ENSG00000174939

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000308748 ENSG00000174939 No_inf pgKDN_inf ASPHD1 protein_coding protein_coding 27.47097 14.66638 28.4861 1.594081 3.202664 0.957269 2.889212 0.4958606 4.074344 0.4958606 1.269027 3.0132926 0.09643333 0.045400 0.140725 0.095325 0.21360574 0.03463478 FALSE TRUE
ENST00000414952 ENSG00000174939 No_inf pgKDN_inf ASPHD1 protein_coding nonsense_mediated_decay 27.47097 14.66638 28.4861 1.594081 3.202664 0.957269 2.443821 1.5010422 1.714665 0.5308706 0.867553 0.1907722 0.09815000 0.114875 0.066975 -0.047900 0.85030232 0.03463478 TRUE TRUE
ENST00000483405 ENSG00000174939 No_inf pgKDN_inf ASPHD1 protein_coding protein_coding 27.47097 14.66638 28.4861 1.594081 3.202664 0.957269 6.673536 5.6279979 4.291913 0.9660034 1.404772 -0.3902044 0.28345000 0.407950 0.175200 -0.232750 0.41042054 0.03463478 FALSE FALSE
ENST00000563177 ENSG00000174939 No_inf pgKDN_inf ASPHD1 protein_coding protein_coding 27.47097 14.66638 28.4861 1.594081 3.202664 0.957269 4.720083 0.7798029 8.624415 0.7798029 1.154232 3.4505338 0.15808333 0.053200 0.305325 0.252125 0.03463478 0.03463478 TRUE FALSE
ENST00000651383 ENSG00000174939 No_inf pgKDN_inf ASPHD1 protein_coding protein_coding 27.47097 14.66638 28.4861 1.594081 3.202664 0.957269 10.154183 5.7529485 9.148179 2.4005480 3.331485 0.6682537 0.34326667 0.351375 0.291450 -0.059925 0.97145058 0.03463478 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174939 E001 0.0000000       16 29900375 29900378 4 +      
ENSG00000174939 E002 1.3396213 0.0370285255 0.58821050 0.81722178 16 29900379 29900487 109 + 0.328 0.414 0.501
ENSG00000174939 E003 2.2879175 0.0067743038 0.32274360 0.61566856 16 29900488 29900566 79 + 0.560 0.414 -0.722
ENSG00000174939 E004 7.5571384 0.0021392220 0.28863863 0.58217785 16 29900567 29900741 175 + 0.879 0.983 0.389
ENSG00000174939 E005 1.5620726 0.0100651543 0.28137188 0.57469934 16 29900742 29900857 116 + 0.459 0.292 -0.973
ENSG00000174939 E006 1.0913875 0.0125156068 0.81790288 0.93370248 16 29900858 29900881 24 + 0.328 0.292 -0.236
ENSG00000174939 E007 0.9641252 0.0126534926 0.47138264 0.73871313 16 29900882 29900920 39 + 0.328 0.214 -0.821
ENSG00000174939 E008 14.3401702 0.0010292783 0.01324167 0.09643212 16 29900921 29901551 631 + 1.239 1.049 -0.679
ENSG00000174939 E009 21.8109652 0.0012551652 0.42509877 0.70419605 16 29901552 29901743 192 + 1.365 1.318 -0.165
ENSG00000174939 E010 22.0131873 0.0007896938 0.32184330 0.61486651 16 29901744 29901920 177 + 1.328 1.385 0.199
ENSG00000174939 E011 20.2623913 0.0008768803 0.03047041 0.16424059 16 29904852 29904965 114 + 1.262 1.391 0.449
ENSG00000174939 E012 18.2060150 0.0016867673 0.93862154 0.98227560 16 29905788 29905959 172 + 1.271 1.276 0.016
ENSG00000174939 E013 2.8952441 0.0067832686 0.41508627 0.69523502 16 29905960 29906056 97 + 0.623 0.510 -0.517
ENSG00000174939 E014 0.6100306 0.3418356090 0.80746474 0.92894357 16 29906079 29906127 49 + 0.194 0.214 0.177
ENSG00000174939 E015 0.0000000       16 29919531 29919864 334 +      

Help

Please Click HERE to learn more details about the results from DEXseq.