ENSG00000174606

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000360506 ENSG00000174606 No_inf pgKDN_inf ANGEL2 protein_coding protein_coding 17.48144 20.53048 17.07071 1.899433 1.003962 -0.266102 1.3249720 2.732104 0.4786544 0.9364544 0.3020542 -2.48839694 0.07157500 0.139675 0.028325 -0.111350 0.56353701 0.02809072 FALSE TRUE
ENST00000366962 ENSG00000174606 No_inf pgKDN_inf ANGEL2 protein_coding protein_coding 17.48144 20.53048 17.07071 1.899433 1.003962 -0.266102 3.0169421 2.696544 3.6317406 1.7661978 0.4830427 0.42817631 0.18568333 0.134925 0.219300 0.084375 0.62200089 0.02809072 FALSE TRUE
ENST00000460337 ENSG00000174606 No_inf pgKDN_inf ANGEL2 protein_coding protein_coding_CDS_not_defined 17.48144 20.53048 17.07071 1.899433 1.003962 -0.266102 0.9645687 0.520815 1.1664060 0.2229754 0.4206142 1.14810506 0.05999167 0.024400 0.069675 0.045275 0.62537809 0.02809072 FALSE TRUE
ENST00000473303 ENSG00000174606 No_inf pgKDN_inf ANGEL2 protein_coding protein_coding_CDS_not_defined 17.48144 20.53048 17.07071 1.899433 1.003962 -0.266102 2.5330201 3.558784 1.8050307 0.4274258 0.1611041 -0.97543860 0.14485000 0.177375 0.107525 -0.069850 0.69552100 0.02809072   FALSE
ENST00000481918 ENSG00000174606 No_inf pgKDN_inf ANGEL2 protein_coding protein_coding_CDS_not_defined 17.48144 20.53048 17.07071 1.899433 1.003962 -0.266102 0.9353543 0.000000 1.9336820 0.0000000 0.6667057 7.60264838 0.05763333 0.000000 0.113200 0.113200 0.02809072 0.02809072   FALSE
ENST00000498650 ENSG00000174606 No_inf pgKDN_inf ANGEL2 protein_coding protein_coding_CDS_not_defined 17.48144 20.53048 17.07071 1.899433 1.003962 -0.266102 4.5183085 5.011499 4.7314782 1.5438934 1.1146607 -0.08278114 0.24720833 0.230250 0.268800 0.038550 0.91146363 0.02809072   FALSE
MSTRG.2672.1 ENSG00000174606 No_inf pgKDN_inf ANGEL2 protein_coding   17.48144 20.53048 17.07071 1.899433 1.003962 -0.266102 3.7234558 4.986122 3.3237208 1.0680359 0.6475305 -0.58367541 0.20687500 0.237475 0.193175 -0.044300 0.85002744 0.02809072 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174606 E001 0.1268540 0.0123516949 0.8710738707   1 212992180 212992181 2 - 0.000 0.078 9.140
ENSG00000174606 E002 0.6101607 0.0283095845 0.3482259046 0.638708245 1 212992182 212992190 9 - 0.283 0.143 -1.232
ENSG00000174606 E003 95.8815853 0.0002070619 0.0436121072 0.203875015 1 212992191 212993991 1801 - 1.937 1.991 0.183
ENSG00000174606 E004 40.2625690 0.0004048111 0.0322107408 0.169798610 1 212993992 212994728 737 - 1.536 1.636 0.340
ENSG00000174606 E005 28.4984463 0.0036168053 0.0947734177 0.320272211 1 212994729 212995192 464 - 1.391 1.490 0.344
ENSG00000174606 E006 8.8631563 0.0020146866 0.4801167534 0.745576487 1 212997155 212997199 45 - 1.021 0.955 -0.243
ENSG00000174606 E007 11.1288816 0.0014325316 0.6509761842 0.853024314 1 212997200 212997318 119 - 1.046 1.085 0.142
ENSG00000174606 E008 7.8465183 0.0020413585 0.0461891169 0.210756000 1 213000326 213000383 58 - 0.793 1.000 0.789
ENSG00000174606 E009 3.3471254 0.0534773783 0.6367057194 0.844885635 1 213000384 213000570 187 - 0.575 0.655 0.353
ENSG00000174606 E010 8.6673184 0.0026377469 0.5781352856 0.811480768 1 213000786 213000912 127 - 0.937 0.991 0.201
ENSG00000174606 E011 18.8768494 0.0029466031 0.0422024183 0.200012762 1 213000913 213002234 1322 - 1.187 1.333 0.513
ENSG00000174606 E012 7.2240350 0.0049497651 0.1224094173 0.370151912 1 213005033 213005124 92 - 0.995 0.837 -0.598
ENSG00000174606 E013 18.7919044 0.0058333761 0.1131578208 0.353861125 1 213005125 213005454 330 - 1.351 1.236 -0.401
ENSG00000174606 E014 2.3156425 0.0513948250 0.1295800202 0.381891516 1 213006539 213007128 590 - 0.640 0.409 -1.107
ENSG00000174606 E015 6.8556267 0.0022859718 0.0953187833 0.321408144 1 213007129 213007198 70 - 0.981 0.811 -0.647
ENSG00000174606 E016 15.2618713 0.0024807018 0.0005315626 0.009159519 1 213008210 213008466 257 - 1.339 1.085 -0.901
ENSG00000174606 E017 0.5073513 0.0157968495 0.1184131258 0.363509222 1 213011208 213011463 256 - 0.000 0.251 13.038
ENSG00000174606 E018 17.5912155 0.0012811834 0.0003703260 0.006882551 1 213013093 213013418 326 - 1.391 1.149 -0.847
ENSG00000174606 E019 7.0696274 0.0041747112 0.0142816708 0.101578219 1 213015226 213015608 383 - 1.033 0.784 -0.946
ENSG00000174606 E020 0.0000000       1 213015609 213015612 4 -      
ENSG00000174606 E021 1.7116807 0.0190009648 0.4197788825 0.699207976 1 213015613 213015653 41 - 0.497 0.375 -0.646
ENSG00000174606 E022 2.1020593 0.0082782843 0.7561031725 0.903858215 1 213015654 213015867 214 - 0.453 0.499 0.228

Help

Please Click HERE to learn more details about the results from DEXseq.