ENSG00000174842

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000370360 ENSG00000174842 No_inf pgKDN_inf GLMN protein_coding protein_coding 26.0739 40.60851 21.08243 1.727764 1.350204 -0.9454121 15.9975385 19.2618717 16.418300 1.6915101 2.6179628 -0.2303135 0.66570833 0.477275 0.764175 0.286900 0.078196049 0.000300354 FALSE TRUE
ENST00000471465 ENSG00000174842 No_inf pgKDN_inf GLMN protein_coding retained_intron 26.0739 40.60851 21.08243 1.727764 1.350204 -0.9454121 6.4878741 14.1940548 2.141932 1.0684295 0.1785373 -2.7225985 0.21180833 0.348675 0.102800 -0.245875 0.000300354 0.000300354   FALSE
ENST00000495852 ENSG00000174842 No_inf pgKDN_inf GLMN protein_coding protein_coding 26.0739 40.60851 21.08243 1.727764 1.350204 -0.9454121 1.2847349 3.8542048 0.000000 1.7263409 0.0000000 -8.5940278 0.03123333 0.093700 0.000000 -0.093700 0.083537069 0.000300354 FALSE TRUE
MSTRG.1345.2 ENSG00000174842 No_inf pgKDN_inf GLMN protein_coding   26.0739 40.60851 21.08243 1.727764 1.350204 -0.9454121 0.8580205 0.9140774 1.659984 0.3080751 1.6599840 0.8537486 0.03904167 0.021925 0.095200 0.073275 0.824020795 0.000300354 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174842 E001 4.715786 0.0103280896 3.771074e-01 6.641711e-01 1 92246402 92246484 83 - 0.673 0.781 0.443
ENSG00000174842 E002 3.682075 0.0039122744 3.762856e-01 6.634603e-01 1 92246485 92246489 5 - 0.726 0.613 -0.480
ENSG00000174842 E003 3.193007 0.0044950300 4.407078e-01 7.163737e-01 1 92246490 92246491 2 - 0.673 0.570 -0.450
ENSG00000174842 E004 19.524284 0.0191389585 8.675176e-01 9.544428e-01 1 92246492 92246646 155 - 1.291 1.301 0.035
ENSG00000174842 E005 20.012106 0.0153809280 5.957445e-02 2.447476e-01 1 92247062 92247144 83 - 1.200 1.360 0.563
ENSG00000174842 E006 30.387231 0.0005483631 3.336839e-02 1.736650e-01 1 92247878 92247989 112 - 1.405 1.521 0.398
ENSG00000174842 E007 16.489102 0.0008821715 1.104352e-11 1.246070e-09 1 92247990 92248408 419 - 0.774 1.367 2.173
ENSG00000174842 E008 10.124616 0.0015631758 8.788592e-01 9.590124e-01 1 92262863 92262864 2 - 1.024 1.037 0.045
ENSG00000174842 E009 18.146324 0.0032008809 9.754523e-01 9.956827e-01 1 92262865 92262926 62 - 1.270 1.266 -0.014
ENSG00000174842 E010 22.983856 0.0006156984 7.789534e-01 9.149984e-01 1 92263623 92263732 110 - 1.355 1.371 0.056
ENSG00000174842 E011 16.400166 0.0082327561 5.307617e-01 7.816323e-01 1 92264554 92264638 85 - 1.255 1.207 -0.169
ENSG00000174842 E012 11.846966 0.0013469869 8.435259e-01 9.441091e-01 1 92266419 92266492 74 - 1.105 1.088 -0.063
ENSG00000174842 E013 1.741080 0.0267773947 4.480257e-01 7.221675e-01 1 92266540 92266593 54 - 0.349 0.468 0.649
ENSG00000174842 E014 10.880851 0.0036725695 6.740554e-01 8.649499e-01 1 92266700 92266741 42 - 1.037 1.074 0.134
ENSG00000174842 E015 18.455664 0.0016422418 2.406236e-01 5.298471e-01 1 92267913 92268002 90 - 1.324 1.242 -0.286
ENSG00000174842 E016 9.711758 0.0139390980 3.510906e-01 6.414106e-01 1 92268105 92268135 31 - 1.072 0.979 -0.342
ENSG00000174842 E017 15.185446 0.0052888189 9.281660e-01 9.787035e-01 1 92269723 92269776 54 - 1.200 1.191 -0.029
ENSG00000174842 E018 27.731053 0.0043794030 4.385506e-01 7.147152e-01 1 92271465 92271652 188 - 1.473 1.425 -0.168
ENSG00000174842 E019 14.509559 0.0082576043 3.423065e-01 6.337129e-01 1 92286490 92286592 103 - 1.224 1.146 -0.279
ENSG00000174842 E020 30.091501 0.0204352387 1.469434e-01 4.080021e-01 1 92288914 92289151 238 - 1.544 1.434 -0.377
ENSG00000174842 E021 19.467366 0.0007297046 4.120468e-03 4.337107e-02 1 92290198 92290306 109 - 1.405 1.218 -0.655
ENSG00000174842 E022 20.319890 0.0010582416 3.980380e-01 6.821232e-01 1 92291418 92291537 120 - 1.349 1.292 -0.196
ENSG00000174842 E023 15.174291 0.0009095423 7.805266e-01 9.153888e-01 1 92297404 92297520 117 - 1.208 1.186 -0.078
ENSG00000174842 E024 6.417834 0.0026382219 7.934410e-01 9.212203e-01 1 92297521 92297529 9 - 0.874 0.846 -0.111
ENSG00000174842 E025 1.612425 0.0236909942 5.626369e-01 8.023772e-01 1 92297530 92297960 431 - 0.349 0.438 0.497
ENSG00000174842 E026 8.259541 0.0407378408 6.605334e-01 8.583058e-01 1 92297961 92298029 69 - 0.985 0.932 -0.196
ENSG00000174842 E027 3.708004 0.0934202740 9.548555e-01 9.889918e-01 1 92298925 92298987 63 - 0.644 0.670 0.115

Help

Please Click HERE to learn more details about the results from DEXseq.