ENSG00000172943

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000338154 ENSG00000172943 No_inf pgKDN_inf PHF8 protein_coding protein_coding 15.20222 19.38306 14.54679 4.754385 1.327779 -0.4138489 0.9171411 0.000000 1.9112165 0.0000000 0.8280592 7.58587626 0.07042500 0.000000 0.140525 0.140525 0.0409473886 0.0005306287 FALSE TRUE
ENST00000338946 ENSG00000172943 No_inf pgKDN_inf PHF8 protein_coding protein_coding 15.20222 19.38306 14.54679 4.754385 1.327779 -0.4138489 2.1601411 1.600337 2.7266954 0.6879142 1.0001235 0.76507222 0.15991667 0.103525 0.190900 0.087375 0.8549725922 0.0005306287 FALSE TRUE
ENST00000448003 ENSG00000172943 No_inf pgKDN_inf PHF8 protein_coding protein_coding 15.20222 19.38306 14.54679 4.754385 1.327779 -0.4138489 0.5051716 0.000000 1.5155148 0.0000000 1.5155148 7.25315241 0.03130833 0.000000 0.093925 0.093925 0.8332318805 0.0005306287 FALSE FALSE
ENST00000687283 ENSG00000172943 No_inf pgKDN_inf PHF8 protein_coding retained_intron 15.20222 19.38306 14.54679 4.754385 1.327779 -0.4138489 0.9532501 2.492003 0.0000000 0.2066402 0.0000000 -7.96693991 0.06215000 0.154650 0.000000 -0.154650 0.0005306287 0.0005306287 FALSE TRUE
ENST00000687764 ENSG00000172943 No_inf pgKDN_inf PHF8 protein_coding nonsense_mediated_decay 15.20222 19.38306 14.54679 4.754385 1.327779 -0.4138489 1.4777291 2.510374 0.7182431 0.7809963 0.4301242 -1.79114600 0.10434167 0.163425 0.045950 -0.117475 0.6192198194 0.0005306287 TRUE TRUE
MSTRG.30021.1 ENSG00000172943 No_inf pgKDN_inf PHF8 protein_coding   15.20222 19.38306 14.54679 4.754385 1.327779 -0.4138489 3.5904191 3.679249 3.8509915 0.4047675 0.5612093 0.06564437 0.25295833 0.208725 0.275025 0.066300 0.8347278747 0.0005306287 FALSE TRUE
MSTRG.30021.17 ENSG00000172943 No_inf pgKDN_inf PHF8 protein_coding   15.20222 19.38306 14.54679 4.754385 1.327779 -0.4138489 3.0168753 5.704716 2.5707623 3.9379448 1.5027029 -1.14688455 0.14325833 0.206725 0.165900 -0.040825 1.0000000000 0.0005306287 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000172943 E001 0.7617499 0.0133098262 0.016575884 0.11211484 X 53936559 53936675 117 - 0.000 0.371 12.673
ENSG00000172943 E002 0.1271363 0.0124565890 0.640986022   X 53936676 53936679 4 - 0.000 0.088 12.832
ENSG00000172943 E003 0.8616965 0.0128452585 0.886720074 0.96213985 X 53936680 53936693 14 - 0.255 0.279 0.176
ENSG00000172943 E004 53.0380410 0.0004452503 0.389605954 0.67530277 X 53936694 53937497 804 - 1.707 1.746 0.131
ENSG00000172943 E005 39.1093338 0.0117574268 0.743004730 0.89839494 X 53937498 53938059 562 - 1.585 1.611 0.089
ENSG00000172943 E006 36.5167443 0.0007154154 0.604938901 0.82777885 X 53938060 53939161 1102 - 1.554 1.584 0.103
ENSG00000172943 E007 8.5595213 0.0430853595 0.461720039 0.73231609 X 53939162 53939246 85 - 1.024 0.938 -0.321
ENSG00000172943 E008 13.6105788 0.0019065495 0.647993083 0.85137293 X 53940180 53940368 189 - 1.179 1.148 -0.109
ENSG00000172943 E009 12.3822932 0.0016131601 0.019178370 0.12358019 X 53940369 53940516 148 - 1.002 1.201 0.718
ENSG00000172943 E010 1.3580606 0.0102444340 0.541307062 0.78900749 X 53942618 53943255 638 - 0.315 0.411 0.569
ENSG00000172943 E011 1.6319108 0.0085145831 0.021942687 0.13445420 X 53943256 53943402 147 - 0.185 0.541 2.221
ENSG00000172943 E012 11.7348751 0.0011961722 0.129944790 0.38240038 X 53944134 53944243 110 - 1.024 1.155 0.474
ENSG00000172943 E013 0.1272623 0.0123625410 0.641150599   X 53944244 53944564 321 - 0.000 0.088 12.832
ENSG00000172943 E014 8.6913951 0.0276322600 0.465621907 0.73457314 X 53962844 53962939 96 - 1.024 0.949 -0.279
ENSG00000172943 E015 0.0000000       X 53962940 53963049 110 -      
ENSG00000172943 E016 16.8583227 0.0008050604 0.055467761 0.23465539 X 53984914 53985227 314 - 1.315 1.188 -0.448
ENSG00000172943 E017 8.9854397 0.0393238151 0.002937473 0.03399778 X 53985228 53985744 517 - 0.742 1.127 1.455
ENSG00000172943 E018 1.8931101 0.2482577995 0.020394385 0.12848391 X 53985745 53985784 40 - 0.102 0.618 3.568
ENSG00000172943 E019 2.2372615 0.1408182005 0.225512984 0.51330733 X 53985785 53985815 31 - 0.367 0.594 1.140
ENSG00000172943 E020 6.6365542 0.0024523670 0.869665275 0.95513414 X 53985816 53985848 33 - 0.868 0.890 0.083
ENSG00000172943 E021 8.8242002 0.0015411168 0.605280987 0.82797060 X 53985849 53985906 58 - 1.013 0.970 -0.159
ENSG00000172943 E022 8.0302825 0.0039600893 0.256666084 0.54876035 X 53985907 53985949 43 - 0.884 1.001 0.439
ENSG00000172943 E023 9.1005507 0.0398040036 0.966463436 0.99320222 X 53987078 53987163 86 - 1.002 1.001 -0.005
ENSG00000172943 E024 4.9067614 0.0369684079 0.655545125 0.85558579 X 53987766 53987786 21 - 0.801 0.741 -0.239
ENSG00000172943 E025 10.7715303 0.0273286479 0.406317808 0.68904366 X 53987787 53987944 158 - 1.113 1.029 -0.305
ENSG00000172943 E026 5.1429730 0.0040404759 0.569516504 0.80642692 X 53992736 53992793 58 - 0.818 0.758 -0.239
ENSG00000172943 E027 3.8989941 0.0099697660 0.241651722 0.53135413 X 53992794 53992801 8 - 0.762 0.619 -0.601
ENSG00000172943 E028 4.7518753 0.0030568649 0.178422567 0.45327568 X 53992802 53992839 38 - 0.836 0.684 -0.611
ENSG00000172943 E029 0.1271363 0.0124565890 0.640986022   X 53992840 53993009 170 - 0.000 0.088 12.832
ENSG00000172943 E030 10.0480884 0.0018372680 0.559742357 0.80065195 X 53993601 53993903 303 - 1.066 1.020 -0.168
ENSG00000172943 E031 0.4979097 0.0153587411 0.411742716   X 53995131 53995205 75 - 0.102 0.224 1.346
ENSG00000172943 E032 5.5042726 0.0056841579 0.465334349 0.73439875 X 53995693 53995782 90 - 0.852 0.775 -0.303
ENSG00000172943 E033 0.0000000       X 53998155 53998286 132 -      
ENSG00000172943 E034 0.1176306 0.0117484252 0.450008687   X 53999487 53999869 383 - 0.102 0.000 -13.896
ENSG00000172943 E035 5.1375535 0.0056604492 0.386787964 0.67263757 X 53999870 53999961 92 - 0.836 0.741 -0.376
ENSG00000172943 E036 6.6703393 0.0022821641 0.007452980 0.06590737 X 54002155 54002261 107 - 1.013 0.741 -1.046
ENSG00000172943 E037 5.3680153 0.0027187390 0.236161799 0.52541878 X 54002595 54002682 88 - 0.868 0.741 -0.502
ENSG00000172943 E038 6.9991017 0.0036677312 0.994726259 1.00000000 X 54011122 54011284 163 - 0.898 0.902 0.015
ENSG00000172943 E039 0.0000000       X 54013590 54013650 61 -      
ENSG00000172943 E040 11.1389300 0.0191647104 0.429268821 0.70758453 X 54014377 54014563 187 - 1.122 1.047 -0.270
ENSG00000172943 E041 7.9751917 0.0021745220 0.733898682 0.89434885 X 54016595 54016736 142 - 0.966 0.938 -0.106
ENSG00000172943 E042 3.0746863 0.0166378561 0.884717701 0.96116819 X 54017661 54017736 76 - 0.594 0.618 0.109
ENSG00000172943 E043 2.0866011 0.0075889769 0.903852711 0.96906906 X 54017737 54017769 33 - 0.495 0.481 -0.069
ENSG00000172943 E044 1.2156573 0.0102508246 0.365793922 0.65428745 X 54017770 54017770 1 - 0.414 0.279 -0.824
ENSG00000172943 E045 1.3342955 0.0098669665 0.234520362 0.52360066 X 54017771 54017778 8 - 0.457 0.279 -1.046
ENSG00000172943 E046 2.4338980 0.0220469211 0.219640012 0.50624298 X 54017779 54017821 43 - 0.622 0.448 -0.824
ENSG00000172943 E047 5.3698275 0.0436075581 0.220872691 0.50786783 X 54022259 54022367 109 - 0.884 0.723 -0.635
ENSG00000172943 E048 4.3017055 0.0033754445 0.987064894 0.99961988 X 54022758 54022843 86 - 0.721 0.723 0.009
ENSG00000172943 E049 0.0000000       X 54039630 54040072 443 -      
ENSG00000172943 E050 5.0449190 0.0029037670 0.831536741 0.93921867 X 54042631 54042809 179 - 0.762 0.791 0.115
ENSG00000172943 E051 1.3619633 0.0556683361 0.567573904 0.80532253 X 54042810 54042820 11 - 0.315 0.411 0.568
ENSG00000172943 E052 0.2536433 0.0161081762 0.309030250   X 54042821 54042836 16 - 0.000 0.162 13.748
ENSG00000172943 E053 0.0000000       X 54042837 54042907 71 -      
ENSG00000172943 E054 0.1265070 0.0123120482 0.641125696   X 54042908 54043057 150 - 0.000 0.088 12.832
ENSG00000172943 E055 0.1265070 0.0123120482 0.641125696   X 54043058 54043110 53 - 0.000 0.088 12.832
ENSG00000172943 E056 0.3611417 0.0165640071 0.479328146   X 54043111 54043194 84 - 0.185 0.088 -1.239
ENSG00000172943 E057 2.0939433 0.0631298220 0.774086426 0.91318460 X 54043762 54043811 50 - 0.457 0.512 0.275
ENSG00000172943 E058 7.2431534 0.0099193882 0.974342829 0.99538773 X 54043812 54044473 662 - 0.913 0.914 0.006
ENSG00000172943 E059 0.1265070 0.0123120482 0.641125696   X 54044875 54044949 75 - 0.000 0.088 12.832
ENSG00000172943 E060 0.2447669 0.0164380463 0.890690601   X 54044950 54045249 300 - 0.102 0.088 -0.239
ENSG00000172943 E061 0.0000000       X 54048905 54048958 54 -      

Help

Please Click HERE to learn more details about the results from DEXseq.