ENSG00000173171

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000316721 ENSG00000173171 No_inf pgKDN_inf MTX1 protein_coding protein_coding 33.6431 31.56924 34.40686 0.5609945 1.442358 0.1241389 2.427200 1.632137 3.6627422 1.2748370 1.2460672 1.1612830 0.07020833 0.051775 0.103475 0.051700 0.72698645 0.03659604 FALSE  
ENST00000424959 ENSG00000173171 No_inf pgKDN_inf MTX1 protein_coding nonsense_mediated_decay 33.6431 31.56924 34.40686 0.5609945 1.442358 0.1241389 3.337319 0.000000 6.1277478 0.0000000 4.4944744 9.2615656 0.09956667 0.000000 0.186350 0.186350 0.52042642 0.03659604 FALSE  
ENST00000481771 ENSG00000173171 No_inf pgKDN_inf MTX1 protein_coding retained_intron 33.6431 31.56924 34.40686 0.5609945 1.442358 0.1241389 1.402162 2.080655 0.2588036 0.2966194 0.1495842 -2.9593305 0.04173333 0.065700 0.007850 -0.057850 0.03659604 0.03659604 FALSE  
ENST00000609421 ENSG00000173171 No_inf pgKDN_inf MTX1 protein_coding protein_coding 33.6431 31.56924 34.40686 0.5609945 1.442358 0.1241389 15.481723 15.727307 13.2721623 1.4556419 5.0769989 -0.2446987 0.45644167 0.496325 0.375825 -0.120500 0.83691150 0.03659604 FALSE  
MSTRG.1964.4 ENSG00000173171 No_inf pgKDN_inf MTX1 protein_coding   33.6431 31.56924 34.40686 0.5609945 1.442358 0.1241389 2.607874 1.662515 4.0703548 1.6625152 0.3228336 1.2866752 0.07826667 0.055275 0.119300 0.064025 0.14633769 0.03659604 FALSE  
MSTRG.1964.5 ENSG00000173171 No_inf pgKDN_inf MTX1 protein_coding   33.6431 31.56924 34.40686 0.5609945 1.442358 0.1241389 3.692385 4.885872 3.2513234 0.5764203 0.5874496 -0.5861083 0.11138333 0.155075 0.094525 -0.060550 0.65140806 0.03659604 TRUE  
MSTRG.1964.8 ENSG00000173171 No_inf pgKDN_inf MTX1 protein_coding   33.6431 31.56924 34.40686 0.5609945 1.442358 0.1241389 2.443578 3.313270 2.6207208 0.4231831 0.4502715 -0.3371454 0.07398333 0.104525 0.076025 -0.028500 0.82947847 0.03659604 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000173171 E001 0.6246350 0.0149655747 0.191075745 0.47044664 1 155208695 155208796 102 + 0.097 0.292 1.938
ENSG00000173171 E002 1.3442100 0.0320751742 0.710235236 0.88288818 1 155208797 155209237 441 + 0.398 0.342 -0.325
ENSG00000173171 E003 2.7751865 0.0053036040 0.044629465 0.20642214 1 155209238 155209246 9 + 0.699 0.428 -1.255
ENSG00000173171 E004 5.6327646 0.0025687585 0.868566459 0.95483711 1 155209247 155209250 4 + 0.829 0.814 -0.062
ENSG00000173171 E005 17.7866789 0.0009722414 0.758533564 0.90516602 1 155209251 155209332 82 + 1.261 1.283 0.077
ENSG00000173171 E006 20.7346330 0.0212419596 0.803661028 0.92708888 1 155210346 155210415 70 + 1.328 1.344 0.057
ENSG00000173171 E007 0.0000000       1 155210416 155210435 20 +      
ENSG00000173171 E008 22.9107531 0.0016057306 0.676036117 0.86582531 1 155210548 155210627 80 + 1.389 1.367 -0.078
ENSG00000173171 E009 0.7537247 0.1548187672 0.145690763 0.40635495 1 155210628 155210734 107 + 0.097 0.342 2.260
ENSG00000173171 E010 1.7492247 0.0086099272 0.035852862 0.18162198 1 155210735 155210847 113 + 0.243 0.561 1.812
ENSG00000173171 E011 1.5947077 0.0534552239 0.873617105 0.95691722 1 155210848 155210894 47 + 0.398 0.428 0.160
ENSG00000173171 E012 4.1809586 0.0035138295 0.584240854 0.81516793 1 155210895 155211391 497 + 0.677 0.744 0.279
ENSG00000173171 E013 0.1272623 0.0126244864 0.567849608   1 155211392 155211546 155 + 0.000 0.093 9.401
ENSG00000173171 E014 9.1692000 0.0018848756 0.007885682 0.06845427 1 155211547 155212126 580 + 0.860 1.105 0.909
ENSG00000173171 E015 20.7745186 0.0016172922 0.251906936 0.54318351 1 155212127 155212219 93 + 1.371 1.305 -0.232
ENSG00000173171 E016 2.3436211 0.0072265576 0.558516229 0.80014897 1 155212220 155212384 165 + 0.477 0.561 0.397
ENSG00000173171 E017 16.8722022 0.0008672950 0.311439345 0.60460508 1 155212385 155212454 70 + 1.285 1.219 -0.230
ENSG00000173171 E018 8.0711318 0.0018590722 0.487139528 0.75076759 1 155212455 155212567 113 + 0.989 0.926 -0.237
ENSG00000173171 E019 0.8462153 0.0173433205 0.233140290 0.52188048 1 155212568 155212693 126 + 0.352 0.170 -1.384
ENSG00000173171 E020 0.3731018 0.0168441696 0.615043053   1 155212694 155212770 77 + 0.097 0.170 0.938
ENSG00000173171 E021 0.0000000       1 155213237 155213391 155 +      
ENSG00000173171 E022 0.0000000       1 155213392 155213483 92 +      
ENSG00000173171 E023 0.0000000       1 155213484 155213824 341 +      

Help

Please Click HERE to learn more details about the results from DEXseq.