ENSG00000173442

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000309295 ENSG00000173442 No_inf pgKDN_inf EHBP1L1 protein_coding protein_coding 86.55265 78.94115 85.0055 6.673975 5.473516 0.1067655 29.432686 16.430617 37.875144 0.8060575 1.2339108 1.2043678 0.33912500 0.212900 0.44890 0.236000 0.0002638515 0.0002638515 FALSE TRUE
ENST00000526990 ENSG00000173442 No_inf pgKDN_inf EHBP1L1 protein_coding retained_intron 86.55265 78.94115 85.0055 6.673975 5.473516 0.1067655 8.274489 11.927043 4.453025 1.0103620 0.5399303 -1.4193518 0.09831667 0.152800 0.05390 -0.098900 0.0264682626 0.0002638515 FALSE TRUE
ENST00000533364 ENSG00000173442 No_inf pgKDN_inf EHBP1L1 protein_coding retained_intron 86.55265 78.94115 85.0055 6.673975 5.473516 0.1067655 14.212486 17.104903 10.854653 1.0307963 0.7625935 -0.6556110 0.16725833 0.219825 0.12910 -0.090725 0.2184909139 0.0002638515 FALSE TRUE
MSTRG.4955.10 ENSG00000173442 No_inf pgKDN_inf EHBP1L1 protein_coding   86.55265 78.94115 85.0055 6.673975 5.473516 0.1067655 13.432356 8.320456 12.415506 0.6796705 2.1659455 0.5768372 0.15406667 0.108025 0.14945 0.041425 0.8181275899 0.0002638515 FALSE TRUE
MSTRG.4955.4 ENSG00000173442 No_inf pgKDN_inf EHBP1L1 protein_coding   86.55265 78.94115 85.0055 6.673975 5.473516 0.1067655 11.221921 16.343916 6.909450 1.0435888 0.3786536 -1.2409068 0.13367500 0.209450 0.08290 -0.126550 0.0087322396 0.0002638515 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000173442 E001 0.0000000       11 65576000 65576037 38 +      
ENSG00000173442 E002 1.1127593 1.097330e-02 2.249807e-01 5.126150e-01 11 65576038 65576045 8 + 0.225 0.413 1.221
ENSG00000173442 E003 1.7289637 8.636547e-03 1.836679e-01 4.605295e-01 11 65576046 65576052 7 + 0.329 0.529 1.069
ENSG00000173442 E004 2.5702321 1.796186e-02 5.937855e-01 8.211555e-01 11 65576053 65576061 9 + 0.514 0.592 0.359
ENSG00000173442 E005 34.2818835 7.956072e-03 1.608545e-01 4.288447e-01 11 65576062 65576406 345 + 1.587 1.500 -0.295
ENSG00000173442 E006 3.6079392 2.404423e-02 8.790661e-03 7.373498e-02 11 65578201 65578278 78 + 0.449 0.816 1.614
ENSG00000173442 E007 15.6397870 1.014899e-03 9.079727e-01 9.706986e-01 11 65579078 65579081 4 + 1.215 1.227 0.041
ENSG00000173442 E008 27.1548222 5.985567e-04 2.109791e-01 4.958147e-01 11 65579082 65579135 54 + 1.481 1.412 -0.235
ENSG00000173442 E009 36.3512222 1.901914e-03 4.068379e-02 1.957170e-01 11 65579341 65579436 96 + 1.619 1.515 -0.356
ENSG00000173442 E010 28.4988710 5.843665e-03 3.289747e-01 6.214465e-01 11 65579936 65579989 54 + 1.497 1.438 -0.201
ENSG00000173442 E011 67.0618049 2.231045e-03 5.261034e-02 2.279472e-01 11 65580081 65580259 179 + 1.868 1.791 -0.260
ENSG00000173442 E012 65.1258174 3.229459e-04 3.017071e-02 1.633598e-01 11 65580337 65580479 143 + 1.856 1.778 -0.263
ENSG00000173442 E013 0.2448930 1.644404e-02 9.098430e-01   11 65580928 65580963 36 + 0.089 0.102 0.221
ENSG00000173442 E014 35.4176402 3.966649e-04 1.026653e-01 3.349880e-01 11 65581058 65581126 69 + 1.597 1.518 -0.269
ENSG00000173442 E015 38.8917440 3.647963e-04 3.767531e-01 6.639407e-01 11 65581211 65581251 41 + 1.619 1.580 -0.133
ENSG00000173442 E016 42.6758873 3.511361e-04 4.377067e-01 7.139440e-01 11 65581252 65581326 75 + 1.655 1.623 -0.110
ENSG00000173442 E017 20.6900812 1.424249e-02 3.311386e-01 6.234596e-01 11 65581327 65581373 47 + 1.370 1.296 -0.258
ENSG00000173442 E018 0.2438580 1.637937e-02 9.097250e-01   11 65581524 65581538 15 + 0.089 0.102 0.221
ENSG00000173442 E019 57.2854386 2.635168e-04 1.455996e-02 1.029553e-01 11 65581539 65581790 252 + 1.808 1.714 -0.318
ENSG00000173442 E020 34.9119488 4.017809e-04 7.529174e-02 2.801145e-01 11 65581791 65581870 80 + 1.594 1.508 -0.297
ENSG00000173442 E021 29.2047794 4.650782e-04 1.462156e-01 4.071659e-01 11 65581871 65581898 28 + 1.515 1.438 -0.264
ENSG00000173442 E022 40.5355386 3.657407e-04 7.484697e-01 9.006886e-01 11 65581899 65581965 67 + 1.624 1.612 -0.040
ENSG00000173442 E023 25.6835772 1.900946e-03 5.389367e-01 7.874678e-01 11 65581966 65582016 51 + 1.406 1.446 0.139
ENSG00000173442 E024 327.0679765 7.072875e-05 4.318850e-03 4.475174e-02 11 65582017 65583591 1575 + 2.535 2.494 -0.139
ENSG00000173442 E025 42.1923491 3.432274e-04 4.262849e-01 7.049478e-01 11 65583592 65583765 174 + 1.651 1.617 -0.114
ENSG00000173442 E026 28.5320432 4.839014e-04 1.700700e-16 3.347648e-14 11 65583766 65584240 475 + 1.171 1.657 1.683
ENSG00000173442 E027 42.2395191 3.463791e-04 2.347776e-01 5.239365e-01 11 65584241 65584294 54 + 1.607 1.665 0.196
ENSG00000173442 E028 61.7735907 2.407554e-04 6.823471e-01 8.685848e-01 11 65584295 65584398 104 + 1.803 1.791 -0.042
ENSG00000173442 E029 0.3813786 3.112791e-02 7.987256e-02   11 65584399 65584485 87 + 0.000 0.254 10.299
ENSG00000173442 E030 43.6782014 3.248139e-04 5.109959e-02 2.238061e-01 11 65584486 65584534 49 + 1.689 1.603 -0.290
ENSG00000173442 E031 0.9981451 1.209198e-02 1.031313e-01 3.356233e-01 11 65584535 65584692 158 + 0.162 0.413 1.806
ENSG00000173442 E032 156.2472615 1.302499e-04 1.089950e-05 3.687915e-04 11 65584959 65585591 633 + 2.242 2.140 -0.340
ENSG00000173442 E033 42.8887095 3.401439e-04 2.775225e-01 5.707699e-01 11 65589751 65589820 70 + 1.664 1.617 -0.158
ENSG00000173442 E034 37.1601868 4.791894e-03 2.181670e-01 5.046460e-01 11 65589936 65589991 56 + 1.612 1.545 -0.227
ENSG00000173442 E035 69.1553033 1.614050e-03 2.812392e-01 5.745274e-01 11 65590087 65590210 124 + 1.823 1.869 0.155
ENSG00000173442 E036 82.1298411 2.536926e-03 6.772315e-01 8.661767e-01 11 65590493 65590592 100 + 1.910 1.930 0.067
ENSG00000173442 E037 58.1112709 3.924455e-03 1.495515e-25 6.351113e-23 11 65590593 65591194 602 + 1.447 1.967 1.765
ENSG00000173442 E038 27.7453118 4.929437e-04 1.118208e-21 3.526869e-19 11 65591195 65591388 194 + 1.083 1.670 2.041
ENSG00000173442 E039 36.0413114 1.840898e-03 1.056483e-21 3.371617e-19 11 65591389 65591635 247 + 1.233 1.768 1.840
ENSG00000173442 E040 19.8236081 6.839824e-04 1.172001e-06 5.356837e-05 11 65591636 65591799 164 + 1.129 1.459 1.154
ENSG00000173442 E041 34.3328822 1.247823e-02 2.811403e-01 5.744055e-01 11 65591800 65591807 8 + 1.579 1.511 -0.233
ENSG00000173442 E042 37.3381349 4.022226e-04 6.590395e-01 8.576110e-01 11 65591808 65591821 14 + 1.592 1.574 -0.062
ENSG00000173442 E043 53.1952141 3.341999e-04 5.571622e-01 7.992478e-01 11 65591822 65591873 52 + 1.744 1.723 -0.071
ENSG00000173442 E044 0.0000000       11 65591874 65591959 86 +      
ENSG00000173442 E045 0.9998465 1.196390e-02 1.032034e-01 3.357767e-01 11 65591960 65591975 16 + 0.162 0.413 1.806
ENSG00000173442 E046 52.4201334 3.183708e-04 8.385256e-01 9.421068e-01 11 65591976 65592008 33 + 1.722 1.733 0.040
ENSG00000173442 E047 32.5070308 4.224321e-04 8.371507e-01 9.416635e-01 11 65592009 65592013 5 + 1.518 1.532 0.048
ENSG00000173442 E048 53.2164058 6.926475e-04 1.432874e-01 4.031121e-01 11 65592014 65592090 77 + 1.761 1.703 -0.197
ENSG00000173442 E049 116.3128799 3.463076e-03 6.926220e-01 8.741897e-01 11 65592203 65592688 486 + 2.074 2.063 -0.037

Help

Please Click HERE to learn more details about the results from DEXseq.