ENSG00000172375

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000336702 ENSG00000172375 No_inf pgKDN_inf C2CD2L protein_coding protein_coding 23.87715 21.84725 23.89097 0.7574451 1.288646 0.1289571 5.138723 5.336179 3.3699153 1.5325271 0.9899454 -0.6615209 0.21339167 0.245700 0.136325 -0.109375 0.72533923 0.02622951 FALSE TRUE
ENST00000525598 ENSG00000172375 No_inf pgKDN_inf C2CD2L protein_coding retained_intron 23.87715 21.84725 23.89097 0.7574451 1.288646 0.1289571 1.927696 3.628384 0.8215988 0.1721050 0.2235202 -2.1293384 0.08438333 0.166300 0.034950 -0.131350 0.02622951 0.02622951 TRUE TRUE
ENST00000529874 ENSG00000172375 No_inf pgKDN_inf C2CD2L protein_coding retained_intron 23.87715 21.84725 23.89097 0.7574451 1.288646 0.1289571 2.937682 2.369314 1.4490695 0.9559295 1.4490695 -0.7054972 0.11568333 0.105850 0.052450 -0.053400 0.47536323 0.02622951 FALSE TRUE
ENST00000648610 ENSG00000172375 No_inf pgKDN_inf C2CD2L protein_coding protein_coding 23.87715 21.84725 23.89097 0.7574451 1.288646 0.1289571 13.123787 9.253330 18.1338706 1.7348917 1.1650554 0.9698795 0.55355000 0.423475 0.771350 0.347875 0.05422691 0.02622951 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172375 E001 0.0000000       11 119102198 119102375 178 +      
ENSG00000172375 E002 0.2541163 0.0160327440 2.760749e-01   11 119106715 119106741 27 + 0.000 0.167 11.219
ENSG00000172375 E003 0.2541163 0.0160327440 2.760749e-01   11 119106742 119106749 8 + 0.000 0.167 13.146
ENSG00000172375 E004 0.2541163 0.0160327440 2.760749e-01   11 119106750 119106774 25 + 0.000 0.167 13.146
ENSG00000172375 E005 0.1272623 0.0123851535 5.902194e-01   11 119106775 119106878 104 + 0.000 0.092 12.200
ENSG00000172375 E006 0.0000000       11 119106879 119106941 63 +      
ENSG00000172375 E007 0.1272623 0.0123851535 5.902194e-01   11 119106942 119107070 129 + 0.000 0.092 12.200
ENSG00000172375 E008 0.1272623 0.0123851535 5.902194e-01   11 119107071 119107126 56 + 0.000 0.092 12.200
ENSG00000172375 E009 0.1272623 0.0123851535 5.902194e-01   11 119107127 119107343 217 + 0.000 0.092 12.200
ENSG00000172375 E010 0.0000000       11 119107344 119107374 31 +      
ENSG00000172375 E011 0.0000000       11 119107375 119107382 8 +      
ENSG00000172375 E012 0.0000000       11 119107383 119107512 130 +      
ENSG00000172375 E013 0.0000000       11 119107513 119108095 583 +      
ENSG00000172375 E014 0.4999558 0.0152546132 3.665412e-01 6.552537e-01 11 119110103 119110103 1 + 0.099 0.232 1.465
ENSG00000172375 E015 13.4221219 0.0010410547 1.499248e-01 4.124271e-01 11 119110104 119110199 96 + 1.212 1.105 -0.383
ENSG00000172375 E016 12.3804535 0.0011116732 8.637873e-01 9.528784e-01 11 119110561 119110586 26 + 1.130 1.121 -0.034
ENSG00000172375 E017 18.2057708 0.0244203856 2.982049e-01 5.912139e-01 11 119110587 119110680 94 + 1.325 1.241 -0.294
ENSG00000172375 E018 1.2522615 0.0100074688 7.156477e-02 2.710928e-01 11 119110681 119110846 166 + 0.179 0.459 1.880
ENSG00000172375 E019 23.8757433 0.0008038074 3.844492e-01 6.705978e-01 11 119110847 119110957 111 + 1.419 1.372 -0.165
ENSG00000172375 E020 11.9765021 0.0012113007 2.868611e-01 5.802590e-01 11 119111052 119111056 5 + 1.154 1.072 -0.297
ENSG00000172375 E021 26.6500009 0.0005792446 1.300792e-01 3.826375e-01 11 119111057 119111168 112 + 1.482 1.401 -0.279
ENSG00000172375 E022 24.8093459 0.0005693664 1.118750e-01 3.513014e-01 11 119111263 119111374 112 + 1.456 1.367 -0.305
ENSG00000172375 E023 14.0094525 0.0017432967 3.903491e-02 1.912923e-01 11 119111521 119111560 40 + 1.251 1.097 -0.550
ENSG00000172375 E024 20.1592735 0.0120845109 2.067028e-01 4.903374e-01 11 119111561 119111629 69 + 1.370 1.281 -0.313
ENSG00000172375 E025 7.9860326 0.0183791162 9.332999e-04 1.423545e-02 11 119111630 119112327 698 + 0.706 1.089 1.465
ENSG00000172375 E026 20.8877688 0.0008637628 1.459399e-01 4.068394e-01 11 119112328 119112392 65 + 1.384 1.296 -0.306
ENSG00000172375 E027 0.2438580 0.0163574635 9.418748e-01   11 119112393 119112481 89 + 0.099 0.092 -0.120
ENSG00000172375 E028 30.2985271 0.0005411208 5.782751e-02 2.406536e-01 11 119112482 119112609 128 + 1.543 1.447 -0.330
ENSG00000172375 E029 37.7176555 0.0003910730 1.654072e-02 1.119849e-01 11 119112700 119112874 175 + 1.642 1.533 -0.373
ENSG00000172375 E030 6.1352501 0.0281938374 1.766999e-04 3.781798e-03 11 119112875 119113610 736 + 0.518 1.017 2.032
ENSG00000172375 E031 14.4744311 0.0028382725 8.254158e-01 9.367866e-01 11 119113611 119113636 26 + 1.177 1.198 0.076
ENSG00000172375 E032 25.8208574 0.0006044954 2.611858e-01 5.538911e-01 11 119113637 119113712 76 + 1.389 1.458 0.239
ENSG00000172375 E033 4.2619667 0.0033056120 2.804517e-04 5.496322e-03 11 119113713 119113851 139 + 0.403 0.879 2.102
ENSG00000172375 E034 4.7269570 0.0613344231 6.812583e-02 2.633339e-01 11 119113852 119113854 3 + 0.580 0.866 1.176
ENSG00000172375 E035 41.5762979 0.0006618672 9.614505e-01 9.915837e-01 11 119113855 119113988 134 + 1.627 1.629 0.008
ENSG00000172375 E036 0.6256726 0.0148717626 2.072645e-01 4.909516e-01 11 119113989 119114079 91 + 0.099 0.288 1.880
ENSG00000172375 E037 76.2744974 0.0002132056 1.512926e-01 4.146459e-01 11 119114080 119114365 286 + 1.909 1.867 -0.143
ENSG00000172375 E038 26.1288190 0.0005537748 9.598315e-24 3.594969e-21 11 119114366 119116024 1659 + 0.950 1.629 2.393
ENSG00000172375 E039 1.2599737 0.0137257346 1.137018e-02 8.755558e-02 11 119116025 119116044 20 + 0.099 0.493 3.050
ENSG00000172375 E040 212.9021645 0.0001067091 8.318783e-01 9.392783e-01 11 119116045 119118544 2500 + 2.328 2.329 0.003

Help

Please Click HERE to learn more details about the results from DEXseq.