ENSG00000174748

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000307839 ENSG00000174748 No_inf pgKDN_inf RPL15 protein_coding protein_coding 396.4041 461.7488 399.7542 1.930405 6.045606 -0.2079902 329.24157 398.02823 322.19499 4.938940 5.786101 -0.3049282 0.82813333 0.862025 0.806000 -0.056025 0.02675883 0.02675883 FALSE  
ENST00000413699 ENSG00000174748 No_inf pgKDN_inf RPL15 protein_coding protein_coding 396.4041 461.7488 399.7542 1.930405 6.045606 -0.2079902 32.65284 32.36475 36.97703 2.706455 4.750755 0.1921501 0.08334167 0.070025 0.092775 0.022750 0.70528473 0.02675883 FALSE  
ENST00000644185 ENSG00000174748 No_inf pgKDN_inf RPL15 protein_coding protein_coding 396.4041 461.7488 399.7542 1.930405 6.045606 -0.2079902 22.81156 18.79123 31.53657 3.832047 7.439290 0.7466564 0.05818333 0.040775 0.078525 0.037750 0.40375000 0.02675883 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174748 E001 0.0000000       3 23916591 23916768 178 +      
ENSG00000174748 E002 0.0000000       3 23916804 23916978 175 +      
ENSG00000174748 E003 0.3700180 2.194206e-01 7.581481e-01   3 23916979 23917095 117 + 0.104 0.160 0.721
ENSG00000174748 E004 1.4439700 1.014074e-02 3.786410e-02 1.877678e-01 3 23917096 23917131 36 + 0.535 0.222 -1.864
ENSG00000174748 E005 7.7236093 1.268464e-02 1.861797e-04 3.942448e-03 3 23917132 23917137 6 + 1.118 0.718 -1.523
ENSG00000174748 E006 8.3429261 1.865296e-03 1.446387e-04 3.206306e-03 3 23917138 23917138 1 + 1.136 0.770 -1.374
ENSG00000174748 E007 30.8591594 5.186727e-04 7.501154e-12 8.626167e-10 3 23917139 23917146 8 + 1.671 1.299 -1.279
ENSG00000174748 E008 30.9860134 5.394388e-04 1.267937e-11 1.418774e-09 3 23917147 23917147 1 + 1.671 1.303 -1.262
ENSG00000174748 E009 192.4295727 9.601397e-05 1.611194e-05 5.132790e-04 3 23917148 23917173 26 + 2.333 2.240 -0.309
ENSG00000174748 E010 21.8242988 6.120010e-04 4.258510e-03 4.435660e-02 3 23917174 23917239 66 + 1.447 1.268 -0.619
ENSG00000174748 E011 6.9407830 1.789259e-02 1.370810e-01 3.941004e-01 3 23917240 23917295 56 + 0.983 0.817 -0.635
ENSG00000174748 E012 0.2536433 1.602946e-02 3.176459e-01   3 23917296 23917298 3 + 0.000 0.160 8.836
ENSG00000174748 E013 2.2026013 6.230312e-03 6.798133e-01 8.677092e-01 3 23917299 23917444 146 + 0.535 0.477 -0.279
ENSG00000174748 E014 1.9493428 7.853845e-03 3.787816e-01 6.656416e-01 3 23917445 23917532 88 + 0.535 0.407 -0.642
ENSG00000174748 E015 2.0624755 1.441562e-01 4.155662e-01 6.956931e-01 3 23917533 23917665 133 + 0.567 0.407 -0.792
ENSG00000174748 E016 0.7321359 1.423681e-02 8.113781e-01 9.305245e-01 3 23917666 23917704 39 + 0.257 0.222 -0.279
ENSG00000174748 E017 3.2013441 4.384548e-03 7.791950e-01 9.149984e-01 3 23917705 23917836 132 + 0.598 0.637 0.168
ENSG00000174748 E018 2.2105703 3.962683e-02 9.496330e-01 9.868879e-01 3 23917837 23917849 13 + 0.499 0.508 0.043
ENSG00000174748 E019 194.2615573 9.874421e-05 3.756954e-07 1.915195e-05 3 23917850 23917946 97 + 2.345 2.236 -0.363
ENSG00000174748 E020 46.5911738 8.675386e-03 3.281010e-02 1.717299e-01 3 23917947 23917972 26 + 1.740 1.615 -0.424
ENSG00000174748 E021 352.2560366 9.347193e-05 1.564474e-03 2.112098e-02 3 23917973 23918031 59 + 2.572 2.522 -0.165
ENSG00000174748 E022 1.2176762 3.956673e-02 3.651571e-01 6.536563e-01 3 23918032 23918439 408 + 0.418 0.276 -0.864
ENSG00000174748 E023 868.5305494 3.415860e-05 4.570436e-02 2.093143e-01 3 23918440 23918576 137 + 2.945 2.928 -0.059
ENSG00000174748 E024 8.9064894 1.508723e-03 1.006600e-01 3.312130e-01 3 23918577 23918583 7 + 1.071 0.921 -0.557
ENSG00000174748 E025 7.4157600 2.185159e-03 1.634184e-02 1.111311e-01 3 23918584 23919195 612 + 1.040 0.802 -0.904
ENSG00000174748 E026 567.2327828 6.450361e-05 9.619718e-01 9.916848e-01 3 23919196 23919202 7 + 2.750 2.751 0.004
ENSG00000174748 E027 666.9013355 5.512307e-05 6.626544e-01 8.593937e-01 3 23919203 23919246 44 + 2.823 2.819 -0.011
ENSG00000174748 E028 2695.4318220 5.008952e-05 2.747202e-24 1.058340e-21 3 23919247 23920989 1743 + 3.399 3.447 0.162
ENSG00000174748 E029 4.3427134 6.381148e-03 1.079816e-01 3.445738e-01 3 23921598 23924374 2777 + 0.598 0.802 0.846

Help

Please Click HERE to learn more details about the results from DEXseq.