ENSG00000174695

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000502346 ENSG00000174695 No_inf pgKDN_inf TMEM167A protein_coding protein_coding 74.94274 59.2054 96.73964 2.244288 6.6948 0.7082838 27.23177 29.195202 30.04393 0.2428057 0.9895116 0.04132841 0.3794250 0.494975 0.313550 -0.181425 0.007001806 0.007001806 FALSE FALSE
ENST00000503892 ENSG00000174695 No_inf pgKDN_inf TMEM167A protein_coding protein_coding_CDS_not_defined 74.94274 59.2054 96.73964 2.244288 6.6948 0.7082838 17.78208 10.610668 23.60547 3.1253039 2.8383976 1.15285755 0.2325500 0.178125 0.245000 0.066875 0.689793089 0.007001806   FALSE
ENST00000504622 ENSG00000174695 No_inf pgKDN_inf TMEM167A protein_coding protein_coding_CDS_not_defined 74.94274 59.2054 96.73964 2.244288 6.6948 0.7082838 13.38222 12.318001 20.07951 7.1121136 4.7188396 0.70450341 0.1742833 0.200700 0.208225 0.007525 0.827978721 0.007001806   FALSE
ENST00000511118 ENSG00000174695 No_inf pgKDN_inf TMEM167A protein_coding retained_intron 74.94274 59.2054 96.73964 2.244288 6.6948 0.7082838 16.54668 7.081529 23.01073 4.1552289 5.7529120 1.69876490 0.2137417 0.126175 0.233250 0.107075 0.677902399 0.007001806   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174695 E001 179.3961421 1.459147e-03 2.098630e-05 0.0006409260 5 83052846 83054061 1216 - 2.197 2.306 0.362
ENSG00000174695 E002 347.8371615 7.691805e-05 4.253107e-02 0.2010092020 5 83054062 83056534 2473 - 2.526 2.558 0.105
ENSG00000174695 E003 62.8277111 1.432871e-02 4.378298e-01 0.7140584277 5 83056535 83056726 192 - 1.777 1.830 0.177
ENSG00000174695 E004 26.5856107 5.767051e-04 8.476029e-01 0.9459829177 5 83056727 83056766 40 - 1.432 1.448 0.055
ENSG00000174695 E005 55.3514257 2.737514e-04 1.241293e-02 0.0923546793 5 83056767 83056883 117 - 1.796 1.703 -0.316
ENSG00000174695 E006 113.4375407 1.741369e-04 1.987869e-05 0.0006154634 5 83056884 83057154 271 - 2.111 2.002 -0.367
ENSG00000174695 E007 29.2616962 8.035677e-03 1.214101e-01 0.3687790152 5 83061877 83061911 35 - 1.526 1.433 -0.321
ENSG00000174695 E008 0.0000000       5 83061912 83061975 64 -      
ENSG00000174695 E009 40.2968433 3.485773e-04 3.618068e-03 0.0396458528 5 83065008 83065117 110 - 1.677 1.547 -0.442
ENSG00000174695 E010 0.1272623 1.239211e-02 5.304046e-01   5 83071363 83071430 68 - 0.000 0.096 9.562
ENSG00000174695 E011 20.5449765 7.217340e-04 9.614242e-03 0.0783521524 5 83077321 83077453 133 - 1.408 1.247 -0.564
ENSG00000174695 E012 0.1187032 1.185695e-02 5.462493e-01   5 83077718 83077863 146 - 0.094 0.000 -10.229

Help

Please Click HERE to learn more details about the results from DEXseq.