ENSG00000173473

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000485833 ENSG00000173473 No_inf pgKDN_inf SMARCC1 protein_coding protein_coding_CDS_not_defined 35.18864 30.36779 40.58962 2.604176 1.483046 0.4184494 2.616608 3.247427 2.476368 2.1961656 1.4486401 -0.3896927 0.06763333 0.091775 0.057525 -0.034250 0.99287902 0.02713196 FALSE  
MSTRG.20096.2 ENSG00000173473 No_inf pgKDN_inf SMARCC1 protein_coding   35.18864 30.36779 40.58962 2.604176 1.483046 0.4184494 14.259620 9.577705 18.950922 0.5201247 1.4021244 0.9837716 0.40308333 0.325025 0.468650 0.143625 0.41638000 0.02713196 FALSE  
MSTRG.20096.3 ENSG00000173473 No_inf pgKDN_inf SMARCC1 protein_coding   35.18864 30.36779 40.58962 2.604176 1.483046 0.4184494 15.013408 13.870471 16.931862 1.4057442 0.7984947 0.2875360 0.43248333 0.464000 0.419050 -0.044950 0.87483329 0.02713196 TRUE  
MSTRG.20096.4 ENSG00000173473 No_inf pgKDN_inf SMARCC1 protein_coding   35.18864 30.36779 40.58962 2.604176 1.483046 0.4184494 1.535841 1.969806 0.000000 0.7132935 0.0000000 -7.6292155 0.04700000 0.063500 0.000000 -0.063500 0.02713196 0.02713196 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000173473 E001 1.9652303 0.0323595754 3.169904e-01 6.097236e-01 3 47585269 47585755 487 - 0.396 0.549 0.770
ENSG00000173473 E002 0.4884040 0.0158585742 7.778232e-01   3 47585756 47585786 31 - 0.154 0.194 0.407
ENSG00000173473 E003 0.4982540 0.0152640081 2.013095e-01   3 47585787 47585797 11 - 0.084 0.266 1.992
ENSG00000173473 E004 346.7416521 0.0001498908 3.904302e-09 2.991117e-07 3 47585798 47587589 1792 - 2.500 2.582 0.273
ENSG00000173473 E005 123.3866452 0.0009689700 2.951380e-03 3.412213e-02 3 47587590 47588306 717 - 2.053 2.136 0.278
ENSG00000173473 E006 33.8398543 0.0105912345 9.913997e-01 1.000000e+00 3 47590661 47590805 145 - 1.541 1.538 -0.011
ENSG00000173473 E007 16.8059450 0.0068490687 9.770577e-01 9.964004e-01 3 47590806 47590837 32 - 1.250 1.246 -0.014
ENSG00000173473 E008 46.5800438 0.0003174236 5.317841e-01 7.823153e-01 3 47610066 47610327 262 - 1.663 1.689 0.088
ENSG00000173473 E009 0.0000000       3 47610525 47610798 274 -      
ENSG00000173473 E010 32.7154823 0.0004267663 4.226880e-01 7.019496e-01 3 47622207 47622341 135 - 1.544 1.501 -0.147
ENSG00000173473 E011 48.1120568 0.0079497511 2.139025e-01 4.991821e-01 3 47635190 47635341 152 - 1.720 1.647 -0.245
ENSG00000173473 E012 19.4633648 0.0065090087 5.968457e-01 8.229447e-01 3 47635342 47635344 3 - 1.326 1.286 -0.141
ENSG00000173473 E013 37.6423017 0.0011773852 9.419433e-01 9.836326e-01 3 47636022 47636136 115 - 1.587 1.582 -0.016
ENSG00000173473 E014 15.2610981 0.0009142717 5.504245e-01 7.948458e-01 3 47638725 47638780 56 - 1.189 1.232 0.152
ENSG00000173473 E015 0.8794446 0.0235284499 2.152852e-02 1.329272e-01 3 47658558 47658771 214 - 0.084 0.430 2.992
ENSG00000173473 E016 31.4795377 0.0004356090 3.649358e-01 6.533592e-01 3 47661294 47661455 162 - 1.531 1.482 -0.169
ENSG00000173473 E017 40.7531396 0.0039448926 7.118808e-02 2.703556e-01 3 47662334 47662592 259 - 1.659 1.562 -0.330
ENSG00000173473 E018 0.0000000       3 47670350 47670657 308 -      
ENSG00000173473 E019 15.0390552 0.0141200236 2.657128e-01 5.590823e-01 3 47670658 47670717 60 - 1.245 1.145 -0.354
ENSG00000173473 E020 19.2543081 0.0109390409 8.608734e-01 9.518444e-01 3 47675475 47675588 114 - 1.299 1.311 0.040
ENSG00000173473 E021 25.6377161 0.0005343272 2.906572e-01 5.841763e-01 3 47676629 47676782 154 - 1.450 1.387 -0.218
ENSG00000173473 E022 0.2458395 0.0164232931 8.251310e-01   3 47678196 47678197 2 - 0.084 0.108 0.407
ENSG00000173473 E023 25.5645501 0.0280356848 1.348044e-01 3.903435e-01 3 47678198 47678311 114 - 1.476 1.345 -0.452
ENSG00000173473 E024 0.0000000       3 47678312 47678365 54 -      
ENSG00000173473 E025 1.0947585 0.0144406470 9.279125e-01 9.786230e-01 3 47680223 47680436 214 - 0.314 0.328 0.085
ENSG00000173473 E026 17.9188196 0.0007602873 5.429415e-02 2.320365e-01 3 47680437 47680508 72 - 1.331 1.195 -0.478
ENSG00000173473 E027 23.9383355 0.0012949831 6.729471e-03 6.140201e-02 3 47686049 47686170 122 - 1.463 1.292 -0.593
ENSG00000173473 E028 14.6598639 0.0013915106 1.469219e-01 4.080021e-01 3 47689387 47689424 38 - 1.240 1.127 -0.400
ENSG00000173473 E029 14.1951584 0.0010495849 2.456987e-01 5.362815e-01 3 47693241 47693300 60 - 1.218 1.127 -0.323
ENSG00000173473 E030 24.1198512 0.0010482053 9.994545e-01 1.000000e+00 3 47701278 47701402 125 - 1.398 1.397 -0.004
ENSG00000173473 E031 0.0000000       3 47701403 47701654 252 -      
ENSG00000173473 E032 25.6139256 0.0005434111 1.814501e-01 4.574548e-01 3 47706409 47706530 122 - 1.457 1.377 -0.276
ENSG00000173473 E033 21.3641215 0.0006483197 1.921012e-01 4.719100e-01 3 47710683 47710808 126 - 1.383 1.298 -0.295
ENSG00000173473 E034 12.6396006 0.0012622651 4.724329e-01 7.397142e-01 3 47714415 47714490 76 - 1.158 1.099 -0.213
ENSG00000173473 E035 0.1187032 0.0118766856 7.143068e-01   3 47718022 47718063 42 - 0.084 0.000 -9.809
ENSG00000173473 E036 12.6030508 0.0010967363 1.291579e-01 3.813017e-01 3 47720666 47720735 70 - 1.183 1.058 -0.450
ENSG00000173473 E037 7.3743521 0.0039304732 6.494809e-02 2.567363e-01 3 47729025 47729036 12 - 0.997 0.803 -0.737
ENSG00000173473 E038 10.9210211 0.0013566307 2.305145e-01 5.190056e-01 3 47729037 47729094 58 - 1.118 1.013 -0.382
ENSG00000173473 E039 15.8292993 0.0008681571 7.492839e-01 9.011778e-01 3 47736034 47736126 93 - 1.234 1.210 -0.086
ENSG00000173473 E040 14.4659001 0.0023325052 4.596624e-01 7.313107e-01 3 47738029 47738110 82 - 1.212 1.154 -0.208
ENSG00000173473 E041 13.3316618 0.0011308183 1.128086e-01 3.533639e-01 3 47745908 47745993 86 - 1.207 1.079 -0.457
ENSG00000173473 E042 0.2441377 0.0164259291 8.251296e-01   3 47746325 47746405 81 - 0.084 0.108 0.407
ENSG00000173473 E043 13.8136129 0.0011525352 1.331394e-01 3.874989e-01 3 47772817 47772936 120 - 1.218 1.099 -0.425
ENSG00000173473 E044 13.2004939 0.0011107097 1.314965e-01 3.846685e-01 3 47781603 47781893 291 - 1.201 1.079 -0.437
ENSG00000173473 E045 0.1187032 0.0118766856 7.143068e-01   3 47782022 47782106 85 - 0.084 0.000 -9.809

Help

Please Click HERE to learn more details about the results from DEXseq.