ENSG00000174437

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000313432 ENSG00000174437 No_inf pgKDN_inf ATP2A2 protein_coding retained_intron 155.6226 101.0543 172.0146 2.827311 1.922996 0.7673413 8.933853 18.669856 3.327883 0.6394014 0.3275064 -2.4844779 0.07641667 0.18515 0.019350 -0.165800 8.956509e-15 8.956509e-15 FALSE TRUE
ENST00000539276 ENSG00000174437 No_inf pgKDN_inf ATP2A2 protein_coding protein_coding 155.6226 101.0543 172.0146 2.827311 1.922996 0.7673413 13.061657 5.637914 17.903809 0.2422384 0.8963204 1.6652820 0.08023333 0.05580 0.104200 0.048400 1.411302e-01 8.956509e-15 FALSE TRUE
ENST00000548169 ENSG00000174437 No_inf pgKDN_inf ATP2A2 protein_coding protein_coding 155.6226 101.0543 172.0146 2.827311 1.922996 0.7673413 86.938679 42.443896 98.090140 0.8893664 3.7938962 1.2083582 0.53705833 0.42095 0.569900 0.148950 6.561312e-03 8.956509e-15 FALSE TRUE
MSTRG.7164.5 ENSG00000174437 No_inf pgKDN_inf ATP2A2 protein_coding   155.6226 101.0543 172.0146 2.827311 1.922996 0.7673413 41.191554 27.008959 49.658396 0.3031046 2.7542067 0.8783561 0.26640000 0.26795 0.288875 0.020925 8.610854e-01 8.956509e-15 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174437 E001 0.3707734 1.658712e-02 3.299884e-01   12 110280756 110280964 209 + 0.076 0.211 1.714
ENSG00000174437 E002 0.4797798 1.528097e-02 6.008584e-01   12 110281116 110281246 131 + 0.197 0.118 -0.871
ENSG00000174437 E003 3.9444525 5.571157e-03 1.391975e-02 9.962153e-02 12 110281247 110281296 50 + 0.790 0.460 -1.456
ENSG00000174437 E004 13.4961473 1.785246e-03 3.479232e-02 1.782850e-01 12 110281297 110281622 326 + 1.212 1.043 -0.608
ENSG00000174437 E005 60.6474091 2.465186e-04 1.003800e-05 3.420023e-04 12 110281623 110281907 285 + 1.841 1.667 -0.590
ENSG00000174437 E006 0.1187032 1.180404e-02 9.138268e-01   12 110281908 110281918 11 + 0.076 0.000 -10.403
ENSG00000174437 E007 22.1454736 2.901611e-03 1.585585e-03 2.134188e-02 12 110282604 110282621 18 + 1.428 1.214 -0.748
ENSG00000174437 E008 43.3691167 3.267376e-04 3.230539e-05 9.184811e-04 12 110282713 110282795 83 + 1.705 1.510 -0.664
ENSG00000174437 E009 31.2294156 4.610243e-04 1.166924e-03 1.684605e-02 12 110292020 110292048 29 + 1.561 1.384 -0.608
ENSG00000174437 E010 48.5935139 3.098166e-04 1.046684e-02 8.271683e-02 12 110292049 110292124 76 + 1.726 1.617 -0.368
ENSG00000174437 E011 0.1271363 1.229408e-02 3.266613e-01   12 110295991 110296314 324 + 0.000 0.118 10.405
ENSG00000174437 E012 95.4012181 1.673576e-04 1.478046e-07 8.286582e-06 12 110296599 110296737 139 + 2.033 1.868 -0.555
ENSG00000174437 E013 75.9408935 1.241182e-03 1.928741e-09 1.557256e-07 12 110322992 110323072 81 + 1.955 1.722 -0.784
ENSG00000174437 E014 1.3706813 1.602393e-02 2.331767e-02 1.394911e-01 12 110325801 110326389 589 + 0.197 0.545 2.129
ENSG00000174437 E015 62.1239019 2.515643e-04 5.114106e-03 5.048027e-02 12 110326390 110326475 86 + 1.829 1.725 -0.354
ENSG00000174437 E016 93.3500164 2.527429e-04 3.832139e-02 1.889948e-01 12 110327553 110327686 134 + 1.988 1.928 -0.203
ENSG00000174437 E017 178.9972249 1.593896e-03 3.086802e-03 3.524207e-02 12 110327687 110328017 331 + 2.274 2.198 -0.255
ENSG00000174437 E018 3.2404699 1.061136e-02 4.937401e-04 8.648710e-03 12 110329399 110331971 2573 + 0.369 0.842 2.155
ENSG00000174437 E019 1.4966815 2.290790e-02 1.229938e-02 9.187742e-02 12 110331972 110332596 625 + 0.197 0.582 2.299
ENSG00000174437 E020 57.8554389 1.778289e-03 9.804662e-02 3.265637e-01 12 110332597 110332685 89 + 1.785 1.719 -0.223
ENSG00000174437 E021 66.9533353 8.226324e-04 5.544192e-02 2.346179e-01 12 110333181 110333283 103 + 1.849 1.780 -0.232
ENSG00000174437 E022 94.1905533 8.934182e-04 2.756066e-05 8.078569e-04 12 110334012 110334143 132 + 2.019 1.880 -0.465
ENSG00000174437 E023 0.1187032 1.180404e-02 9.138268e-01   12 110334144 110334291 148 + 0.076 0.000 -10.403
ENSG00000174437 E024 82.9439971 1.777065e-04 5.281699e-05 1.395704e-03 12 110339281 110339403 123 + 1.963 1.829 -0.450
ENSG00000174437 E025 135.4150531 1.755207e-04 1.777584e-04 3.798424e-03 12 110339503 110339721 219 + 2.161 2.066 -0.317
ENSG00000174437 E026 240.3543369 9.111595e-05 4.430794e-06 1.697233e-04 12 110340659 110340994 336 + 2.405 2.320 -0.284
ENSG00000174437 E027 208.6504734 8.812293e-05 1.607876e-04 3.493924e-03 12 110342228 110342448 221 + 2.340 2.266 -0.247
ENSG00000174437 E028 76.5456349 9.594114e-04 1.220744e-01 3.695715e-01 12 110343232 110343255 24 + 1.900 1.849 -0.171
ENSG00000174437 E029 174.8895171 4.897936e-04 9.604806e-02 3.227836e-01 12 110343256 110343434 179 + 2.249 2.215 -0.114
ENSG00000174437 E030 132.5330570 1.360762e-04 5.510065e-02 2.338407e-01 12 110344886 110344971 86 + 2.133 2.089 -0.150
ENSG00000174437 E031 1.4652755 9.500747e-02 7.996945e-01 9.248737e-01 12 110344972 110345247 276 + 0.369 0.409 0.227
ENSG00000174437 E032 173.6437860 3.219092e-03 6.103773e-03 5.720259e-02 12 110345249 110345382 134 + 2.264 2.180 -0.278
ENSG00000174437 E033 16.6148370 7.174500e-03 1.148436e-09 9.647935e-08 12 110345437 110346000 564 + 0.974 1.466 1.747
ENSG00000174437 E034 159.1856870 1.210952e-04 1.033337e-01 3.360184e-01 12 110346001 110346118 118 + 2.208 2.175 -0.110
ENSG00000174437 E035 168.0036032 1.039070e-04 8.821763e-01 9.604218e-01 12 110346201 110346321 121 + 2.217 2.221 0.013
ENSG00000174437 E036 860.6272916 7.060905e-05 3.883741e-02 1.906660e-01 12 110346322 110347392 1071 + 2.915 2.942 0.091
ENSG00000174437 E037 11.3962978 2.713861e-02 2.224417e-02 1.356226e-01 12 110347393 110347453 61 + 0.973 1.214 0.870
ENSG00000174437 E038 42.3102680 9.792317e-04 4.271510e-07 2.146658e-05 12 110347454 110347791 338 + 1.512 1.759 0.840
ENSG00000174437 E039 324.9896236 4.168875e-04 3.555842e-74 1.475237e-70 12 110347792 110350291 2500 + 2.338 2.675 1.123
ENSG00000174437 E040 208.6572227 2.084303e-03 3.482650e-33 2.318929e-30 12 110350292 110351093 802 + 2.144 2.485 1.137

Help

Please Click HERE to learn more details about the results from DEXseq.