ENSG00000172890

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000319023 ENSG00000172890 No_inf pgKDN_inf NADSYN1 protein_coding protein_coding 45.42551 71.56721 24.68916 16.30331 0.3784415 -1.535038 5.2495546 0.000000 8.626913 0.0000000 1.2363770 9.75437200 0.19680833 0.000000 0.351975 0.351975 1.147618e-16 1.147618e-16 FALSE TRUE
ENST00000530055 ENSG00000172890 No_inf pgKDN_inf NADSYN1 protein_coding protein_coding 45.42551 71.56721 24.68916 16.30331 0.3784415 -1.535038 6.0601974 9.841048 3.093663 0.6471244 1.8126964 -1.66630543 0.14473333 0.170050 0.125950 -0.044100 7.513099e-01 1.147618e-16 FALSE TRUE
MSTRG.5102.19 ENSG00000172890 No_inf pgKDN_inf NADSYN1 protein_coding   45.42551 71.56721 24.68916 16.30331 0.3784415 -1.535038 2.1541656 2.216305 2.344827 0.7803539 1.3822233 0.08096948 0.06735000 0.043250 0.097350 0.054100 1.000000e+00 1.147618e-16 TRUE TRUE
MSTRG.5102.2 ENSG00000172890 No_inf pgKDN_inf NADSYN1 protein_coding   45.42551 71.56721 24.68916 16.30331 0.3784415 -1.535038 0.9604663 0.000000 1.874312 0.0000000 1.2133826 7.55789412 0.02976667 0.000000 0.073800 0.073800 2.768526e-01 1.147618e-16 FALSE TRUE
MSTRG.5102.3 ENSG00000172890 No_inf pgKDN_inf NADSYN1 protein_coding   45.42551 71.56721 24.68916 16.30331 0.3784415 -1.535038 4.9020785 8.009272 2.221147 0.3697110 0.9111961 -1.84568553 0.10770833 0.135525 0.089250 -0.046275 8.228313e-01 1.147618e-16 TRUE TRUE
MSTRG.5102.31 ENSG00000172890 No_inf pgKDN_inf NADSYN1 protein_coding   45.42551 71.56721 24.68916 16.30331 0.3784415 -1.535038 15.5045108 36.979623 0.000000 15.0639323 0.0000000 -11.85290490 0.18979167 0.422525 0.000000 -0.422525 7.375992e-02 1.147618e-16   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172890 E001 0.3724725 0.0167136745 8.927171e-01   11 71453109 71453201 93 + 0.115 0.144 0.377
ENSG00000172890 E002 0.3724725 0.0167136745 8.927171e-01   11 71453202 71453202 1 + 0.115 0.144 0.377
ENSG00000172890 E003 0.9901199 0.0132365260 9.146894e-01 0.973093890 11 71453203 71453208 6 + 0.281 0.298 0.114
ENSG00000172890 E004 0.9901199 0.0132365260 9.146894e-01 0.973093890 11 71453209 71453210 2 + 0.281 0.298 0.114
ENSG00000172890 E005 0.9901199 0.0132365260 9.146894e-01 0.973093890 11 71453211 71453212 2 + 0.281 0.298 0.114
ENSG00000172890 E006 1.4876212 0.0086246927 6.686552e-01 0.862035320 11 71453213 71453216 4 + 0.345 0.411 0.377
ENSG00000172890 E007 2.1228641 0.0063973401 1.706318e-01 0.442942361 11 71453217 71453230 14 + 0.345 0.552 1.077
ENSG00000172890 E008 2.7305704 0.0050329866 4.670116e-01 0.735597701 11 71453231 71453240 10 + 0.495 0.598 0.476
ENSG00000172890 E009 5.4410225 0.0026135133 6.841496e-01 0.869235516 11 71453241 71453355 115 + 0.768 0.814 0.184
ENSG00000172890 E010 3.3180969 0.0043672001 5.961580e-01 0.822489170 11 71453356 71453381 26 + 0.667 0.598 -0.301
ENSG00000172890 E011 4.1620110 0.0034430100 2.150359e-01 0.500679866 11 71455110 71455124 15 + 0.790 0.639 -0.623
ENSG00000172890 E012 8.2422424 0.0017339600 5.179758e-01 0.773293252 11 71455125 71455170 46 + 0.992 0.929 -0.233
ENSG00000172890 E013 0.1170040 0.0117755700 3.437888e-01   11 71455171 71455460 290 + 0.115 0.000 -8.758
ENSG00000172890 E014 15.5983059 0.0010246146 1.068582e-01 0.342500521 11 71458428 71458544 117 + 1.277 1.159 -0.418
ENSG00000172890 E015 0.0000000       11 71458545 71458556 12 +      
ENSG00000172890 E016 0.8712934 0.0131384494 5.541778e-01 0.797019422 11 71458557 71459056 500 + 0.206 0.298 0.699
ENSG00000172890 E017 1.2428230 0.0110975975 5.428276e-01 0.789983221 11 71459675 71460040 366 + 0.281 0.377 0.599
ENSG00000172890 E018 1.9774447 0.0071469264 8.797160e-01 0.959428235 11 71460041 71460213 173 + 0.451 0.473 0.114
ENSG00000172890 E019 0.6255163 0.0148588940 3.681071e-01 0.656634162 11 71460722 71460947 226 + 0.115 0.253 1.377
ENSG00000172890 E020 7.6995741 0.0248244561 4.832608e-02 0.216354164 11 71463432 71463485 54 + 1.054 0.827 -0.853
ENSG00000172890 E021 10.3553985 0.0025695362 1.796220e-03 0.023513913 11 71464053 71464142 90 + 1.193 0.919 -0.999
ENSG00000172890 E022 0.6152580 0.0143274383 9.769980e-01 0.996375381 11 71464143 71464508 366 + 0.206 0.202 -0.038
ENSG00000172890 E023 0.0000000       11 71466724 71466766 43 +      
ENSG00000172890 E024 7.8289218 0.0212143901 1.372155e-01 0.394319866 11 71472449 71472500 52 + 1.030 0.864 -0.623
ENSG00000172890 E025 9.0606253 0.0015298312 6.635090e-02 0.259448217 11 71473278 71473366 89 + 1.088 0.919 -0.623
ENSG00000172890 E026 8.4313521 0.0042591561 2.047059e-02 0.128753443 11 71473569 71473662 94 + 1.088 0.864 -0.833
ENSG00000172890 E027 4.4158065 0.0033115556 3.454430e-01 0.636461020 11 71473663 71473686 24 + 0.790 0.676 -0.463
ENSG00000172890 E028 12.0418003 0.0279867141 3.829285e-01 0.669070489 11 71474395 71474526 132 + 1.157 1.066 -0.328
ENSG00000172890 E029 1.6337001 0.1909174906 1.348989e-01 0.390462542 11 71474527 71474758 232 + 0.206 0.501 1.837
ENSG00000172890 E030 10.3582185 0.0211578314 6.716686e-03 0.061306102 11 71474759 71475622 864 + 0.831 1.134 1.129
ENSG00000172890 E031 1.7148600 0.0079159060 4.268700e-01 0.705442015 11 71476033 71476200 168 + 0.495 0.377 -0.623
ENSG00000172890 E032 22.7403988 0.0106276662 5.780715e-01 0.811480768 11 71476201 71477344 1144 + 1.336 1.378 0.147
ENSG00000172890 E033 4.3202740 0.0470684704 8.174756e-01 0.933608789 11 71477345 71477438 94 + 0.694 0.727 0.137
ENSG00000172890 E034 6.6346208 0.0044387887 4.584881e-01 0.730411981 11 71478395 71478398 4 + 0.919 0.840 -0.301
ENSG00000172890 E035 11.0552586 0.0012829378 2.367324e-01 0.525659955 11 71478399 71478469 71 + 1.129 1.028 -0.366
ENSG00000172890 E036 33.3876802 0.0044363918 1.128529e-02 0.087088425 11 71478470 71479293 824 + 1.423 1.574 0.516
ENSG00000172890 E037 54.6733706 0.0006009906 8.053918e-05 0.001983470 11 71479294 71480148 855 + 1.620 1.788 0.568
ENSG00000172890 E038 2.4963405 0.0065325771 1.801213e-01 0.455552619 11 71480149 71480151 3 + 0.401 0.598 0.962
ENSG00000172890 E039 5.8955754 0.0086786033 1.363541e-03 0.019022556 11 71480152 71480218 67 + 0.535 0.939 1.662
ENSG00000172890 E040 6.1481882 0.0042800761 5.639829e-04 0.009592511 11 71480219 71480274 56 + 0.535 0.958 1.734
ENSG00000172890 E041 14.5407871 0.0010179595 6.346614e-01 0.843861560 11 71480755 71480810 56 + 1.201 1.165 -0.129
ENSG00000172890 E042 15.5168997 0.0151961872 4.790547e-01 0.744983496 11 71480811 71480879 69 + 1.241 1.182 -0.208
ENSG00000172890 E043 1.4587934 0.3531954336 4.114331e-01 0.693119069 11 71480880 71481355 476 + 0.495 0.298 -1.109
ENSG00000172890 E044 13.8953971 0.0201358044 2.528021e-01 0.544121640 11 71481356 71481404 49 + 1.225 1.115 -0.393
ENSG00000172890 E045 2.1064677 0.0080404347 7.309708e-01 0.893158058 11 71481405 71481922 518 + 0.451 0.501 0.251
ENSG00000172890 E046 23.8459827 0.0007356310 9.022083e-02 0.311989507 11 71481923 71482000 78 + 1.443 1.341 -0.355
ENSG00000172890 E047 19.0848848 0.0007432010 4.159166e-01 0.695955803 11 71482001 71482025 25 + 1.323 1.268 -0.192
ENSG00000172890 E048 0.0000000       11 71482723 71482848 126 +      
ENSG00000172890 E049 36.2214394 0.0003862371 3.211899e-01 0.614275832 11 71482849 71483017 169 + 1.587 1.538 -0.168
ENSG00000172890 E050 33.5814729 0.0170302533 9.987120e-01 1.000000000 11 71484312 71484447 136 + 1.525 1.526 0.001
ENSG00000172890 E051 2.6194466 0.0054757753 1.349034e-01 0.390462542 11 71484448 71485541 1094 + 0.401 0.619 1.055
ENSG00000172890 E052 30.9728638 0.0005281001 9.827511e-01 0.998690264 11 71485542 71485648 107 + 1.492 1.491 -0.005
ENSG00000172890 E053 30.0933302 0.0004866908 3.065594e-02 0.164730230 11 71490845 71490976 132 + 1.548 1.432 -0.399
ENSG00000172890 E054 21.2516904 0.0180822089 1.466739e-01 0.407705554 11 71491834 71491903 70 + 1.403 1.287 -0.406
ENSG00000172890 E055 1.2434159 0.0153405403 5.437242e-01 0.790539037 11 71496435 71497482 1048 + 0.281 0.377 0.599
ENSG00000172890 E056 10.5981001 0.0155561907 6.717593e-01 0.863910258 11 71497483 71497486 4 + 1.077 1.036 -0.149
ENSG00000172890 E057 14.0448727 0.0013750111 5.553585e-01 0.797930308 11 71497487 71497504 18 + 1.193 1.147 -0.164
ENSG00000172890 E058 35.4040435 0.0004361429 8.089372e-01 0.929444482 11 71497505 71497611 107 + 1.555 1.543 -0.042
ENSG00000172890 E059 26.6922000 0.0005327372 6.665918e-01 0.861339079 11 71498352 71498401 50 + 1.413 1.438 0.085
ENSG00000172890 E060 40.5448502 0.0003945047 4.776679e-01 0.743900635 11 71498402 71498528 127 + 1.584 1.617 0.114
ENSG00000172890 E061 4.6187312 0.0031991904 5.517365e-02 0.233996689 11 71498529 71500035 1507 + 0.572 0.814 1.014
ENSG00000172890 E062 25.3809482 0.0006746413 4.873660e-01 0.750901297 11 71501302 71501426 125 + 1.433 1.392 -0.142
ENSG00000172890 E063 9.2415136 0.0014438465 7.311377e-01 0.893224500 11 71501427 71501816 390 + 1.018 0.986 -0.118
ENSG00000172890 E064 1.4917428 0.1873088307 7.689677e-01 0.910626835 11 71503090 71503303 214 + 0.346 0.411 0.376
ENSG00000172890 E065 0.6169571 0.0143367351 9.774170e-01 0.996591478 11 71503545 71503741 197 + 0.206 0.202 -0.038
ENSG00000172890 E066 2.0130961 0.0084122550 1.849174e-02 0.120349160 11 71503864 71504065 202 + 0.206 0.575 2.184
ENSG00000172890 E067 7.0347067 0.0021016324 4.208899e-05 0.001154056 11 71504066 71505510 1445 + 0.535 1.020 1.962
ENSG00000172890 E068 1.7601124 0.0111837345 4.194083e-02 0.199280813 11 71505511 71505567 57 + 0.206 0.527 1.962
ENSG00000172890 E069 3.5006226 0.0288614719 6.200119e-02 0.250120769 11 71505568 71505874 307 + 0.451 0.727 1.251
ENSG00000172890 E070 0.0000000       11 71521090 71521097 8 +      
ENSG00000172890 E071 0.7529048 0.0133864464 2.366152e-01 0.525536487 11 71521098 71521204 107 + 0.115 0.298 1.699
ENSG00000172890 E072 0.3719991 0.0166605098 8.928331e-01   11 71521623 71521654 32 + 0.115 0.144 0.377
ENSG00000172890 E073 0.0000000       11 71523996 71524107 112 +      

Help

Please Click HERE to learn more details about the results from DEXseq.