ENSG00000172590

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000355151 ENSG00000172590 No_inf pgKDN_inf MRPL52 protein_coding protein_coding 55.20219 31.72148 65.85821 1.254051 3.325473 1.053667 15.582497 7.494044 22.822544 0.8485423 1.4326331 1.6053514 0.27632500 0.236850 0.351625 0.114775 0.45243234 0.04041804 FALSE  
ENST00000397496 ENSG00000172590 No_inf pgKDN_inf MRPL52 protein_coding protein_coding 55.20219 31.72148 65.85821 1.254051 3.325473 1.053667 4.633200 5.809899 2.974972 0.6332094 2.5457137 -0.9632768 0.10151667 0.183975 0.045700 -0.138275 0.09955995 0.04041804 FALSE  
ENST00000461594 ENSG00000172590 No_inf pgKDN_inf MRPL52 protein_coding protein_coding_CDS_not_defined 55.20219 31.72148 65.85821 1.254051 3.325473 1.053667 3.490378 0.000000 5.449857 0.0000000 2.0842834 9.0927194 0.04679167 0.000000 0.078575 0.078575 0.04461358 0.04041804    
ENST00000553965 ENSG00000172590 No_inf pgKDN_inf MRPL52 protein_coding retained_intron 55.20219 31.72148 65.85821 1.254051 3.325473 1.053667 2.637051 3.073416 2.220776 0.6015154 0.4718764 -0.4669839 0.05604167 0.095650 0.034275 -0.061375 0.26348424 0.04041804    
ENST00000555345 ENSG00000172590 No_inf pgKDN_inf MRPL52 protein_coding protein_coding 55.20219 31.72148 65.85821 1.254051 3.325473 1.053667 20.431817 9.979435 24.178147 1.1560811 3.8901459 1.2758253 0.36234167 0.313425 0.363725 0.050300 0.84643505 0.04041804    
ENST00000557543 ENSG00000172590 No_inf pgKDN_inf MRPL52 protein_coding retained_intron 55.20219 31.72148 65.85821 1.254051 3.325473 1.053667 3.570139 4.045041 2.769230 0.1509732 0.2001357 -0.5450311 0.07621667 0.128175 0.042075 -0.086100 0.04041804 0.04041804    
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172590 E001 0.117004 0.0117271250 1.000000e+00   14 22829879 22829882 4 + 0.074 0.000 -8.866
ENSG00000172590 E002 0.117004 0.0117271250 1.000000e+00   14 22829883 22829886 4 + 0.074 0.000 -11.211
ENSG00000172590 E003 3.130976 0.0044781390 2.807362e-01 5.739317e-01 14 22829887 22829894 8 + 0.659 0.511 -0.666
ENSG00000172590 E004 7.644336 0.0018368045 8.584426e-01 9.506568e-01 14 22829895 22829902 8 + 0.919 0.939 0.074
ENSG00000172590 E005 9.566106 0.0015539373 7.749918e-01 9.135413e-01 14 22829903 22829905 3 + 1.023 0.998 -0.090
ENSG00000172590 E006 12.349291 0.0011738873 7.204021e-01 8.874416e-01 14 22829906 22829909 4 + 1.125 1.098 -0.100
ENSG00000172590 E007 14.269394 0.0011078526 4.831280e-01 7.478771e-01 14 22829910 22829912 3 + 1.193 1.140 -0.189
ENSG00000172590 E008 14.760917 0.0010438872 5.542920e-01 7.971032e-01 14 22829913 22829913 1 + 1.203 1.160 -0.155
ENSG00000172590 E009 17.200351 0.0008200892 7.889339e-01 9.189725e-01 14 22829914 22829915 2 + 1.256 1.239 -0.061
ENSG00000172590 E010 19.990480 0.0006826375 7.391171e-01 8.965924e-01 14 22829916 22829920 5 + 1.319 1.299 -0.071
ENSG00000172590 E011 20.842259 0.0006872805 7.938533e-01 9.213804e-01 14 22829921 22829928 8 + 1.334 1.319 -0.052
ENSG00000172590 E012 25.581292 0.0005404838 8.775781e-01 9.584351e-01 14 22829929 22829940 12 + 1.416 1.409 -0.025
ENSG00000172590 E013 7.643651 0.0018528669 9.367435e-01 9.819565e-01 14 22829941 22829948 8 + 0.929 0.922 -0.024
ENSG00000172590 E014 11.569025 0.0099002237 9.561205e-02 3.219341e-01 14 22829949 22830048 100 + 1.143 0.984 -0.579
ENSG00000172590 E015 5.046480 0.0266903624 9.899781e-02 3.284590e-01 14 22830049 22830049 1 + 0.844 0.623 -0.903
ENSG00000172590 E016 23.027167 0.0005886834 1.578103e-02 1.087711e-01 14 22830050 22830052 3 + 1.422 1.270 -0.531
ENSG00000172590 E017 52.419089 0.0002972914 2.048579e-01 4.880340e-01 14 22830053 22830110 58 + 1.735 1.685 -0.171
ENSG00000172590 E018 60.092670 0.0011573286 5.035287e-02 2.217286e-01 14 22830187 22830254 68 + 1.803 1.726 -0.260
ENSG00000172590 E019 9.538402 0.0015091737 2.341169e-07 1.248948e-05 14 22830255 22830963 709 + 0.768 1.239 1.747
ENSG00000172590 E020 4.092307 0.0909369382 7.492215e-03 6.612423e-02 14 22830964 22831037 74 + 0.486 0.905 1.774
ENSG00000172590 E021 20.796759 0.0007407841 5.806197e-13 7.848407e-11 14 22831038 22832078 1041 + 1.087 1.551 1.623
ENSG00000172590 E022 7.397731 0.0019282028 3.416454e-04 6.467639e-03 14 22833267 22833417 151 + 0.740 1.098 1.360
ENSG00000172590 E023 65.988621 0.0002724931 2.371632e-01 5.261381e-01 14 22833418 22833482 65 + 1.830 1.789 -0.139
ENSG00000172590 E024 2.540580 0.0055594713 7.291172e-01 8.920027e-01 14 22833483 22833489 7 + 0.559 0.511 -0.225
ENSG00000172590 E025 113.458433 0.0017058283 8.138723e-01 9.319417e-01 14 22834172 22835037 866 + 2.044 2.052 0.027

Help

Please Click HERE to learn more details about the results from DEXseq.