ENSG00000174243

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000308025 ENSG00000174243 No_inf pgKDN_inf DDX23 protein_coding protein_coding 20.89208 19.17064 21.46397 0.8095591 1.052508 0.162938 15.0660687 11.065133 17.6885332 1.0495709 0.7847190 0.6763058 0.71767500 0.579025 0.824875 0.245850 0.01812139 0.01812139 FALSE TRUE
ENST00000547165 ENSG00000174243 No_inf pgKDN_inf DDX23 protein_coding retained_intron 20.89208 19.17064 21.46397 0.8095591 1.052508 0.162938 0.8495379 1.495063 0.3484746 0.7506153 0.3484746 -2.0698808 0.04094167 0.074725 0.014700 -0.060025 0.49084095 0.01812139 TRUE TRUE
ENST00000551098 ENSG00000174243 No_inf pgKDN_inf DDX23 protein_coding retained_intron 20.89208 19.17064 21.46397 0.8095591 1.052508 0.162938 1.6417810 2.508569 0.8902417 0.4908770 0.3631793 -1.4842200 0.08243333 0.131725 0.044100 -0.087625 0.36538704 0.01812139 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174243 E001 0.0000000       12 48829756 48829763 8 -      
ENSG00000174243 E002 0.3628435 0.0165781115 0.64770583   12 48829764 48829770 7 - 0.166 0.100 -0.851
ENSG00000174243 E003 0.6071098 0.0180264671 0.73965079 0.89686991 12 48829771 48829784 14 - 0.230 0.181 -0.436
ENSG00000174243 E004 0.7342461 0.0416314521 0.90346612 0.96901965 12 48829785 48829787 3 - 0.230 0.249 0.149
ENSG00000174243 E005 0.8529493 0.0512617325 0.81720657 0.93355968 12 48829788 48829791 4 - 0.285 0.249 -0.266
ENSG00000174243 E006 1.7346270 0.0878362934 0.28489383 0.57862790 12 48829792 48829824 33 - 0.335 0.521 0.998
ENSG00000174243 E007 3.3232300 0.0044954418 0.40709503 0.68963783 12 48829825 48829876 52 - 0.579 0.687 0.471
ENSG00000174243 E008 7.4795106 0.0020557604 0.60645704 0.82867558 12 48829877 48829949 73 - 0.902 0.954 0.196
ENSG00000174243 E009 14.8048522 0.0012027734 0.92476786 0.97715075 12 48829950 48830056 107 - 1.194 1.203 0.030
ENSG00000174243 E010 59.8123874 0.0003289369 0.65109890 0.85302431 12 48830057 48830515 459 - 1.775 1.793 0.061
ENSG00000174243 E011 32.3503150 0.0005082033 0.28031815 0.57361153 12 48830516 48830692 177 - 1.494 1.551 0.193
ENSG00000174243 E012 14.3991235 0.0009308777 0.57346026 0.80885522 12 48831142 48831213 72 - 1.207 1.166 -0.145
ENSG00000174243 E013 14.6769326 0.0013418264 0.85448828 0.94870046 12 48831214 48831316 103 - 1.188 1.203 0.053
ENSG00000174243 E014 4.0579732 0.0802000491 0.39037551 0.67597077 12 48831317 48832002 686 - 0.629 0.771 0.590
ENSG00000174243 E015 0.1271363 0.0123633111 0.48708742   12 48832003 48832077 75 - 0.000 0.100 11.718
ENSG00000174243 E016 13.5672583 0.0033218023 0.95807968 0.98998140 12 48832078 48832186 109 - 1.161 1.166 0.019
ENSG00000174243 E017 7.7081024 0.0018958345 0.78855882 0.91890468 12 48832422 48832450 29 - 0.926 0.954 0.103
ENSG00000174243 E018 13.3900245 0.0010020088 0.16599336 0.43608037 12 48832451 48832522 72 - 1.101 1.210 0.388
ENSG00000174243 E019 8.7598752 0.0016479723 0.05026650 0.22152912 12 48832523 48832542 20 - 0.889 1.073 0.683
ENSG00000174243 E020 8.7010926 0.0016236955 0.59036502 0.81868571 12 48832543 48832569 27 - 0.961 1.012 0.190
ENSG00000174243 E021 5.4874087 0.0026875338 0.68415188 0.86923552 12 48832570 48832573 4 - 0.833 0.789 -0.173
ENSG00000174243 E022 0.2451451 0.0164828285 0.93791872   12 48832574 48832596 23 - 0.091 0.100 0.149
ENSG00000174243 E023 0.1186381 0.0118801578 0.59383002   12 48832597 48832915 319 - 0.091 0.000 -12.358
ENSG00000174243 E024 24.0128561 0.0006681633 0.27410368 0.56763548 12 48833277 48833519 243 - 1.428 1.365 -0.219
ENSG00000174243 E025 0.0000000       12 48833520 48833561 42 -      
ENSG00000174243 E026 12.8873407 0.0012898723 0.15296400 0.41727001 12 48834320 48834457 138 - 1.194 1.082 -0.402
ENSG00000174243 E027 6.8566139 0.0604269637 0.61134636 0.83087050 12 48834458 48834497 40 - 0.862 0.928 0.253
ENSG00000174243 E028 0.2457744 0.0164623655 0.93830949   12 48834498 48834897 400 - 0.091 0.100 0.149
ENSG00000174243 E029 0.2536433 0.0161011887 0.20998046   12 48835120 48835164 45 - 0.000 0.181 12.642
ENSG00000174243 E030 0.2536433 0.0161011887 0.20998046   12 48835165 48835214 50 - 0.000 0.181 12.642
ENSG00000174243 E031 0.6261805 0.0149371200 0.14127198 0.39981234 12 48835215 48835990 776 - 0.091 0.308 2.149
ENSG00000174243 E032 8.0117931 0.0018146651 0.04455608 0.20633909 12 48836121 48836175 55 - 0.848 1.043 0.734
ENSG00000174243 E033 12.6455253 0.0010576420 0.23092693 0.51938235 12 48836176 48836266 91 - 1.085 1.181 0.346
ENSG00000174243 E034 11.9198305 0.0027880377 0.19245767 0.47234909 12 48836569 48836641 73 - 1.161 1.053 -0.387
ENSG00000174243 E035 20.5418006 0.0061965476 0.87695600 0.95824730 12 48836642 48836771 130 - 1.327 1.340 0.046
ENSG00000174243 E036 13.0395051 0.0123285039 0.50971601 0.76749558 12 48836772 48836794 23 - 1.174 1.118 -0.203
ENSG00000174243 E037 0.2454921 0.0164332522 0.93841892   12 48836795 48836893 99 - 0.091 0.100 0.149
ENSG00000174243 E038 24.0987251 0.0088296322 0.16964330 0.44170116 12 48836894 48837025 132 - 1.443 1.350 -0.321
ENSG00000174243 E039 9.6234286 0.0016087098 0.42928299 0.70758453 12 48837026 48837037 12 - 1.059 0.990 -0.255
ENSG00000174243 E040 0.7356589 0.0552311242 0.90747664 0.97062657 12 48837038 48837280 243 - 0.230 0.249 0.149
ENSG00000174243 E041 9.5086176 0.0014924325 0.49027430 0.75291555 12 48837281 48837291 11 - 1.050 0.990 -0.223
ENSG00000174243 E042 20.1569175 0.0008018273 0.01271395 0.09386741 12 48837292 48837393 102 - 1.397 1.236 -0.560
ENSG00000174243 E043 1.1263572 0.1655634059 0.11787485 0.36264115 12 48837394 48837523 130 - 0.166 0.448 1.956
ENSG00000174243 E044 20.1801770 0.0007178667 0.06252878 0.25116760 12 48837524 48837657 134 - 1.380 1.262 -0.414
ENSG00000174243 E045 3.2356822 0.0045992485 0.00876985 0.07360614 12 48837658 48837941 284 - 0.419 0.771 1.590
ENSG00000174243 E046 9.8824564 0.0026577910 0.58670464 0.81685497 12 48837942 48838014 73 - 1.059 1.012 -0.173
ENSG00000174243 E047 7.8238248 0.0018066058 0.92084145 0.97524654 12 48838015 48838080 66 - 0.950 0.941 -0.031
ENSG00000174243 E048 0.0000000       12 48838081 48838538 458 -      
ENSG00000174243 E049 0.1187032 0.0118121351 0.59394415   12 48839434 48839551 118 - 0.091 0.000 -12.358
ENSG00000174243 E050 8.3072644 0.0188269772 0.79339364 0.92120668 12 48839844 48839909 66 - 0.982 0.954 -0.106
ENSG00000174243 E051 12.4665605 0.0125057034 0.81948105 0.93433729 12 48840013 48840106 94 - 1.139 1.118 -0.078
ENSG00000174243 E052 0.1272623 0.0123669416 0.48705583   12 48840107 48840128 22 - 0.000 0.100 11.718
ENSG00000174243 E053 0.0000000       12 48840129 48840151 23 -      
ENSG00000174243 E054 16.0019406 0.0009786025 0.69594224 0.87598191 12 48843940 48844050 111 - 1.243 1.217 -0.094
ENSG00000174243 E055 21.5595232 0.0006901319 0.50346713 0.76296701 12 48845574 48845782 209 - 1.332 1.374 0.149
ENSG00000174243 E056 0.1268540 0.0123209975 0.48712143   12 48847256 48847347 92 - 0.000 0.100 11.718
ENSG00000174243 E057 0.1268540 0.0123209975 0.48712143   12 48847348 48847350 3 - 0.000 0.100 11.718
ENSG00000174243 E058 5.8940189 0.0179957345 0.40333429 0.68635803 12 48852084 48852176 93 - 0.786 0.887 0.390
ENSG00000174243 E059 0.0000000       12 48852624 48852842 219 -      

Help

Please Click HERE to learn more details about the results from DEXseq.