ENSG00000172869

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000311085 ENSG00000172869 No_inf pgKDN_inf DMXL1 protein_coding protein_coding 6.388085 5.147271 6.839773 0.4405385 0.7631822 0.4094484 0.6150699 0.2946293 0.7500974 0.2946293 0.5057662 1.3191295 0.13005833 0.072675 0.144600 0.071925 0.84712738 0.01509679 FALSE TRUE
ENST00000502516 ENSG00000172869 No_inf pgKDN_inf DMXL1 protein_coding protein_coding_CDS_not_defined 6.388085 5.147271 6.839773 0.4405385 0.7631822 0.4094484 1.0422323 0.0000000 0.0000000 0.0000000 0.0000000 0.0000000 0.09500000 0.000000 0.000000 0.000000   0.01509679 FALSE FALSE
ENST00000505312 ENSG00000172869 No_inf pgKDN_inf DMXL1 protein_coding protein_coding_CDS_not_defined 6.388085 5.147271 6.839773 0.4405385 0.7631822 0.4094484 2.3302881 2.0665855 3.0201468 0.6936615 0.2840439 0.5451744 0.38312500 0.379450 0.447550 0.068100 0.87547845 0.01509679 TRUE TRUE
ENST00000507552 ENSG00000172869 No_inf pgKDN_inf DMXL1 protein_coding protein_coding_CDS_not_defined 6.388085 5.147271 6.839773 0.4405385 0.7631822 0.4094484 0.1684940 0.0000000 0.5054819 0.0000000 0.5054819 5.6878499 0.02365833 0.000000 0.070975 0.070975 0.85780767 0.01509679 FALSE FALSE
ENST00000510924 ENSG00000172869 No_inf pgKDN_inf DMXL1 protein_coding protein_coding_CDS_not_defined 6.388085 5.147271 6.839773 0.4405385 0.7631822 0.4094484 0.2006291 0.0000000 0.6018874 0.0000000 0.6018874 5.9351944 0.02748333 0.000000 0.082450 0.082450 0.85750911 0.01509679   FALSE
ENST00000514595 ENSG00000172869 No_inf pgKDN_inf DMXL1 protein_coding retained_intron 6.388085 5.147271 6.839773 0.4405385 0.7631822 0.4094484 0.4296479 1.2889438 0.0000000 0.5100838 0.0000000 -7.0211952 0.09319167 0.279575 0.000000 -0.279575 0.01509679 0.01509679 FALSE TRUE
MSTRG.23388.4 ENSG00000172869 No_inf pgKDN_inf DMXL1 protein_coding   6.388085 5.147271 6.839773 0.4405385 0.7631822 0.4094484 0.9172151 1.0834314 0.8618633 0.3747243 0.5123518 -0.3266889 0.15655833 0.196500 0.112400 -0.084100 0.82258322 0.01509679 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172869 E001 0.0000000       5 119037772 119037888 117 +      
ENSG00000172869 E002 0.0000000       5 119044870 119044978 109 +      
ENSG00000172869 E003 0.1272623 0.0124801179 0.5408378989   5 119071087 119071204 118 + 0.000 0.095 10.382
ENSG00000172869 E004 0.1272623 0.0124801179 0.5408378989   5 119071205 119071212 8 + 0.000 0.095 12.873
ENSG00000172869 E005 0.4900381 0.0162758437 0.9958271001   5 119071213 119071257 45 + 0.174 0.172 -0.013
ENSG00000172869 E006 0.6079886 0.0148877203 0.6506961298 0.852929691 5 119071258 119071489 232 + 0.240 0.172 -0.598
ENSG00000172869 E007 0.4814816 0.0154769913 0.3156912770   5 119071490 119071528 39 + 0.240 0.095 -1.598
ENSG00000172869 E008 0.2447669 0.0163623267 0.9962459037   5 119071529 119071554 26 + 0.095 0.095 -0.013
ENSG00000172869 E009 0.5902332 0.0354920599 0.0215462138 0.132975569 5 119071555 119071656 102 + 0.348 0.000 -15.565
ENSG00000172869 E010 0.1176306 0.0118058799 0.5355111589   5 119081574 119081697 124 + 0.095 0.000 -13.654
ENSG00000172869 E011 1.5508652 0.0090187053 0.0092065635 0.076145805 5 119097979 119098104 126 + 0.569 0.172 -2.472
ENSG00000172869 E012 0.1268540 0.0122871301 0.5411668778   5 119100601 119100671 71 + 0.000 0.095 12.873
ENSG00000172869 E013 0.9722448 0.0142246922 0.4765044665 0.743004767 5 119101935 119102006 72 + 0.348 0.238 -0.750
ENSG00000172869 E014 0.0000000       5 119102007 119102210 204 +      
ENSG00000172869 E015 0.0000000       5 119104128 119104280 153 +      
ENSG00000172869 E016 0.7540070 0.0139151998 0.0948035480 0.320302175 5 119105180 119105222 43 + 0.095 0.346 2.309
ENSG00000172869 E017 0.7446577 0.0136831120 0.4193927918 0.698996626 5 119105223 119105258 36 + 0.174 0.296 0.987
ENSG00000172869 E018 0.0000000       5 119105259 119105259 1 +      
ENSG00000172869 E019 1.7313532 0.0075637453 0.2918760470 0.585227805 5 119110151 119110283 133 + 0.348 0.504 0.835
ENSG00000172869 E020 0.4987910 0.5115671323 0.5736213747   5 119114475 119114541 67 + 0.095 0.238 1.575
ENSG00000172869 E021 2.5744742 0.0087553174 0.8399751003 0.942588222 5 119116158 119116336 179 + 0.539 0.566 0.125
ENSG00000172869 E022 2.3314390 0.0059737786 0.8342765202 0.940355913 5 119118815 119119004 190 + 0.507 0.536 0.139
ENSG00000172869 E023 2.0681679 0.0069888206 0.4614683505 0.732185759 5 119120971 119121139 169 + 0.539 0.432 -0.527
ENSG00000172869 E024 0.0000000       5 119129209 119129210 2 +      
ENSG00000172869 E025 1.5853343 0.0090297517 0.7736264135 0.912934688 5 119129211 119129423 213 + 0.435 0.391 -0.235
ENSG00000172869 E026 2.3273504 0.0064634024 0.8324891398 0.939590958 5 119133132 119133385 254 + 0.507 0.536 0.139
ENSG00000172869 E027 0.0000000       5 119133386 119133485 100 +      
ENSG00000172869 E028 1.3421368 0.0672021318 0.7523979463 0.902459274 5 119133494 119133726 233 + 0.394 0.346 -0.276
ENSG00000172869 E029 3.0444339 0.0050065047 0.5407221638 0.788634168 5 119133727 119134178 452 + 0.648 0.566 -0.361
ENSG00000172869 E030 0.1271363 0.0123591329 0.5410394604   5 119134226 119134267 42 + 0.000 0.095 12.873
ENSG00000172869 E031 1.1045122 0.0120893147 0.7500579940 0.901457506 5 119134268 119134389 122 + 0.297 0.346 0.309
ENSG00000172869 E032 0.7237664 0.0822273145 0.4432695413 0.718259342 5 119143841 119143930 90 + 0.297 0.172 -1.012
ENSG00000172869 E033 0.9532402 0.0123610645 0.0255776866 0.147588205 5 119144536 119144638 103 + 0.435 0.095 -2.820
ENSG00000172869 E034 0.7267188 0.0142774667 0.4081711503 0.690559584 5 119146837 119146956 120 + 0.297 0.172 -1.013
ENSG00000172869 E035 1.3330729 0.0102442011 0.3600346229 0.649587106 5 119147249 119147470 222 + 0.435 0.296 -0.820
ENSG00000172869 E036 0.0000000       5 119147471 119147582 112 +      
ENSG00000172869 E037 11.4490875 0.0013416123 0.1327043395 0.386733444 5 119148739 119150421 1683 + 1.155 1.031 -0.446
ENSG00000172869 E038 1.4424907 0.0091111951 0.0771022010 0.284054993 5 119151929 119152036 108 + 0.507 0.238 -1.598
ENSG00000172869 E039 2.0821990 0.0081351497 0.8181265515 0.933799704 5 119164507 119164676 170 + 0.472 0.504 0.157
ENSG00000172869 E040 1.9582699 0.0077395391 0.9900104934 1.000000000 5 119165183 119165280 98 + 0.472 0.470 -0.013
ENSG00000172869 E041 1.7853724 0.0230625171 0.0036641679 0.039972337 5 119166616 119166781 166 + 0.623 0.172 -2.713
ENSG00000172869 E042 0.4702767 0.0157626492 0.0445404856   5 119167603 119167628 26 + 0.297 0.000 -15.339
ENSG00000172869 E043 1.3320044 0.0420602819 0.3728918628 0.660597901 5 119167629 119167864 236 + 0.435 0.296 -0.820
ENSG00000172869 E044 4.6312829 0.0032287010 0.5026104650 0.762268512 5 119170190 119170715 526 + 0.790 0.711 -0.317
ENSG00000172869 E045 4.6629813 0.0101582377 0.7648255678 0.908508575 5 119170716 119171280 565 + 0.734 0.769 0.139
ENSG00000172869 E046 2.9254011 0.1460180339 0.6608502553 0.858471387 5 119171778 119171969 192 + 0.648 0.536 -0.499
ENSG00000172869 E047 1.1250940 0.0128481154 0.0926070166 0.316100406 5 119175261 119175337 77 + 0.174 0.432 1.795
ENSG00000172869 E048 2.0837471 0.0069254293 0.8209553209 0.935014504 5 119177357 119177484 128 + 0.472 0.504 0.157
ENSG00000172869 E049 5.7535765 0.0048299912 0.9030052527 0.968864658 5 119177996 119178244 249 + 0.823 0.836 0.049
ENSG00000172869 E050 4.8121766 0.0032093458 0.1557730744 0.421844999 5 119189708 119189886 179 + 0.671 0.836 0.665
ENSG00000172869 E051 4.1809595 0.0038837620 0.5104005839 0.768005241 5 119193828 119193970 143 + 0.671 0.751 0.328
ENSG00000172869 E052 3.9202070 0.0047745314 0.9838380305 0.998690715 5 119196371 119196456 86 + 0.693 0.690 -0.013
ENSG00000172869 E053 1.5869714 0.0088747119 0.7747753327 0.913493219 5 119197755 119197757 3 + 0.435 0.391 -0.235
ENSG00000172869 E054 1.5966953 0.0081511229 0.7940076774 0.921442660 5 119197758 119197818 61 + 0.394 0.432 0.210
ENSG00000172869 E055 2.6129351 0.0069605292 0.0503070015 0.221653281 5 119197819 119197956 138 + 0.394 0.668 1.309
ENSG00000172869 E056 4.4193289 0.0304115973 0.7670775815 0.909764976 5 119203319 119203436 118 + 0.714 0.751 0.148
ENSG00000172869 E057 0.0000000       5 119206497 119206833 337 +      
ENSG00000172869 E058 0.2454921 0.0163109037 0.9959885127   5 119206834 119206896 63 + 0.095 0.095 -0.013
ENSG00000172869 E059 4.1664114 0.0327994963 0.9957959847 1.000000000 5 119216901 119216987 87 + 0.714 0.711 -0.013
ENSG00000172869 E060 3.3966674 0.0639300650 0.1861227822 0.463995337 5 119220472 119220593 122 + 0.735 0.536 -0.861
ENSG00000172869 E061 2.9133401 0.0052252167 0.2134980295 0.498736492 5 119220940 119221081 142 + 0.671 0.504 -0.750
ENSG00000172869 E062 2.0926507 0.0070292251 0.4791566676 0.745029426 5 119224709 119224769 61 + 0.435 0.536 0.502
ENSG00000172869 E063 5.1538860 0.0030720436 0.7772258170 0.914453758 5 119233340 119233467 128 + 0.772 0.804 0.125
ENSG00000172869 E064 1.2689449 0.0130137506 0.0005202813 0.009008299 5 119236314 119237321 1008 + 0.000 0.536 15.654
ENSG00000172869 E065 4.4150854 0.0039578019 0.7524172629 0.902459274 5 119237322 119237414 93 + 0.714 0.751 0.148
ENSG00000172869 E066 3.6708033 0.0436146053 0.9902881865 1.000000000 5 119238989 119239080 92 + 0.671 0.668 -0.013
ENSG00000172869 E067 1.7402572 0.0176875278 0.1148375941 0.357188627 5 119240419 119240471 53 + 0.297 0.536 1.309
ENSG00000172869 E068 6.7233008 0.0022086787 0.6645384978 0.860591389 5 119244359 119244576 218 + 0.910 0.865 -0.170
ENSG00000172869 E069 70.3332250 0.0003453978 0.1150005991 0.357413032 5 119246995 119249291 2297 + 1.829 1.874 0.154

Help

Please Click HERE to learn more details about the results from DEXseq.