ENSG00000173692

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000308696 ENSG00000173692 No_inf pgKDN_inf PSMD1 protein_coding protein_coding 43.68115 36.11312 45.99818 2.714734 1.79822 0.3489677 30.695109 17.208546 38.9564269 3.0704224 0.4357427 1.178268 0.69835833 0.500325 0.851150 0.350825 0.015918901 0.005542974 FALSE TRUE
ENST00000431051 ENSG00000173692 No_inf pgKDN_inf PSMD1 protein_coding nonsense_mediated_decay 43.68115 36.11312 45.99818 2.714734 1.79822 0.3489677 1.234974 3.704923 0.0000000 3.7049230 0.0000000 -8.537188 0.02796667 0.083900 0.000000 -0.083900 0.836010587 0.005542974 FALSE TRUE
ENST00000447633 ENSG00000173692 No_inf pgKDN_inf PSMD1 protein_coding retained_intron 43.68115 36.11312 45.99818 2.714734 1.79822 0.3489677 1.503213 2.888989 0.9925372 1.9741570 0.9925372 -1.531894 0.03497500 0.071125 0.019850 -0.051275 0.787716002 0.005542974 FALSE TRUE
ENST00000491229 ENSG00000173692 No_inf pgKDN_inf PSMD1 protein_coding retained_intron 43.68115 36.11312 45.99818 2.714734 1.79822 0.3489677 2.090098 4.469135 0.5424324 0.8952671 0.1889012 -3.019350 0.05558333 0.127475 0.011825 -0.115650 0.005542974 0.005542974   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000173692 E001 0.1170040 0.0116972651 7.489787e-01   2 231056845 231056848 4 + 0.082 0.000 -9.405
ENSG00000173692 E002 0.1170040 0.0116972651 7.489787e-01   2 231056849 231056863 15 + 0.082 0.000 -11.920
ENSG00000173692 E003 0.1170040 0.0116972651 7.489787e-01   2 231056864 231056866 3 + 0.082 0.000 -11.920
ENSG00000173692 E004 0.4719759 0.0151265626 9.275537e-02   2 231056867 231056874 8 + 0.262 0.000 -13.803
ENSG00000173692 E005 0.4719759 0.0151265626 9.275537e-02   2 231056875 231056878 4 + 0.262 0.000 -13.803
ENSG00000173692 E006 2.1677911 0.0071547672 2.218641e-01 5.091148e-01 2 231056879 231056893 15 + 0.568 0.388 -0.899
ENSG00000173692 E007 14.8481197 0.0009569848 7.350789e-03 6.524974e-02 2 231056894 231057041 148 + 1.275 1.068 -0.737
ENSG00000173692 E008 0.3642603 0.1760876249 8.372495e-01   2 231057173 231057540 368 + 0.151 0.110 -0.521
ENSG00000173692 E009 11.2900088 0.0021633147 5.215372e-04 9.023163e-03 2 231061267 231061310 44 + 1.196 0.884 -1.146
ENSG00000173692 E010 15.2011668 0.0012925444 1.265283e-02 9.357162e-02 2 231062248 231062321 74 + 1.279 1.089 -0.678
ENSG00000173692 E011 26.3330658 0.0006374949 1.987377e-03 2.545524e-02 2 231062506 231062675 170 + 1.504 1.321 -0.631
ENSG00000173692 E012 0.0000000       2 231062676 231062693 18 +      
ENSG00000173692 E013 30.5137569 0.0004455654 1.689194e-02 1.133807e-01 2 231066906 231067111 206 + 1.547 1.417 -0.444
ENSG00000173692 E014 20.8478273 0.0006589117 1.207031e-01 3.675269e-01 2 231070025 231070168 144 + 1.377 1.277 -0.347
ENSG00000173692 E015 24.0896401 0.0009318882 3.986276e-02 1.935330e-01 2 231072189 231072332 144 + 1.446 1.321 -0.434
ENSG00000173692 E016 19.4200609 0.0049096595 3.268341e-03 3.685443e-02 2 231072333 231072415 83 + 1.388 1.172 -0.755
ENSG00000173692 E017 18.0821996 0.0011225584 2.928591e-01 5.864358e-01 2 231075511 231075571 61 + 1.307 1.235 -0.252
ENSG00000173692 E018 28.0430092 0.0082551851 3.906553e-01 6.761266e-01 2 231077034 231077162 129 + 1.483 1.427 -0.194
ENSG00000173692 E019 22.3645955 0.0006389237 8.560989e-03 7.235988e-02 2 231078659 231078747 89 + 1.430 1.263 -0.579
ENSG00000173692 E020 0.0000000       2 231078917 231079535 619 +      
ENSG00000173692 E021 21.0986696 0.0006574595 1.292200e-01 3.813807e-01 2 231079536 231079614 79 + 1.380 1.284 -0.337
ENSG00000173692 E022 0.1272623 0.0123924916 3.840395e-01   2 231079615 231079770 156 + 0.000 0.110 12.030
ENSG00000173692 E023 31.3874827 0.0004460834 7.054398e-01 8.803552e-01 2 231080141 231080314 174 + 1.515 1.496 -0.063
ENSG00000173692 E024 26.2599415 0.0081434575 6.053972e-01 8.280316e-01 2 231082883 231082994 112 + 1.446 1.413 -0.116
ENSG00000173692 E025 0.0000000       2 231083564 231083566 3 +      
ENSG00000173692 E026 49.2332333 0.0003094701 6.159860e-01 8.334366e-01 2 231083567 231083763 197 + 1.687 1.710 0.077
ENSG00000173692 E027 28.5558412 0.0005110127 2.868182e-01 5.802590e-01 2 231085019 231085079 61 + 1.440 1.500 0.208
ENSG00000173692 E028 22.5380624 0.0022614914 3.204706e-02 1.693207e-01 2 231085080 231085114 35 + 1.303 1.441 0.480
ENSG00000173692 E029 26.7639549 0.0006530482 1.233373e-01 3.717564e-01 2 231087117 231087181 65 + 1.399 1.488 0.308
ENSG00000173692 E030 0.0000000       2 231108564 231109122 559 +      
ENSG00000173692 E031 2.1144582 0.0069317022 1.819058e-02 1.191286e-01 2 231138115 231138735 621 + 0.309 0.650 1.743
ENSG00000173692 E032 38.9956611 0.0011501021 6.870064e-02 2.646832e-01 2 231138736 231138850 115 + 1.557 1.647 0.308
ENSG00000173692 E033 0.8684310 0.2576085903 2.065613e-01 4.902072e-01 2 231138851 231139070 220 + 0.150 0.388 1.803
ENSG00000173692 E034 37.0765928 0.0009667191 5.104438e-01 7.680052e-01 2 231146240 231146356 117 + 1.562 1.596 0.117
ENSG00000173692 E035 3.7905253 0.0036182013 2.512950e-09 1.993139e-07 2 231146357 231149450 3094 + 0.151 0.959 4.287
ENSG00000173692 E036 0.1187032 0.0118074470 7.489520e-01   2 231151857 231151928 72 + 0.082 0.000 -11.920
ENSG00000173692 E037 1.7492903 0.0170847122 6.355947e-03 5.888280e-02 2 231151929 231152716 788 + 0.210 0.621 2.354
ENSG00000173692 E038 0.8610324 0.0121594156 4.208825e-01 7.000349e-01 2 231152717 231152811 95 + 0.210 0.334 0.895
ENSG00000173692 E039 2.1045477 0.0115902054 6.425192e-02 2.552523e-01 2 231152812 231153468 657 + 0.351 0.621 1.354
ENSG00000173692 E040 0.6258335 0.0149703791 8.543300e-02 3.024446e-01 2 231153469 231153563 95 + 0.082 0.334 2.480
ENSG00000173692 E041 35.3575264 0.0004079701 2.916871e-01 5.851242e-01 2 231153564 231153666 103 + 1.579 1.527 -0.176
ENSG00000173692 E042 0.2459655 0.0162469858 7.981195e-01   2 231153667 231153927 261 + 0.082 0.110 0.480
ENSG00000173692 E043 47.6663935 0.0003598772 5.988945e-01 8.240431e-01 2 231161340 231161509 170 + 1.693 1.672 -0.071
ENSG00000173692 E044 3.7639332 0.0089792885 5.410514e-06 2.015267e-04 2 231161510 231163084 1575 + 0.309 0.915 2.802
ENSG00000173692 E045 2.4833755 0.0063184395 1.223976e-02 9.156460e-02 2 231163093 231163587 495 + 0.351 0.703 1.702
ENSG00000173692 E046 0.6177427 0.2795406293 5.827656e-01 8.141570e-01 2 231163588 231163634 47 + 0.151 0.271 1.065
ENSG00000173692 E047 36.7671343 0.0003963508 9.431076e-01 9.842109e-01 2 231163635 231163727 93 + 1.571 1.576 0.017
ENSG00000173692 E048 0.1265070 0.0122634501 3.841437e-01   2 231164959 231165199 241 + 0.000 0.110 12.031
ENSG00000173692 E049 50.6209928 0.0021227123 8.447266e-01 9.446688e-01 2 231165200 231165286 87 + 1.712 1.705 -0.025
ENSG00000173692 E050 0.0000000       2 231165287 231165287 1 +      
ENSG00000173692 E051 88.1586406 0.0001972643 1.760619e-01 4.502049e-01 2 231165871 231166017 147 + 1.927 1.971 0.147
ENSG00000173692 E052 1.7116829 0.0542753186 5.642141e-01 8.034409e-01 2 231166018 231166380 363 + 0.389 0.481 0.481
ENSG00000173692 E053 1.2299196 0.0983572042 3.009091e-01 5.938900e-01 2 231166381 231166491 111 + 0.262 0.437 1.066
ENSG00000173692 E054 3.9788735 0.0063116652 7.820406e-04 1.240182e-02 2 231166492 231167229 738 + 0.457 0.884 1.833
ENSG00000173692 E055 4.6603689 0.0030480102 2.252311e-09 1.796984e-07 2 231170402 231170565 164 + 0.262 1.023 3.524
ENSG00000173692 E056 28.4118386 0.0007136174 1.286200e-02 9.460356e-02 2 231170566 231170578 13 + 1.399 1.538 0.480
ENSG00000173692 E057 72.1783565 0.0002209540 2.253567e-01 5.131464e-01 2 231170579 231170721 143 + 1.841 1.885 0.147
ENSG00000173692 E058 5.1479344 0.0775882142 2.685062e-01 5.620218e-01 2 231170722 231171521 800 + 0.711 0.867 0.618
ENSG00000173692 E059 52.2006672 0.0003289615 9.574782e-01 9.898200e-01 2 231172535 231173116 582 + 1.723 1.722 -0.002

Help

Please Click HERE to learn more details about the results from DEXseq.