ENSG00000172531

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000376745 ENSG00000172531 No_inf pgKDN_inf PPP1CA protein_coding protein_coding 145.8027 156.2298 148.6145 2.767188 1.656468 -0.07209025 130.8538 133.4931 138.4329 3.673497 1.283974 0.05241772 0.898925 0.854225 0.9317 0.077475 0.003665337 0.003665337 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172531 E001 0.0000000       11 67398181 67398182 2 -      
ENSG00000172531 E002 0.0000000       11 67398183 67398196 14 -      
ENSG00000172531 E003 0.0000000       11 67398197 67398200 4 -      
ENSG00000172531 E004 0.0000000       11 67398201 67398201 1 -      
ENSG00000172531 E005 0.0000000       11 67398202 67398208 7 -      
ENSG00000172531 E006 25.9589149 0.0005375405 0.7344643238 0.894619969 11 67398209 67398430 222 - 1.413 1.438 0.084
ENSG00000172531 E007 217.7744805 0.0004020246 0.3758774115 0.663129219 11 67398431 67398645 215 - 2.324 2.346 0.076
ENSG00000172531 E008 169.0042474 0.0014028211 0.8099321329 0.929858224 11 67398722 67398856 135 - 2.221 2.232 0.037
ENSG00000172531 E009 1.8866839 0.0246382935 0.0107814631 0.084408104 11 67398857 67398939 83 - 0.186 0.592 2.441
ENSG00000172531 E010 200.1885010 0.0024357359 0.1438337742 0.403806714 11 67398940 67399163 224 - 2.275 2.319 0.147
ENSG00000172531 E011 5.5928747 0.0036507895 0.0270104934 0.152702720 11 67399164 67399560 397 - 0.651 0.912 1.040
ENSG00000172531 E012 136.5911977 0.0014348391 0.9685327606 0.993641226 11 67399561 67399665 105 - 2.132 2.137 0.019
ENSG00000172531 E013 4.7706710 0.0034254757 0.0001373125 0.003080622 11 67399666 67400688 1023 - 0.416 0.912 2.155
ENSG00000172531 E014 66.4244461 0.0037698708 0.7535649402 0.903072358 11 67400689 67400715 27 - 1.815 1.833 0.062
ENSG00000172531 E015 138.8135314 0.0001356837 0.5457163700 0.791583742 11 67400716 67400854 139 - 2.148 2.137 -0.035
ENSG00000172531 E016 53.1478732 0.0002611690 0.4319385200 0.709492071 11 67400855 67400858 4 - 1.745 1.718 -0.093
ENSG00000172531 E017 93.2400345 0.0001744316 0.0185682275 0.120759530 11 67400859 67400919 61 - 2.007 1.940 -0.226
ENSG00000172531 E018 1.5820252 0.0202554284 0.2544165636 0.546096766 11 67400920 67401067 148 - 0.497 0.326 -0.938
ENSG00000172531 E019 120.5442333 0.0001703300 0.0059228799 0.055983983 11 67401068 67401199 132 - 2.119 2.050 -0.231
ENSG00000172531 E020 4.7013688 0.0031349284 0.2997244785 0.592608225 11 67401200 67401232 33 - 0.677 0.804 0.518
ENSG00000172531 E021 6.6539777 0.0083206081 0.7051327584 0.880156635 11 67401233 67401384 152 - 0.855 0.899 0.171
ENSG00000172531 E022 7.7416918 0.0825009589 0.0168428617 0.113183202 11 67401385 67401727 343 - 0.677 1.069 1.516
ENSG00000172531 E023 74.4152729 0.0002435687 0.0782019784 0.286201093 11 67401728 67401871 144 - 1.905 1.849 -0.189
ENSG00000172531 E024 0.6357773 0.0281366815 0.0358876656 0.181709102 11 67404871 67404921 51 - 0.000 0.326 11.229
ENSG00000172531 E025 0.0000000       11 67407079 67407264 186 -      
ENSG00000172531 E026 0.8892332 0.0337234790 0.0100667508 0.080674612 11 67419408 67419443 36 - 0.000 0.409 11.715
ENSG00000172531 E027 0.0000000       11 67419444 67419597 154 -      
ENSG00000172531 E028 0.0000000       11 67420979 67421183 205 -      

Help

Please Click HERE to learn more details about the results from DEXseq.