ENSG00000173020

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000308595 ENSG00000173020 No_inf pgKDN_inf GRK2 protein_coding protein_coding 119.137 156.3437 98.12558 4.210185 2.200936 -0.6719653 70.011743 75.84880 68.575614 1.8655819 0.7253893 -0.1454105 0.60927500 0.486625 0.700375 0.213750 0.0001034548 0.0001034548 FALSE TRUE
ENST00000524899 ENSG00000173020 No_inf pgKDN_inf GRK2 protein_coding protein_coding_CDS_not_defined 119.137 156.3437 98.12558 4.210185 2.200936 -0.6719653 16.580269 24.39720 9.581273 3.8564750 2.0078847 -1.3475127 0.13474167 0.154525 0.096800 -0.057725 0.5200076444 0.0001034548 FALSE FALSE
MSTRG.5016.14 ENSG00000173020 No_inf pgKDN_inf GRK2 protein_coding   119.137 156.3437 98.12558 4.210185 2.200936 -0.6719653 8.681628 19.41569 5.163665 0.8832897 2.9826050 -1.9087072 0.06413333 0.124225 0.053175 -0.071050 0.4104635867 0.0001034548 FALSE TRUE
MSTRG.5016.6 ENSG00000173020 No_inf pgKDN_inf GRK2 protein_coding   119.137 156.3437 98.12558 4.210185 2.200936 -0.6719653 5.387773 10.24702 1.026876 2.3999357 1.0268758 -3.3062965 0.04138333 0.066000 0.010075 -0.055925 0.0451890107 0.0001034548 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000173020 E001 4.0112011 0.0034981259 1.061292e-02 8.350920e-02 11 67266408 67266472 65 + 0.858 0.545 -1.312
ENSG00000173020 E002 4.6471347 0.0035019548 7.769400e-02 2.852320e-01 11 67266473 67266480 8 + 0.858 0.650 -0.842
ENSG00000173020 E003 52.5398159 0.0036586783 4.488049e-02 2.070791e-01 11 67266481 67266812 332 + 1.772 1.674 -0.330
ENSG00000173020 E004 0.3806233 0.0158349789 2.335438e-01   11 67270938 67271008 71 + 0.000 0.198 10.313
ENSG00000173020 E005 11.5373213 0.0053176185 3.119766e-05 8.931076e-04 11 67276537 67277271 735 + 0.776 1.194 1.558
ENSG00000173020 E006 46.3306146 0.0003162745 3.874145e-03 4.151768e-02 11 67277272 67277348 77 + 1.736 1.607 -0.437
ENSG00000173020 E007 53.0401036 0.0003115037 3.131266e-02 1.670432e-01 11 67279200 67279273 74 + 1.772 1.681 -0.306
ENSG00000173020 E008 56.0690000 0.0003532572 2.218820e-01 5.091251e-01 11 67279418 67279473 56 + 1.772 1.721 -0.171
ENSG00000173020 E009 55.0472841 0.0084671784 3.683221e-02 1.848087e-01 11 67279474 67279519 46 + 1.803 1.687 -0.393
ENSG00000173020 E010 66.1247433 0.0005189825 5.525160e-01 7.960516e-01 11 67279626 67279700 75 + 1.826 1.802 -0.078
ENSG00000173020 E011 55.9989946 0.0003784091 3.795001e-01 6.662160e-01 11 67279839 67279900 62 + 1.763 1.726 -0.124
ENSG00000173020 E012 2.0153008 0.0069857164 2.281868e-02 1.376963e-01 11 67280194 67280497 304 + 0.210 0.568 2.117
ENSG00000173020 E013 6.6597118 0.0294608809 1.261550e-03 1.789596e-02 11 67280498 67280731 234 + 0.543 0.986 1.802
ENSG00000173020 E014 50.2385881 0.0054612445 8.009136e-03 6.919185e-02 11 67280732 67280783 52 + 1.776 1.637 -0.471
ENSG00000173020 E015 16.1414859 0.0008286991 1.097193e-05 3.710096e-04 11 67280784 67281092 309 + 0.958 1.319 1.296
ENSG00000173020 E016 79.5040620 0.0008271246 7.679046e-03 6.721222e-02 11 67281093 67281184 92 + 1.948 1.852 -0.322
ENSG00000173020 E017 62.5518466 0.0017531560 4.007766e-01 6.841043e-01 11 67281459 67281508 50 + 1.809 1.774 -0.119
ENSG00000173020 E018 48.8297880 0.0002912603 3.340806e-01 6.259886e-01 11 67281509 67281558 50 + 1.708 1.665 -0.145
ENSG00000173020 E019 54.4990828 0.0002618358 1.062658e-01 3.412483e-01 11 67281650 67281683 34 + 1.684 1.752 0.232
ENSG00000173020 E020 64.2508393 0.0002451807 1.315262e-01 3.847314e-01 11 67281684 67281728 45 + 1.760 1.819 0.199
ENSG00000173020 E021 72.5199752 0.0042488340 3.188165e-01 6.114230e-01 11 67281822 67281875 54 + 1.821 1.866 0.150
ENSG00000173020 E022 73.9199481 0.0009122813 5.370734e-01 7.861571e-01 11 67281876 67281952 77 + 1.873 1.850 -0.079
ENSG00000173020 E023 4.7787581 0.0117448065 9.763793e-04 1.475234e-02 11 67281953 67282124 172 + 0.407 0.867 2.032
ENSG00000173020 E024 0.9989652 0.0194709106 4.340221e-01 7.112695e-01 11 67282125 67282150 26 + 0.210 0.334 0.895
ENSG00000173020 E025 2.2362143 0.0457763061 6.992495e-01 8.774498e-01 11 67282151 67282270 120 + 0.457 0.520 0.310
ENSG00000173020 E026 81.9737382 0.0037767274 2.312407e-01 5.197423e-01 11 67282271 67282363 93 + 1.934 1.884 -0.168
ENSG00000173020 E027 35.3206149 0.0031336753 1.186350e-01 3.639086e-01 11 67282364 67282365 2 + 1.597 1.511 -0.296
ENSG00000173020 E028 4.0436648 0.0061172728 3.320933e-05 9.397231e-04 11 67282366 67282434 69 + 0.210 0.831 3.217
ENSG00000173020 E029 55.4654686 0.0068874687 3.387219e-01 6.303462e-01 11 67282435 67282477 43 + 1.767 1.717 -0.172
ENSG00000173020 E030 71.1161829 0.0008688335 8.362879e-01 9.412876e-01 11 67282478 67282542 65 + 1.847 1.839 -0.028
ENSG00000173020 E031 59.5643734 0.0002516575 7.435758e-01 8.986056e-01 11 67282752 67282780 29 + 1.758 1.771 0.044
ENSG00000173020 E032 70.0844746 0.0002228497 6.638598e-01 8.601709e-01 11 67282781 67282818 38 + 1.826 1.841 0.054
ENSG00000173020 E033 64.4338985 0.0002804627 5.799145e-01 8.124558e-01 11 67283128 67283174 47 + 1.813 1.792 -0.073
ENSG00000173020 E034 62.5224125 0.0003206879 2.807903e-01 5.739317e-01 11 67283175 67283228 54 + 1.813 1.771 -0.143
ENSG00000173020 E035 5.4683675 0.0214219307 2.754680e-01 5.690192e-01 11 67283229 67283706 478 + 0.703 0.843 0.563
ENSG00000173020 E036 72.0731658 0.0002001458 7.486095e-02 2.791255e-01 11 67283707 67283773 67 + 1.887 1.823 -0.217
ENSG00000173020 E037 2.6269753 0.0230910138 7.020633e-02 2.680997e-01 11 67283774 67283853 80 + 0.351 0.631 1.397
ENSG00000173020 E038 96.8758071 0.0001758099 1.220725e-01 3.695715e-01 11 67283854 67283949 96 + 2.005 1.956 -0.163
ENSG00000173020 E039 13.2108685 0.0010235885 4.232968e-09 3.215505e-07 11 67283950 67284210 261 + 0.703 1.272 2.133
ENSG00000173020 E040 71.3438434 0.0002193651 7.492597e-01 9.011778e-01 11 67284211 67284270 60 + 1.851 1.839 -0.040
ENSG00000173020 E041 91.7094844 0.0059783998 7.935795e-01 9.212819e-01 11 67284271 67284373 103 + 1.958 1.947 -0.038
ENSG00000173020 E042 2.1226147 0.0311506829 2.229570e-01 5.103956e-01 11 67284374 67284622 249 + 0.351 0.545 1.010
ENSG00000173020 E043 124.2117134 0.0001370283 5.700246e-01 8.068195e-01 11 67284847 67284983 137 + 2.072 2.087 0.052
ENSG00000173020 E044 3.3462012 0.0489779731 6.632414e-01 8.597621e-01 11 67284984 67285074 91 + 0.580 0.650 0.309
ENSG00000173020 E045 46.8761705 0.0025157547 5.634865e-01 8.027839e-01 11 67285075 67285077 3 + 1.646 1.674 0.098
ENSG00000173020 E046 144.0712514 0.0001363691 2.248544e-01 5.123922e-01 11 67285078 67285188 111 + 2.125 2.157 0.105
ENSG00000173020 E047 565.0522755 0.0003036822 6.140916e-04 1.022867e-02 11 67285286 67286055 770 + 2.707 2.753 0.152
ENSG00000173020 E048 188.7860273 0.0001742800 1.099846e-01 3.480759e-01 11 67286056 67286392 337 + 2.239 2.275 0.121
ENSG00000173020 E049 69.5438309 0.0038441822 9.852950e-01 9.989951e-01 11 67286393 67286556 164 + 1.832 1.833 0.004

Help

Please Click HERE to learn more details about the results from DEXseq.