ENSG00000174177

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000312060 ENSG00000174177 No_inf pgKDN_inf CTU2 protein_coding protein_coding 18.58954 14.95207 20.0077 1.664925 1.311906 0.4199662 3.5864625 1.8981178 1.0680222 1.1131260 1.0680222 -0.8237634 0.19735833 0.141925 0.064625 -0.077300 0.799496310 0.001217105 FALSE TRUE
ENST00000453996 ENSG00000174177 No_inf pgKDN_inf CTU2 protein_coding protein_coding 18.58954 14.95207 20.0077 1.664925 1.311906 0.4199662 9.3691727 5.9799556 14.1667569 2.4568566 1.4986679 1.2429103 0.48450833 0.373975 0.704500 0.330525 0.442846107 0.001217105 FALSE TRUE
ENST00000562011 ENSG00000174177 No_inf pgKDN_inf CTU2 protein_coding retained_intron 18.58954 14.95207 20.0077 1.664925 1.311906 0.4199662 1.4573056 1.8913689 0.9789436 0.6418249 0.9789436 -0.9430783 0.07786667 0.125800 0.043525 -0.082275 0.424986259 0.001217105   FALSE
ENST00000566637 ENSG00000174177 No_inf pgKDN_inf CTU2 protein_coding retained_intron 18.58954 14.95207 20.0077 1.664925 1.311906 0.4199662 0.9920350 1.6359837 0.0000000 0.3967485 0.0000000 -7.3628063 0.06349167 0.122525 0.000000 -0.122525 0.001217105 0.001217105 TRUE TRUE
ENST00000567316 ENSG00000174177 No_inf pgKDN_inf CTU2 protein_coding protein_coding 18.58954 14.95207 20.0077 1.664925 1.311906 0.4199662 0.8720944 0.2940797 1.8457633 0.2940797 0.9950890 2.6094912 0.04515833 0.022150 0.092475 0.070325 0.526504570 0.001217105 FALSE FALSE
ENST00000567949 ENSG00000174177 No_inf pgKDN_inf CTU2 protein_coding protein_coding 18.58954 14.95207 20.0077 1.664925 1.311906 0.4199662 0.9643806 1.0938890 0.8419957 0.2673708 0.4507122 -0.3736771 0.05768333 0.081750 0.042375 -0.039375 0.811685779 0.001217105 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174177 E001 0.1268540 0.0126113643 0.4092589272   16 88706483 88706502 20 + 0.000 0.108 9.976
ENSG00000174177 E002 1.3159170 0.0123331309 0.0801117164 0.290561487 16 88706503 88706521 19 + 0.464 0.195 -1.756
ENSG00000174177 E003 2.0328509 0.0079150455 0.0256952877 0.148049441 16 88706522 88706544 23 + 0.599 0.267 -1.809
ENSG00000174177 E004 3.4871430 0.0043468034 0.0317245428 0.168292662 16 88706545 88706588 44 + 0.753 0.474 -1.238
ENSG00000174177 E005 3.6130234 0.0039797041 0.0591048324 0.243936335 16 88706589 88706598 10 + 0.753 0.513 -1.046
ENSG00000174177 E006 1.0077143 0.5149642583 0.1697302135 0.441788668 16 88706599 88707135 537 + 0.083 0.474 3.224
ENSG00000174177 E007 2.6688533 0.0051577416 0.5069590460 0.765612329 16 88707136 88707210 75 + 0.599 0.513 -0.394
ENSG00000174177 E008 0.0000000       16 88709938 88709958 21 +      
ENSG00000174177 E009 0.0000000       16 88709959 88710016 58 +      
ENSG00000174177 E010 0.0000000       16 88710223 88710282 60 +      
ENSG00000174177 E011 1.3798410 0.0101377952 0.0093028152 0.076741822 16 88710283 88710908 626 + 0.154 0.549 2.584
ENSG00000174177 E012 6.4865654 0.0022926764 0.4019595693 0.685121114 16 88711635 88711695 61 + 0.828 0.921 0.359
ENSG00000174177 E013 2.5695407 0.0103810920 0.6960290944 0.876012320 16 88712061 88712273 213 + 0.523 0.583 0.276
ENSG00000174177 E014 12.9619885 0.0040976980 0.3261104432 0.618636019 16 88712274 88712383 110 + 1.103 1.188 0.305
ENSG00000174177 E015 25.2437697 0.0006461595 0.9743062293 0.995387733 16 88712622 88712905 284 + 1.412 1.422 0.035
ENSG00000174177 E016 14.6470580 0.0010519340 0.5770464024 0.810944308 16 88713312 88713447 136 + 1.170 1.218 0.173
ENSG00000174177 E017 0.7312884 0.4440625571 0.6888905178 0.871887670 16 88713480 88713646 167 + 0.213 0.267 0.416
ENSG00000174177 E018 15.7943157 0.0009451425 0.0970721767 0.324521754 16 88713647 88713778 132 + 1.164 1.287 0.436
ENSG00000174177 E019 12.2061236 0.0025353918 0.5911068647 0.819135602 16 88714136 88714227 92 + 1.095 1.146 0.183
ENSG00000174177 E020 13.2877909 0.0012292580 0.8838875635 0.960946438 16 88714383 88714486 104 + 1.144 1.163 0.068
ENSG00000174177 E021 1.1413356 0.0479093763 0.0003911027 0.007167426 16 88714487 88714586 100 + 0.000 0.549 13.149
ENSG00000174177 E022 12.0372008 0.0012807618 0.5410173260 0.788754054 16 88714587 88714681 95 + 1.131 1.090 -0.147
ENSG00000174177 E023 8.3844838 0.0062672476 0.4775547560 0.743836649 16 88714682 88714737 56 + 0.996 0.936 -0.224
ENSG00000174177 E024 8.1627599 0.0037825968 0.7871530962 0.918279509 16 88714860 88714926 67 + 0.967 0.950 -0.064
ENSG00000174177 E025 1.1225473 0.0116206203 0.0371090876 0.185529434 16 88714985 88715047 63 + 0.154 0.474 2.221
ENSG00000174177 E026 7.3780496 0.0019648173 0.0879043585 0.307519859 16 88715048 88715106 59 + 0.987 0.823 -0.622
ENSG00000174177 E027 0.7259635 0.0143157513 0.6197487648 0.835491168 16 88715107 88715181 75 + 0.267 0.195 -0.586
ENSG00000174177 E028 7.8478068 0.0021602734 0.0354777564 0.180327709 16 88715182 88715396 215 + 1.023 0.823 -0.756

Help

Please Click HERE to learn more details about the results from DEXseq.