ENSG00000174231

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000304992 ENSG00000174231 No_inf pgKDN_inf PRPF8 protein_coding protein_coding 65.93687 66.52712 61.40762 6.388131 4.629777 -0.1155069 14.358060 8.640913 17.1567812 0.8134331 1.0816043 0.9886953 0.2264750 0.131050 0.287350 0.156300 0.04774680 0.02267405 FALSE TRUE
ENST00000571958 ENSG00000174231 No_inf pgKDN_inf PRPF8 protein_coding protein_coding 65.93687 66.52712 61.40762 6.388131 4.629777 -0.1155069 12.673711 18.706859 6.5701498 5.6447112 6.5701498 -1.5081460 0.1664000 0.267175 0.089350 -0.177825 0.02267405 0.02267405 FALSE FALSE
ENST00000572723 ENSG00000174231 No_inf pgKDN_inf PRPF8 protein_coding retained_intron 65.93687 66.52712 61.40762 6.388131 4.629777 -0.1155069 2.379177 4.499684 0.7581421 1.1021237 0.1404327 -2.5535812 0.0365000 0.069275 0.012250 -0.057025 0.05984973 0.02267405 FALSE FALSE
ENST00000703539 ENSG00000174231 No_inf pgKDN_inf PRPF8 protein_coding protein_coding_CDS_not_defined 65.93687 66.52712 61.40762 6.388131 4.629777 -0.1155069 13.254121 9.807854 14.5956662 1.3046120 1.3684186 0.5730486 0.2070417 0.151050 0.240400 0.089350 0.45200222 0.02267405 FALSE TRUE
MSTRG.11807.3 ENSG00000174231 No_inf pgKDN_inf PRPF8 protein_coding   65.93687 66.52712 61.40762 6.388131 4.629777 -0.1155069 16.341944 16.749858 14.5792642 0.2249482 2.4919517 -0.2001028 0.2591083 0.257775 0.244925 -0.012850 0.93664942 0.02267405 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174231 E001 0.2441403 0.0163839209 8.580505e-01   17 1650629 1650629 1 - 0.086 0.105 0.332
ENSG00000174231 E002 1.1147106 0.0120773636 1.819735e-01 4.579766e-01 17 1650630 1650630 1 - 0.219 0.423 1.332
ENSG00000174231 E003 1.9945022 0.0069960608 1.363634e-02 9.828440e-02 17 1650631 1650651 21 - 0.272 0.633 1.917
ENSG00000174231 E004 1.9945022 0.0069960608 1.363634e-02 9.828440e-02 17 1650652 1650653 2 - 0.272 0.633 1.917
ENSG00000174231 E005 1.9945022 0.0069960608 1.363634e-02 9.828440e-02 17 1650654 1650658 5 - 0.272 0.633 1.917
ENSG00000174231 E006 1.9945022 0.0069960608 1.363634e-02 9.828440e-02 17 1650659 1650660 2 - 0.272 0.633 1.917
ENSG00000174231 E007 33.0713563 0.0005235328 3.385664e-02 1.751294e-01 17 1650661 1650801 141 - 1.477 1.587 0.375
ENSG00000174231 E008 24.4099704 0.0005721663 3.503189e-02 1.791420e-01 17 1650802 1650839 38 - 1.341 1.467 0.434
ENSG00000174231 E009 17.5029452 0.0086944961 4.022652e-01 6.854472e-01 17 1650840 1650846 7 - 1.234 1.300 0.231
ENSG00000174231 E010 52.9493519 0.0006270967 1.444800e-01 4.046964e-01 17 1650847 1650956 110 - 1.702 1.762 0.206
ENSG00000174231 E011 85.7230617 0.0001911102 5.304526e-05 1.401050e-03 17 1651108 1651310 203 - 1.872 2.002 0.436
ENSG00000174231 E012 55.1274945 0.0002829617 1.201121e-07 6.891623e-06 17 1651414 1651553 140 - 1.637 1.850 0.721
ENSG00000174231 E013 21.4267957 0.0008537444 5.499536e-04 9.401330e-03 17 1651648 1651662 15 - 1.234 1.454 0.767
ENSG00000174231 E014 55.9999162 0.0026058169 2.691932e-04 5.322093e-03 17 1651663 1651788 126 - 1.672 1.834 0.548
ENSG00000174231 E015 2.3742758 0.0760308965 9.113145e-03 7.563994e-02 17 1651789 1651980 192 - 0.272 0.709 2.239
ENSG00000174231 E016 1.1134844 0.0405179474 1.954876e-01 4.758820e-01 17 1651981 1652037 57 - 0.219 0.423 1.333
ENSG00000174231 E017 1.0045056 0.0143402875 1.176854e-02 8.945723e-02 17 1652038 1652146 109 - 0.086 0.466 3.140
ENSG00000174231 E018 4.8699621 0.0162776043 1.077307e-04 2.524554e-03 17 1652731 1653541 811 - 0.472 0.966 2.069
ENSG00000174231 E019 59.9015956 0.0002394413 5.299062e-03 5.171907e-02 17 1653542 1653683 142 - 1.731 1.838 0.362
ENSG00000174231 E020 86.0167863 0.0002110930 7.634928e-01 9.078324e-01 17 1653777 1654016 240 - 1.934 1.943 0.033
ENSG00000174231 E021 0.6358076 0.3697466080 5.493251e-02 2.334357e-01 17 1654017 1654980 964 - 0.000 0.375 12.916
ENSG00000174231 E022 73.9905816 0.0025060229 5.841040e-01 8.150858e-01 17 1655350 1655543 194 - 1.863 1.885 0.074
ENSG00000174231 E023 48.3297621 0.0003042034 5.630059e-01 8.026050e-01 17 1656392 1656502 111 - 1.680 1.705 0.084
ENSG00000174231 E024 30.5962901 0.0004450163 7.895602e-01 9.192420e-01 17 1656503 1656565 63 - 1.505 1.490 -0.049
ENSG00000174231 E025 41.6213458 0.0083542047 9.202626e-01 9.752146e-01 17 1656648 1656761 114 - 1.626 1.631 0.018
ENSG00000174231 E026 33.6583045 0.0014053550 8.012603e-01 9.258872e-01 17 1658253 1658381 129 - 1.544 1.531 -0.046
ENSG00000174231 E027 22.4937862 0.0006351515 3.090121e-01 6.023441e-01 17 1658526 1658603 78 - 1.398 1.334 -0.220
ENSG00000174231 E028 26.6138459 0.0005196499 1.762658e-01 4.504099e-01 17 1658604 1658682 79 - 1.474 1.396 -0.269
ENSG00000174231 E029 27.8588078 0.0004957564 3.273233e-01 6.198686e-01 17 1658683 1658763 81 - 1.484 1.428 -0.190
ENSG00000174231 E030 32.5515754 0.0004295280 8.834291e-01 9.608160e-01 17 1659357 1659463 107 - 1.528 1.520 -0.026
ENSG00000174231 E031 28.1670379 0.0004883387 8.685180e-01 9.548371e-01 17 1659464 1659548 85 - 1.468 1.458 -0.032
ENSG00000174231 E032 2.9939349 0.0070187806 2.682389e-03 3.171240e-02 17 1659549 1659840 292 - 0.363 0.774 1.917
ENSG00000174231 E033 39.1049921 0.0045868710 6.299083e-01 8.412568e-01 17 1659841 1660001 161 - 1.614 1.587 -0.093
ENSG00000174231 E034 34.4680308 0.0016947439 6.230337e-01 8.376975e-01 17 1660432 1660578 147 - 1.560 1.534 -0.089
ENSG00000174231 E035 35.5823912 0.0041072926 8.155204e-01 9.325223e-01 17 1660698 1660827 130 - 1.568 1.555 -0.045
ENSG00000174231 E036 0.0000000       17 1660927 1660992 66 -      
ENSG00000174231 E037 31.0497535 0.0005245736 5.401957e-01 7.883036e-01 17 1660993 1661162 170 - 1.519 1.487 -0.112
ENSG00000174231 E038 0.2542726 0.2967739638 2.329631e-01   17 1661163 1661270 108 - 0.000 0.190 11.687
ENSG00000174231 E039 29.1438749 0.0031618392 8.183918e-02 2.942609e-01 17 1661271 1661406 136 - 1.522 1.419 -0.353
ENSG00000174231 E040 30.0388423 0.0004743436 2.321176e-01 5.208233e-01 17 1661611 1661790 180 - 1.519 1.454 -0.223
ENSG00000174231 E041 37.3196785 0.0006412524 8.600821e-01 9.515052e-01 17 1661906 1662153 248 - 1.578 1.587 0.030
ENSG00000174231 E042 0.0000000       17 1669354 1669441 88 -      
ENSG00000174231 E043 0.0000000       17 1672941 1673080 140 -      
ENSG00000174231 E044 19.7918516 0.0006834595 1.494717e-01 4.117907e-01 17 1673081 1673197 117 - 1.358 1.263 -0.334
ENSG00000174231 E045 31.3929192 0.0037965396 6.269460e-01 8.397894e-01 17 1673357 1673567 211 - 1.496 1.524 0.096
ENSG00000174231 E046 22.3923860 0.0022019344 5.245403e-01 7.776618e-01 17 1673746 1673892 147 - 1.386 1.345 -0.142
ENSG00000174231 E047 18.4493857 0.0088359382 8.907226e-04 1.372970e-02 17 1674442 1674537 96 - 1.390 1.126 -0.930
ENSG00000174231 E048 17.2515720 0.0008487147 5.577577e-04 9.514236e-03 17 1674538 1674643 106 - 1.358 1.108 -0.885
ENSG00000174231 E049 8.1945498 0.0017424606 6.096360e-03 5.715298e-02 17 1674644 1674680 37 - 1.068 0.794 -1.034
ENSG00000174231 E050 26.0777711 0.0005496059 4.010639e-05 1.104185e-03 17 1675152 1675339 188 - 1.528 1.282 -0.852
ENSG00000174231 E051 0.3646686 0.2405091773 7.825415e-01   17 1675340 1675530 191 - 0.157 0.105 -0.668
ENSG00000174231 E052 20.3326207 0.0025212498 5.632554e-03 5.399683e-02 17 1675620 1675812 193 - 1.405 1.214 -0.668
ENSG00000174231 E053 15.5482336 0.0009058806 2.377335e-01 5.267136e-01 17 1675928 1676054 127 - 1.256 1.168 -0.309
ENSG00000174231 E054 10.7320758 0.0036607749 8.276732e-01 9.376309e-01 17 1676207 1676307 101 - 1.060 1.079 0.069
ENSG00000174231 E055 9.4914240 0.0433956596 7.633805e-01 9.077557e-01 17 1676308 1676370 63 - 1.034 1.003 -0.115
ENSG00000174231 E056 26.8025044 0.0088312038 5.268637e-02 2.280813e-01 17 1676505 1676711 207 - 1.499 1.366 -0.457
ENSG00000174231 E057 26.7373961 0.0133235789 2.602004e-01 5.528858e-01 17 1676976 1677172 197 - 1.477 1.396 -0.280
ENSG00000174231 E058 0.0000000       17 1677173 1677271 99 -      
ENSG00000174231 E059 15.7467313 0.0025603117 4.687551e-02 2.126669e-01 17 1677565 1677694 130 - 1.286 1.135 -0.536
ENSG00000174231 E060 0.1186381 0.0118445435 6.759609e-01   17 1678441 1678517 77 - 0.086 0.000 -10.563
ENSG00000174231 E061 14.0007861 0.0017975210 4.244127e-03 4.427538e-02 17 1678518 1678652 135 - 1.266 1.037 -0.820
ENSG00000174231 E062 16.1223644 0.0183012336 1.682865e-03 2.234457e-02 17 1678762 1678881 120 - 1.345 1.048 -1.057
ENSG00000174231 E063 4.1917437 0.0526987134 3.016956e-02 1.633598e-01 17 1679017 1679017 1 - 0.838 0.505 -1.421
ENSG00000174231 E064 14.9694800 0.0008611886 2.042303e-03 2.595418e-02 17 1679018 1679206 189 - 1.296 1.058 -0.846
ENSG00000174231 E065 9.0105887 0.0019471685 8.606674e-01 9.517246e-01 17 1679291 1679410 120 - 1.007 0.991 -0.060
ENSG00000174231 E066 14.8293037 0.0009218063 3.638250e-01 6.526487e-01 17 1679609 1679799 191 - 1.228 1.160 -0.243
ENSG00000174231 E067 0.6351783 0.0380363237 1.149184e-02 8.812753e-02 17 1680481 1680725 245 - 0.000 0.375 13.236
ENSG00000174231 E068 11.3877987 0.0064088329 9.003608e-02 3.116420e-01 17 1680726 1680831 106 - 1.156 1.003 -0.554
ENSG00000174231 E069 10.1467748 0.0018212268 1.378285e-02 9.897010e-02 17 1680929 1681054 126 - 1.135 0.911 -0.825
ENSG00000174231 E070 14.2007397 0.0020134845 1.074123e-01 3.435069e-01 17 1681478 1681690 213 - 1.234 1.108 -0.451
ENSG00000174231 E071 15.3624118 0.0008701404 8.903610e-01 9.633912e-01 17 1681820 1682038 219 - 1.217 1.207 -0.036
ENSG00000174231 E072 9.7710075 0.0016902968 7.544894e-03 6.646951e-02 17 1682129 1682293 165 - 1.128 0.880 -0.916
ENSG00000174231 E073 0.1271363 0.0123703535 4.262319e-01   17 1682392 1682460 69 - 0.000 0.105 10.976
ENSG00000174231 E074 1.2520704 0.0098646431 2.192619e-02 1.344538e-01 17 1683021 1683532 512 - 0.157 0.505 2.332
ENSG00000174231 E075 6.2960052 0.0021419274 1.613636e-01 4.294030e-01 17 1683533 1683701 169 - 0.925 0.774 -0.585
ENSG00000174231 E076 0.0000000       17 1684472 1684582 111 -      
ENSG00000174231 E077 0.0000000       17 1684583 1684779 197 -      
ENSG00000174231 E078 0.0000000       17 1684780 1684867 88 -      

Help

Please Click HERE to learn more details about the results from DEXseq.