ENSG00000174238

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000313486 ENSG00000174238 No_inf pgKDN_inf PITPNA protein_coding protein_coding 19.85721 17.44076 19.13715 0.9335067 1.160001 0.1338401 1.1047102 0.8527413 1.246992 0.2982471 1.2469917 0.5429751 0.06030000 0.051400 0.071525 0.020125 0.67656254 0.01270237 FALSE  
ENST00000572004 ENSG00000174238 No_inf pgKDN_inf PITPNA protein_coding retained_intron 19.85721 17.44076 19.13715 0.9335067 1.160001 0.1338401 0.5283160 1.0197832 0.000000 0.3043992 0.0000000 -6.6861968 0.02701667 0.057550 0.000000 -0.057550 0.01270237 0.01270237    
ENST00000575288 ENSG00000174238 No_inf pgKDN_inf PITPNA protein_coding nonsense_mediated_decay 19.85721 17.44076 19.13715 0.9335067 1.160001 0.1338401 5.5381101 4.7153659 5.778461 1.6900521 0.2226942 0.2927539 0.27585833 0.259375 0.304525 0.045150 0.86558664 0.01270237 TRUE  
ENST00000575895 ENSG00000174238 No_inf pgKDN_inf PITPNA protein_coding protein_coding 19.85721 17.44076 19.13715 0.9335067 1.160001 0.1338401 0.4211907 0.0000000 1.263572 0.0000000 1.2635720 6.9927367 0.01866667 0.000000 0.056000 0.056000 0.84294323 0.01270237 FALSE  
MSTRG.11856.2 ENSG00000174238 No_inf pgKDN_inf PITPNA protein_coding   19.85721 17.44076 19.13715 0.9335067 1.160001 0.1338401 10.9034791 10.0007380 10.848126 0.8428073 1.2879736 0.1172268 0.55839167 0.582925 0.567950 -0.014975 0.99500569 0.01270237 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174238 E001 0.0000000       17 1517718 1517958 241 -      
ENSG00000174238 E002 126.1614392 0.0025420821 0.201880924 0.48425884 17 1517959 1520212 2254 - 2.083 2.123 0.134
ENSG00000174238 E003 37.6372324 0.0004404664 0.587660190 0.81701260 17 1520213 1520538 326 - 1.570 1.602 0.107
ENSG00000174238 E004 20.3309162 0.0007493267 0.801924363 0.92610246 17 1521579 1521645 67 - 1.318 1.340 0.076
ENSG00000174238 E005 16.6002129 0.0128541175 0.424999297 0.70414488 17 1534099 1534168 70 - 1.275 1.215 -0.214
ENSG00000174238 E006 13.8123633 0.0032919642 0.565066723 0.80405356 17 1534169 1534221 53 - 1.190 1.151 -0.138
ENSG00000174238 E007 13.4764627 0.0011423482 0.944936201 0.98479806 17 1535182 1535261 80 - 1.154 1.166 0.041
ENSG00000174238 E008 8.0809953 0.0018833591 0.954197362 0.98875445 17 1535262 1535292 31 - 0.952 0.963 0.041
ENSG00000174238 E009 11.1634862 0.0013391073 0.554037490 0.79696639 17 1535441 1535470 30 - 1.056 1.111 0.200
ENSG00000174238 E010 10.1609021 0.0014623636 0.963090121 0.99213233 17 1535471 1535506 36 - 1.047 1.048 0.007
ENSG00000174238 E011 8.1732330 0.0054938000 0.435291414 0.71219830 17 1535507 1535518 12 - 0.997 0.927 -0.261
ENSG00000174238 E012 0.3731018 0.0168458812 0.575059972   17 1535785 1535841 57 - 0.094 0.175 1.041
ENSG00000174238 E013 0.8888863 0.0124369480 0.004210210 0.04402355 17 1538439 1538868 430 - 0.000 0.437 13.108
ENSG00000174238 E014 12.4225637 0.0012390083 0.185050039 0.46261652 17 1538869 1538952 84 - 1.176 1.076 -0.357
ENSG00000174238 E015 6.8059391 0.0023911001 0.200340952 0.48234808 17 1541566 1541586 21 - 0.952 0.827 -0.480
ENSG00000174238 E016 7.8097899 0.0034429731 0.665865296 0.86103188 17 1541587 1541640 54 - 0.964 0.927 -0.139
ENSG00000174238 E017 5.9819521 0.0025351233 0.707785485 0.88141807 17 1543020 1543027 8 - 0.862 0.827 -0.136
ENSG00000174238 E018 13.4433021 0.0010844500 0.756497028 0.90416473 17 1548296 1548387 92 - 1.169 1.151 -0.064
ENSG00000174238 E019 15.0266988 0.0010111381 0.575707507 0.81013929 17 1553004 1553149 146 - 1.222 1.188 -0.123
ENSG00000174238 E020 3.5756670 0.0475074760 0.407786885 0.69021825 17 1558529 1558559 31 - 0.591 0.718 0.544
ENSG00000174238 E021 0.7614676 0.0137692900 0.009074571 0.07547076 17 1559508 1559755 248 - 0.000 0.396 12.893
ENSG00000174238 E022 0.3716209 0.0167557848 0.575631271   17 1559756 1559801 46 - 0.094 0.175 1.041
ENSG00000174238 E023 0.4896324 0.0160594034 0.989569738   17 1561199 1561281 83 - 0.171 0.175 0.041
ENSG00000174238 E024 4.0038989 0.0201676099 0.148484403 0.41039038 17 1562541 1562655 115 - 0.783 0.600 -0.766
ENSG00000174238 E025 2.9063770 0.0061317842 0.110921476 0.34960489 17 1562656 1562792 137 - 0.687 0.475 -0.959

Help

Please Click HERE to learn more details about the results from DEXseq.