ENSG00000172936

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000417037 ENSG00000172936 No_inf pgKDN_inf MYD88 protein_coding protein_coding 30.79792 30.1932 32.81391 0.7644538 1.123532 0.1200457 1.595730 0.6517409 1.184171 0.6517409 1.1841714 0.8516714 0.05310833 0.021700 0.034975 0.013275 1.000000000 0.002925105 FALSE TRUE
ENST00000463956 ENSG00000172936 No_inf pgKDN_inf MYD88 protein_coding protein_coding_CDS_not_defined 30.79792 30.1932 32.81391 0.7644538 1.123532 0.1200457 3.593795 7.8255041 2.004659 2.9752224 2.0046590 -1.9594904 0.11556667 0.253925 0.062025 -0.191900 0.231751326 0.002925105 FALSE TRUE
ENST00000481122 ENSG00000172936 No_inf pgKDN_inf MYD88 protein_coding protein_coding_CDS_not_defined 30.79792 30.1932 32.81391 0.7644538 1.123532 0.1200457 1.071076 3.2132290 0.000000 3.2132290 0.0000000 -8.3323629 0.03660000 0.109800 0.000000 -0.109800 0.851408171 0.002925105 FALSE TRUE
ENST00000650112 ENSG00000172936 No_inf pgKDN_inf MYD88 protein_coding protein_coding 30.79792 30.1932 32.81391 0.7644538 1.123532 0.1200457 2.379297 4.1421053 2.373120 2.5130710 2.3731203 -0.8009913 0.07576667 0.139675 0.067500 -0.072175 0.811022857 0.002925105 FALSE TRUE
ENST00000650905 ENSG00000172936 No_inf pgKDN_inf MYD88 protein_coding protein_coding 30.79792 30.1932 32.81391 0.7644538 1.123532 0.1200457 13.395960 2.3129361 18.547689 2.3129361 2.3426168 2.9979957 0.43613333 0.079575 0.570375 0.490800 0.002925105 0.002925105 FALSE TRUE
ENST00000651800 ENSG00000172936 No_inf pgKDN_inf MYD88 protein_coding protein_coding 30.79792 30.1932 32.81391 0.7644538 1.123532 0.1200457 1.344482 2.8573783 1.176067 2.8573783 1.1760671 -1.2735467 0.04098333 0.088200 0.034750 -0.053450 1.000000000 0.002925105 FALSE TRUE
ENST00000652213 ENSG00000172936 No_inf pgKDN_inf MYD88 protein_coding protein_coding 30.79792 30.1932 32.81391 0.7644538 1.123532 0.1200457 2.038977 2.6708140 2.459970 1.5795961 0.9281847 -0.1181777 0.06690000 0.090275 0.076950 -0.013325 0.880337645 0.002925105 FALSE TRUE
ENST00000652590 ENSG00000172936 No_inf pgKDN_inf MYD88 protein_coding retained_intron 30.79792 30.1932 32.81391 0.7644538 1.123532 0.1200457 2.273801 3.7476458 1.222106 1.4602673 1.2221060 -1.6087027 0.07495833 0.124650 0.036100 -0.088550 0.374506302 0.002925105 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172936 E001 0.0000000       3 38138478 38138551 74 +      
ENSG00000172936 E002 0.1176306 1.177544e-02 0.521986406   3 38138552 38138632 81 + 0.096 0.000 -9.891
ENSG00000172936 E003 0.1176306 1.177544e-02 0.521986406   3 38138633 38138634 2 + 0.096 0.000 -11.753
ENSG00000172936 E004 0.3714000 1.680434e-02 0.602659614   3 38138635 38138650 16 + 0.096 0.171 0.956
ENSG00000172936 E005 0.6261768 4.645678e-02 0.191928899 0.47169944 3 38138651 38138656 6 + 0.096 0.293 1.956
ENSG00000172936 E006 0.7448800 2.816434e-02 0.440104362 0.71590628 3 38138657 38138660 4 + 0.175 0.293 0.956
ENSG00000172936 E007 1.2270492 1.327449e-01 0.961308920 0.99148828 3 38138661 38138670 10 + 0.351 0.344 -0.044
ENSG00000172936 E008 8.2989609 6.098433e-02 0.443738790 0.71843570 3 38138671 38138765 95 + 1.019 0.916 -0.385
ENSG00000172936 E009 25.6743991 5.281441e-04 0.004819887 0.04823851 3 38138766 38139028 263 + 1.503 1.342 -0.555
ENSG00000172936 E010 1.5157877 1.750729e-01 0.015313341 0.10663779 3 38139029 38139151 123 + 0.096 0.563 3.416
ENSG00000172936 E011 1.0068955 4.382633e-02 0.034188617 0.17640485 3 38139152 38139272 121 + 0.096 0.429 2.764
ENSG00000172936 E012 5.0781791 2.731439e-03 0.052816195 0.22843638 3 38139273 38139665 393 + 0.651 0.876 0.904
ENSG00000172936 E013 0.9860340 5.087192e-02 0.514633707 0.77113559 3 38139666 38139780 115 + 0.242 0.344 0.694
ENSG00000172936 E014 0.9966393 9.335277e-02 0.194891065 0.47493470 3 38139781 38139863 83 + 0.175 0.389 1.542
ENSG00000172936 E015 18.1020062 1.790637e-03 0.502400529 0.76207870 3 38139864 38139998 135 + 1.304 1.258 -0.161
ENSG00000172936 E016 4.0852300 3.995031e-03 0.140916305 0.39935182 3 38139999 38140387 389 + 0.600 0.783 0.764
ENSG00000172936 E017 21.5514769 6.645972e-04 0.023885994 0.14146495 3 38140388 38140549 162 + 1.421 1.281 -0.487
ENSG00000172936 E018 7.7806951 1.992444e-03 0.062002322 0.25012077 3 38140550 38140568 19 + 1.029 0.847 -0.685
ENSG00000172936 E019 1.8575106 8.469254e-03 0.219504456 0.50621086 3 38140569 38140592 24 + 0.351 0.533 0.956
ENSG00000172936 E020 7.0421259 2.150596e-03 0.061243052 0.24851427 3 38140593 38140756 164 + 0.794 0.986 0.734
ENSG00000172936 E021 26.7662638 5.348607e-04 0.381511383 0.66791427 3 38140757 38140848 92 + 1.417 1.466 0.169
ENSG00000172936 E022 319.9011883 8.870054e-05 0.380747176 0.66718276 3 38141132 38143024 1893 + 2.502 2.510 0.027

Help

Please Click HERE to learn more details about the results from DEXseq.