ENSG00000173992

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000525435 ENSG00000173992 No_inf pgKDN_inf CCS protein_coding retained_intron 21.20124 28.55617 17.33315 1.838801 0.7704985 -0.7199421 1.061109 0.9975369 1.7657479 0.9975369 0.6562511 0.8175942 0.05139167 0.029300 0.102300 0.073000 0.3886392195 0.0004559865 TRUE FALSE
ENST00000526066 ENSG00000173992 No_inf pgKDN_inf CCS protein_coding retained_intron 21.20124 28.55617 17.33315 1.838801 0.7704985 -0.7199421 2.017258 3.9634190 0.6180878 1.1909859 0.4246461 -2.6613427 0.08591667 0.133900 0.038575 -0.095325 0.3384402905 0.0004559865 FALSE FALSE
ENST00000530384 ENSG00000173992 No_inf pgKDN_inf CCS protein_coding retained_intron 21.20124 28.55617 17.33315 1.838801 0.7704985 -0.7199421 3.959996 6.9531786 1.6094097 1.3404083 0.9282058 -2.1042780 0.17657500 0.252800 0.091725 -0.161075 0.4037740300 0.0004559865 TRUE FALSE
ENST00000530961 ENSG00000173992 No_inf pgKDN_inf CCS protein_coding nonsense_mediated_decay 21.20124 28.55617 17.33315 1.838801 0.7704985 -0.7199421 1.162969 2.8149128 0.5393637 1.0262677 0.5393637 -2.3623727 0.04755833 0.105000 0.029725 -0.075275 0.4947729567 0.0004559865 TRUE TRUE
ENST00000533244 ENSG00000173992 No_inf pgKDN_inf CCS protein_coding protein_coding 21.20124 28.55617 17.33315 1.838801 0.7704985 -0.7199421 9.521721 7.1302470 12.1123995 1.8775545 1.2412070 0.7636294 0.48773333 0.241250 0.698925 0.457675 0.0004559865 0.0004559865 FALSE TRUE
ENST00000534763 ENSG00000173992 No_inf pgKDN_inf CCS protein_coding protein_coding 21.20124 28.55617 17.33315 1.838801 0.7704985 -0.7199421 3.356325 6.6968775 0.6881374 0.3201342 0.5398939 -3.2640584 0.14442500 0.237775 0.038800 -0.198975 0.0419280610 0.0004559865 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000173992 E001 0.7512093 0.0328379266 3.794569e-01 0.6662160210 11 66593153 66593184 32 + 0.129 0.272 1.336
ENSG00000173992 E002 0.7512093 0.0328379266 3.794569e-01 0.6662160210 11 66593185 66593189 5 + 0.129 0.272 1.336
ENSG00000173992 E003 1.3866396 0.0093392881 6.034272e-02 0.2465128819 11 66593190 66593200 11 + 0.129 0.438 2.336
ENSG00000173992 E004 1.3866396 0.0093392881 6.034272e-02 0.2465128819 11 66593201 66593203 3 + 0.129 0.438 2.336
ENSG00000173992 E005 3.9614035 0.0039178450 9.031527e-01 0.9688646579 11 66593204 66593232 29 + 0.680 0.668 -0.052
ENSG00000173992 E006 4.0902390 0.0036707180 9.979992e-01 1.0000000000 11 66593233 66593240 8 + 0.680 0.684 0.015
ENSG00000173992 E007 6.5635123 0.0026161958 6.996315e-01 0.8775975819 11 66593241 66593300 60 + 0.878 0.840 -0.146
ENSG00000173992 E008 0.0000000       11 66593610 66593641 32 +      
ENSG00000173992 E009 7.0368578 0.0056216344 2.762668e-01 0.5697744310 11 66593642 66593714 73 + 0.950 0.840 -0.421
ENSG00000173992 E010 15.0144272 0.0012053777 1.680782e-02 0.1130695576 11 66599116 66599253 138 + 1.284 1.114 -0.604
ENSG00000173992 E011 9.1578856 0.0015975357 9.629916e-04 0.0145811306 11 66599254 66599458 205 + 0.710 1.065 1.361
ENSG00000173992 E012 22.9536081 0.0006657346 7.754840e-01 0.9138019220 11 66599459 66599636 178 + 1.336 1.357 0.074
ENSG00000173992 E013 3.5382046 0.0050642562 9.204143e-04 0.0140947262 11 66599637 66599803 167 + 0.228 0.742 2.715
ENSG00000173992 E014 8.0699238 0.0020497982 5.173208e-06 0.0001936237 11 66600034 66600434 401 + 0.487 1.045 2.288
ENSG00000173992 E015 1.9946558 0.0076676419 4.717331e-01 0.7390577857 11 66600435 66600488 54 + 0.376 0.490 0.600
ENSG00000173992 E016 13.7838426 0.0010989962 5.274892e-01 0.7794411342 11 66600489 66600549 61 + 1.104 1.158 0.194
ENSG00000173992 E017 3.4920295 0.0080419461 3.407730e-01 0.6323722321 11 66605154 66605338 185 + 0.533 0.668 0.600
ENSG00000173992 E018 15.8597224 0.0008950977 9.526495e-01 0.9882517886 11 66605339 66605416 78 + 1.199 1.198 -0.002
ENSG00000173992 E019 22.9584274 0.0006458982 1.034491e-01 0.3362034037 11 66605489 66605592 104 + 1.412 1.319 -0.322
ENSG00000173992 E020 28.9282075 0.0007793086 8.864335e-04 0.0136831442 11 66605702 66606019 318 + 1.554 1.386 -0.577

Help

Please Click HERE to learn more details about the results from DEXseq.