ENSG00000172432

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000307114 ENSG00000172432 No_inf pgKDN_inf GTPBP2 protein_coding protein_coding 57.13641 68.13942 46.29958 2.370435 1.144953 -0.5573907 2.464253 0.000000 3.285440 0.000000 3.2854397 8.3643272 0.04863333 0.000000 0.075300 0.075300 0.83007012 0.02743032 FALSE TRUE
ENST00000307126 ENSG00000172432 No_inf pgKDN_inf GTPBP2 protein_coding protein_coding 57.13641 68.13942 46.29958 2.370435 1.144953 -0.5573907 13.988101 9.675219 14.852988 1.952410 1.5403713 0.6178676 0.25690000 0.145325 0.319225 0.173900 0.08560089 0.02743032 FALSE TRUE
ENST00000419497 ENSG00000172432 No_inf pgKDN_inf GTPBP2 protein_coding protein_coding 57.13641 68.13942 46.29958 2.370435 1.144953 -0.5573907 8.079939 9.550343 7.642776 1.341832 2.6878389 -0.3210791 0.14054167 0.138650 0.161375 0.022725 0.99949038 0.02743032 FALSE FALSE
ENST00000459959 ENSG00000172432 No_inf pgKDN_inf GTPBP2 protein_coding protein_coding_CDS_not_defined 57.13641 68.13942 46.29958 2.370435 1.144953 -0.5573907 9.590962 15.523494 5.459401 1.276834 0.3885056 -1.5059277 0.16058333 0.227350 0.118750 -0.108600 0.11947201 0.02743032   FALSE
ENST00000476510 ENSG00000172432 No_inf pgKDN_inf GTPBP2 protein_coding protein_coding_CDS_not_defined 57.13641 68.13942 46.29958 2.370435 1.144953 -0.5573907 6.784840 12.947331 1.717130 2.488907 1.7171301 -2.9073199 0.10892500 0.186975 0.037900 -0.149075 0.02743032 0.02743032 FALSE TRUE
MSTRG.24743.7 ENSG00000172432 No_inf pgKDN_inf GTPBP2 protein_coding   57.13641 68.13942 46.29958 2.370435 1.144953 -0.5573907 10.958364 12.274212 10.451852 1.248198 1.1138185 -0.2316671 0.19515833 0.180275 0.225150 0.044875 0.81257222 0.02743032 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172432 E001 0.0000000       6 43605316 43605382 67 -      
ENSG00000172432 E002 0.0000000       6 43620119 43620333 215 -      
ENSG00000172432 E003 0.0000000       6 43620482 43620489 8 -      
ENSG00000172432 E004 0.0000000       6 43620490 43620493 4 -      
ENSG00000172432 E005 0.0000000       6 43620494 43620510 17 -      
ENSG00000172432 E006 0.4897859 4.829794e-01 7.863975e-01   6 43620511 43620533 23 - 0.200 0.149 -0.518
ENSG00000172432 E007 235.6979474 9.485257e-05 9.488835e-01 0.9867620019 6 43620534 43621516 983 - 2.363 2.365 0.008
ENSG00000172432 E008 60.7982345 2.698217e-04 7.686262e-02 0.2834923294 6 43621517 43621721 205 - 1.737 1.807 0.236
ENSG00000172432 E009 26.4253239 5.437133e-04 5.046264e-01 0.7636938869 6 43621722 43621760 39 - 1.404 1.444 0.139
ENSG00000172432 E010 28.1572359 5.407365e-04 4.549043e-01 0.7276598156 6 43621761 43621790 30 - 1.428 1.472 0.150
ENSG00000172432 E011 2.3571518 5.784706e-03 4.009108e-01 0.6841334334 6 43621791 43622002 212 - 0.441 0.563 0.596
ENSG00000172432 E012 57.0246962 2.109376e-03 5.876357e-01 0.8170126028 6 43622003 43622167 165 - 1.767 1.745 -0.074
ENSG00000172432 E013 48.6450717 3.339721e-04 6.946003e-02 0.2663720844 6 43622633 43622804 172 - 1.730 1.655 -0.257
ENSG00000172432 E014 32.0583852 7.350388e-03 3.210453e-06 0.0001277879 6 43622951 43623612 662 - 1.296 1.607 1.073
ENSG00000172432 E015 22.6391257 1.722588e-03 5.094558e-01 0.7673333590 6 43623737 43623795 59 - 1.388 1.348 -0.141
ENSG00000172432 E016 38.4364854 1.211391e-03 6.525696e-01 0.8536667997 6 43623933 43624068 136 - 1.599 1.577 -0.072
ENSG00000172432 E017 0.1271363 1.234618e-02 7.767882e-01   6 43624472 43624509 38 - 0.000 0.081 9.808
ENSG00000172432 E018 23.2213866 6.547420e-04 1.633340e-01 0.4321016990 6 43624510 43624560 51 - 1.423 1.339 -0.290
ENSG00000172432 E019 25.4635937 5.488014e-04 3.887180e-01 0.6745532823 6 43624561 43624613 53 - 1.442 1.393 -0.170
ENSG00000172432 E020 27.3153500 5.122011e-04 4.163219e-01 0.6961810574 6 43624614 43624662 49 - 1.469 1.424 -0.154
ENSG00000172432 E021 27.6247177 2.947593e-03 8.112134e-01 0.9305245249 6 43624663 43624729 67 - 1.437 1.453 0.054
ENSG00000172432 E022 6.9516169 2.457014e-03 1.030509e-01 0.3355332475 6 43624730 43624887 158 - 0.777 0.953 0.678
ENSG00000172432 E023 42.3199158 3.454044e-04 6.825781e-01 0.8685848222 6 43624888 43625062 175 - 1.614 1.635 0.069
ENSG00000172432 E024 26.9882465 2.799706e-03 9.750576e-01 0.9954336259 6 43625063 43625362 300 - 1.437 1.437 -0.001
ENSG00000172432 E025 37.5931156 6.668141e-04 9.366569e-02 0.3182414720 6 43625363 43625560 198 - 1.624 1.543 -0.274
ENSG00000172432 E026 25.8316110 1.369592e-03 2.848292e-01 0.5785929668 6 43625756 43625864 109 - 1.378 1.444 0.228
ENSG00000172432 E027 25.5737965 5.505872e-04 3.463077e-01 0.6371183166 6 43626226 43626386 161 - 1.447 1.393 -0.185
ENSG00000172432 E028 7.1980164 6.072358e-03 4.851530e-02 0.2168772607 6 43626387 43626410 24 - 1.016 0.814 -0.765
ENSG00000172432 E029 6.8451525 6.853666e-02 1.946306e-01 0.4746107659 6 43626922 43626948 27 - 0.978 0.814 -0.623
ENSG00000172432 E030 1.0052583 1.159602e-02 8.089619e-02 0.2922828748 6 43626949 43627017 69 - 0.112 0.386 2.288
ENSG00000172432 E031 0.5072867 3.831842e-02 1.039119e-01 0.3368669937 6 43627279 43627353 75 - 0.000 0.260 11.550
ENSG00000172432 E032 0.1268540 1.235078e-02 7.767666e-01   6 43628789 43628976 188 - 0.000 0.081 9.808
ENSG00000172432 E033 11.0212048 2.210185e-02 1.441875e-01 0.4043511988 6 43628977 43629264 288 - 1.152 1.009 -0.520

Help

Please Click HERE to learn more details about the results from DEXseq.