898674 0.1444977874 0.40472287 11 119121783 119122013 231 + 0.103 0.327 2.072
ENSG00000172273 E009 0.8699390 0.0127669921 0.3693915323 0.65759316 11 119123568 119123684 117 + 0.186 0.327 1.072
ENSG00000172273 E010 1.2424423 0.0814519541 0.3694670536 0.65762965 11 119123733 119123987 255 + 0.255 0.410 0.972
ENSG00000172273 E011 0.7263444 0.0142661192 0.2957552088 0.58882471 11 119123988 119124236 249 + 0.316 0.161 -1.250
ENSG00000172273 E012 8.4864690 0.0199285248 0.0008636912 0.01338573 11 119124237 119126934 2698 + 0.722 1.103 1.450
ENSG00000172273 E013 12.2894788 0.0029370748 0.0044462396 0.04564208 11 119126935 119127125 191 + 1.231 1.009 -0.800
ENSG00000172273 E014 1.2615759 0.0431131710 0.0205429009 0.12910125 11 119127126 119127458 333 + 0.103 0.480 2.920
ENSG00000172273 E015 2.1051051 0.0660275900 0.4490424177 0.72293546 11 119129860 119130724 865 + 0.415 0.540 0.624
ENSG00000172273 E016 14.8163849 0.0010582803 0.3293133072 0.62172843 11 119130725 119130954 230 + 1.231 1.167 -0.226
ENSG00000172273 E017 2.3494704 0.0061945010 0.4622646189 0.73275320 11 119130955 119131113 159 + 0.458 0.567 0.527
ENSG00000172273 E018 2.1142075 0.0080715693 0.1861577161 0.46399534 11 119131114 119131209 96 + 0.368 0.567 1.013
ENSG00000172273 E019 1.0049760 0.0712238588 0.0600245814 0.24581365 11 119131210 119131231 22 + 0.103 0.410 2.557
ENSG00000172273 E020 3.5903735 0.0041562105 0.2408324994 0.53010080 11 119131232 119131438 207 + 0.565 0.721 0.676
ENSG00000172273 E021 1.3504750 0.0103695980 0.9910097689 1.00000000 11 119131439 119131534 96 + 0.368 0.370 0.013
ENSG00000172273 E022 6.5128358 0.0310791681 0.7913145291 0.92007842 11 119131535 119131564 30 + 0.854 0.888 0.133
ENSG00000172273 E023 8.5633146 0.0116432498 0.4529501201 0.72586397 11 119131565 119131646 82 + 1.015 0.947 -0.250
ENSG00000172273 E024 0.3719033 0.1668396379 0.7464050435   11 119131647 119131829 183 + 0.103 0.161 0.750
ENSG00000172273 E025 10.1441170 0.0019681740 0.2299045961 0.51839119 11 119131830 119131982 153 + 1.096 0.999 -0.355
ENSG00000172273 E026 0.1271363 0.0123520617 0.6508200999   11 119131983 119132242 260 + 0.000 0.088 12.456
ENSG00000172273 E027 0.9982734 0.0180244372 0.2418673658 0.53153387 11 119132243 119132297 55 + 0.186 0.370 1.335
ENSG00000172273 E028 0.6356513 0.0150030183 0.0343399759 0.17694585 11 119132298 119132495 198 + 0.000 0.327 14.525
ENSG00000172273 E029 7.5669967 0.0019693110 0.2080558749 0.49179769 11 119132496 119132573 78 + 0.992 0.876 -0.437
ENSG00000172273 E030 10.2484423 0.0066177069 0.1488592280 0.41094199 11 119132661 119132781 121 + 1.114 0.989 -0.456
ENSG00000172273 E031 0.1268540 0.0126613833 0.6504433514   11 119132839 119132863 25 + 0.000 0.088 12.456
ENSG00000172273 E032 12.2924383 0.0014962942 0.9556617004 0.98928280 11 119132864 119133002 139 + 1.114 1.125 0.039
ENSG00000172273 E033 14.1285199 0.0016922885 0.8530126563 0.94815516 11 119133095 119133219 125 + 1.180 1.174 -0.024
ENSG00000172273 E034 5.0603147 0.0034669132 0.4225671748 0.70187977 11 119133220 119133898 679 + 0.722 0.820 0.394
ENSG00000172273 E035 0.9523849 0.0115257196 0.0132860184 0.09662461 11 119134022 119134083 62 + 0.458 0.088 -3.058
ENSG00000172273 E036 71.1279473 0.0002567779 0.9241060299 0.97695120 11 119134084 119136059 1976 + 1.853 1.857 0.015

Help

Please Click HERE to learn more details about the results from DEXseq.