ENSG00000174485

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000431932 ENSG00000174485 No_inf pgKDN_inf DENND4A protein_coding protein_coding 5.219182 6.500931 4.362079 1.142102 0.4453727 -0.5745443 0.6134752 0.000000 1.2786399 0.0000000 0.2477226 7.0097054 0.13075000 0.000000 0.287225 0.287225 0.0003387834 0.0003387834 FALSE TRUE
ENST00000443035 ENSG00000174485 No_inf pgKDN_inf DENND4A protein_coding protein_coding 5.219182 6.500931 4.362079 1.142102 0.4453727 -0.5745443 0.3860065 0.494337 0.6636825 0.4943370 0.6636825 0.4176808 0.06554167 0.079450 0.117175 0.037725 0.9670624007 0.0003387834 FALSE TRUE
ENST00000562540 ENSG00000174485 No_inf pgKDN_inf DENND4A protein_coding retained_intron 5.219182 6.500931 4.362079 1.142102 0.4453727 -0.5745443 1.1862945 2.803890 0.0000000 1.1211800 0.0000000 -8.1364221 0.16433333 0.382325 0.000000 -0.382325 0.0352240827 0.0003387834 FALSE FALSE
ENST00000635620 ENSG00000174485 No_inf pgKDN_inf DENND4A protein_coding protein_coding 5.219182 6.500931 4.362079 1.142102 0.4453727 -0.5745443 0.2853896 0.000000 0.0000000 0.0000000 0.0000000 0.0000000 0.07004167 0.000000 0.000000 0.000000   0.0003387834 FALSE TRUE
MSTRG.9830.2 ENSG00000174485 No_inf pgKDN_inf DENND4A protein_coding   5.219182 6.500931 4.362079 1.142102 0.4453727 -0.5745443 2.4174891 2.826621 2.1217352 0.5449074 0.7108251 -0.4121450 0.50779167 0.475700 0.542975 0.067275 0.9389709694 0.0003387834 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174485 E001 0.6154116 0.1435929707 0.713745440 0.88469305 15 65658046 65658437 392 - 0.176 0.235 0.522
ENSG00000174485 E002 0.5982683 0.0627938023 0.174446898 0.44817887 15 65659054 65659122 69 - 0.301 0.093 -2.063
ENSG00000174485 E003 32.4388872 0.0004642962 0.002369031 0.02892512 15 65659123 65661776 2654 - 1.440 1.587 0.504
ENSG00000174485 E004 3.3293383 0.0043787285 0.390266794 0.67584737 15 65661777 65661814 38 - 0.574 0.684 0.478
ENSG00000174485 E005 2.1047373 0.0066448796 0.257857220 0.55006825 15 65661815 65661820 6 - 0.398 0.560 0.812
ENSG00000174485 E006 2.2318736 0.0064157440 0.182458741 0.45884817 15 65661821 65661841 21 - 0.398 0.588 0.937
ENSG00000174485 E007 9.0255714 0.0017951223 0.037267562 0.18586912 15 65661842 65661987 146 - 0.890 1.080 0.706
ENSG00000174485 E008 6.2696054 0.0023787443 0.576952358 0.81085440 15 65664330 65664394 65 - 0.830 0.887 0.221
ENSG00000174485 E009 10.2971372 0.0048244415 0.967363771 0.99341205 15 65664560 65664722 163 - 1.051 1.053 0.006
ENSG00000174485 E010 0.1272623 0.0124024563 0.556826459   15 65664723 65664956 234 - 0.000 0.093 10.556
ENSG00000174485 E011 0.0000000       15 65665199 65665225 27 -      
ENSG00000174485 E012 7.5144495 0.0021351113 0.314016118 0.60711734 15 65665345 65665462 118 - 0.875 0.972 0.366
ENSG00000174485 E013 8.4574938 0.0018278182 0.966024308 0.99303626 15 65667449 65667703 255 - 0.978 0.972 -0.021
ENSG00000174485 E014 8.8107858 0.0017623273 0.686309203 0.87041811 15 65667925 65668123 199 - 1.011 0.972 -0.143
ENSG00000174485 E015 8.6741342 0.0018566011 0.444350042 0.71897433 15 65669779 65669925 147 - 1.021 0.950 -0.266
ENSG00000174485 E016 9.6720143 0.0163632072 0.648106151 0.85142528 15 65670013 65670188 176 - 1.051 1.004 -0.173
ENSG00000174485 E017 4.7769154 0.0534758866 0.890946054 0.96365730 15 65671792 65671886 95 - 0.779 0.744 -0.137
ENSG00000174485 E018 5.2596859 0.0034670922 0.559904907 0.80065281 15 65676445 65676634 190 - 0.830 0.763 -0.264
ENSG00000174485 E019 0.3812526 0.0161494534 0.110129970   15 65680635 65681314 680 - 0.000 0.235 11.973
ENSG00000174485 E020 8.0948470 0.0019794278 0.930151644 0.97949779 15 65690415 65690698 284 - 0.954 0.961 0.025
ENSG00000174485 E021 18.8388055 0.0008658981 0.455071794 0.72769930 15 65690699 65691457 759 - 1.322 1.272 -0.175
ENSG00000174485 E022 2.6298013 0.0059677699 0.001556513 0.02103464 15 65691458 65691511 54 - 0.741 0.292 -2.233
ENSG00000174485 E023 0.0000000       15 65696316 65696365 50 -      
ENSG00000174485 E024 3.7814870 0.0040751590 0.517804467 0.77324435 15 65696366 65696497 132 - 0.720 0.639 -0.343
ENSG00000174485 E025 3.5776646 0.0048436308 0.234460146 0.52352820 15 65697267 65697383 117 - 0.574 0.725 0.648
ENSG00000174485 E026 0.3721553 0.2219007067 0.653735120   15 65700544 65700672 129 - 0.097 0.170 0.938
ENSG00000174485 E027 0.0000000       15 65700673 65700675 3 -      
ENSG00000174485 E028 3.0731732 0.0046330644 0.619002592 0.83528536 15 65701051 65701192 142 - 0.574 0.639 0.285
ENSG00000174485 E029 2.0829630 0.1097082168 0.905417472 0.96971503 15 65701762 65701881 120 - 0.477 0.499 0.107
ENSG00000174485 E030 1.0878330 0.0114840340 0.291395957 0.58493932 15 65701882 65701890 9 - 0.398 0.235 -1.063
ENSG00000174485 E031 3.0448469 0.0065016996 0.491114016 0.75354064 15 65702305 65702511 207 - 0.653 0.560 -0.411
ENSG00000174485 E032 2.0836487 0.0565094287 0.897429126 0.96614521 15 65702873 65703008 136 - 0.477 0.499 0.108
ENSG00000174485 E033 2.7922781 0.0504349672 0.299943458 0.59289538 15 65706091 65706224 134 - 0.653 0.499 -0.700
ENSG00000174485 E034 0.0000000       15 65715075 65715477 403 -      
ENSG00000174485 E035 3.5167608 0.0070240716 0.166225186 0.43641342 15 65715478 65715623 146 - 0.741 0.560 -0.773
ENSG00000174485 E036 4.9344604 0.0061283004 0.260780682 0.55330517 15 65717778 65717996 219 - 0.699 0.829 0.522
ENSG00000174485 E037 2.9382580 0.0054324380 0.920516174 0.97521456 15 65722848 65722948 101 - 0.602 0.588 -0.063
ENSG00000174485 E038 2.7946352 0.0051628662 0.257255716 0.54952927 15 65729072 65729247 176 - 0.653 0.499 -0.700
ENSG00000174485 E039 2.4382069 0.0080682940 0.594876505 0.82182555 15 65729534 65729678 145 - 0.574 0.499 -0.352
ENSG00000174485 E040 1.5954603 0.0097165025 0.839700092 0.94251794 15 65731642 65731700 59 - 0.398 0.428 0.160
ENSG00000174485 E041 1.8411086 0.0094517460 0.857007116 0.94985454 15 65732752 65732818 67 - 0.439 0.465 0.130
ENSG00000174485 E042 3.6785463 0.3032817600 0.925199785 0.97741095 15 65737707 65737945 239 - 0.653 0.684 0.133
ENSG00000174485 E043 3.9976418 0.0048622763 0.094934516 0.32058961 15 65738706 65738875 170 - 0.796 0.588 -0.870
ENSG00000174485 E044 2.7734543 0.0054984704 0.047588788 0.21444178 15 65741715 65741784 70 - 0.699 0.428 -1.255
ENSG00000174485 E045 3.8973022 0.0531271467 0.519605512 0.77430093 15 65752379 65752628 250 - 0.740 0.639 -0.425
ENSG00000174485 E046 3.6511936 0.0070593005 0.412398891 0.69366355 15 65756140 65756472 333 - 0.720 0.614 -0.450
ENSG00000174485 E047 0.8535692 0.0567259298 0.682960333 0.86866227 15 65761360 65761366 7 - 0.301 0.235 -0.478
ENSG00000174485 E048 1.3249184 0.0098770868 0.113164176 0.35386112 15 65761367 65761438 72 - 0.477 0.235 -1.478
ENSG00000174485 E049 0.4713493 0.0162560071 0.041282943   15 65792010 65792293 284 - 0.301 0.000 -13.254

Help

Please Click HERE to learn more details about the results from DEXseq.