ENSG00000172922

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000308418 ENSG00000172922 No_inf pgKDN_inf RNASEH2C protein_coding protein_coding 47.19294 43.42977 49.74387 2.571254 3.606133 0.1957925 0.7828844 2.348653 0.000000 0.9019555 0.000000 -7.8818194 0.01905833 0.057175 0.000000 -0.057175 0.04206251 0.0009933924 FALSE TRUE
ENST00000530192 ENSG00000172922 No_inf pgKDN_inf RNASEH2C protein_coding retained_intron 47.19294 43.42977 49.74387 2.571254 3.606133 0.1957925 19.2919839 16.707160 18.811449 2.9403061 2.591906 0.1710480 0.40428333 0.379900 0.374275 -0.005625 1.00000000 0.0009933924 FALSE TRUE
ENST00000531596 ENSG00000172922 No_inf pgKDN_inf RNASEH2C protein_coding nonsense_mediated_decay 47.19294 43.42977 49.74387 2.571254 3.606133 0.1957925 1.6795723 4.264188 0.000000 1.4776348 0.000000 -8.7395066 0.03873333 0.100850 0.000000 -0.100850 0.01841273 0.0009933924 TRUE TRUE
ENST00000533698 ENSG00000172922 No_inf pgKDN_inf RNASEH2C protein_coding retained_intron 47.19294 43.42977 49.74387 2.571254 3.606133 0.1957925 18.0647542 13.653937 24.009863 1.6400437 2.714043 0.8138547 0.38152500 0.316700 0.484800 0.168100 0.27594098 0.0009933924 TRUE FALSE
ENST00000644142 ENSG00000172922 No_inf pgKDN_inf RNASEH2C protein_coding nonsense_mediated_decay 47.19294 43.42977 49.74387 2.571254 3.606133 0.1957925 2.8893868 1.644562 1.832573 1.6445625 1.098879 0.1552719 0.06181667 0.036100 0.040250 0.004150 0.83059172 0.0009933924 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172922 E001 0.4989795 0.0288415708 3.793771e-01   11 65714005 65715000 996 - 0.099 0.230 1.444
ENSG00000172922 E002 0.4997349 0.0215954344 3.785135e-01   11 65715001 65715031 31 - 0.099 0.230 1.444
ENSG00000172922 E003 0.6176177 0.0219147498 7.498312e-01 9.014220e-01 11 65715032 65715079 48 - 0.180 0.230 0.444
ENSG00000172922 E004 2.8697892 0.0078879961 4.103242e-02 1.966263e-01 11 65715080 65715317 238 - 0.405 0.696 1.362
ENSG00000172922 E005 1.3690134 0.0189591268 1.819975e-01 4.579766e-01 11 65715933 65716017 85 - 0.248 0.457 1.274
ENSG00000172922 E006 3.6350677 0.0885712217 7.416191e-03 6.566818e-02 11 65717245 65717662 418 - 0.359 0.819 2.121
ENSG00000172922 E007 0.3717469 0.0165076458 6.567185e-01   11 65717663 65717672 10 - 0.099 0.166 0.859
ENSG00000172922 E008 0.7527786 0.0183524768 1.232810e-01 3.717127e-01 11 65717673 65717708 36 - 0.099 0.336 2.181
ENSG00000172922 E009 0.7622843 0.0136149494 1.362763e-02 9.827421e-02 11 65717709 65717714 6 - 0.000 0.380 12.613
ENSG00000172922 E010 1.5058771 0.0102908832 2.772756e-02 1.553562e-01 11 65717715 65717737 23 - 0.180 0.523 2.181
ENSG00000172922 E011 8.0277531 0.0019468439 4.344811e-07 2.177816e-05 11 65717738 65717893 156 - 0.583 1.126 2.128
ENSG00000172922 E012 21.9203963 0.0006543617 8.625076e-09 6.210746e-07 11 65717894 65718535 642 - 1.117 1.492 1.316
ENSG00000172922 E013 0.0000000       11 65718536 65718769 234 -      
ENSG00000172922 E014 0.7348701 0.0143574504 8.946682e-01 9.651958e-01 11 65718770 65718822 53 - 0.248 0.230 -0.141
ENSG00000172922 E015 1.1058644 0.0110749165 8.665165e-01 9.539969e-01 11 65718823 65719156 334 - 0.307 0.336 0.181
ENSG00000172922 E016 1.1135119 0.0115895991 4.044308e-01 6.871556e-01 11 65719157 65719680 524 - 0.248 0.380 0.859
ENSG00000172922 E017 8.7103210 0.0018015234 9.075712e-01 9.706659e-01 11 65719681 65719720 40 - 0.988 0.983 -0.019
ENSG00000172922 E018 27.5028164 0.0005252878 9.968867e-02 3.298739e-01 11 65719721 65719809 89 - 1.496 1.414 -0.282
ENSG00000172922 E019 0.7342435 0.0135428288 8.938792e-01 9.649124e-01 11 65719810 65720044 235 - 0.248 0.230 -0.141
ENSG00000172922 E020 22.3362038 0.0006360436 3.711129e-02 1.855294e-01 11 65720045 65720053 9 - 1.427 1.309 -0.410
ENSG00000172922 E021 43.8552627 0.0003274303 9.386715e-03 7.711598e-02 11 65720054 65720164 111 - 1.702 1.601 -0.342
ENSG00000172922 E022 0.5082326 0.0218869672 5.982104e-02 2.452967e-01 11 65720165 65720241 77 - 0.000 0.286 12.089
ENSG00000172922 E023 61.9126975 0.0011850571 4.973692e-02 2.200222e-01 11 65720242 65720417 176 - 1.830 1.768 -0.209
ENSG00000172922 E024 6.2886490 0.0023733199 3.527166e-03 3.893436e-02 11 65720418 65720586 169 - 1.000 0.696 -1.183
ENSG00000172922 E025 28.2757589 0.0144500195 5.466698e-01 7.923487e-01 11 65720587 65720818 232 - 1.485 1.448 -0.127

Help

Please Click HERE to learn more details about the results from DEXseq.