ENSG00000174953

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000308361 ENSG00000174953 No_inf pgKDN_inf DHX36 protein_coding protein_coding 39.17757 32.36674 46.21878 3.103269 3.801817 0.5138335 11.259520 6.034564 15.603282 0.2097981 1.2013885 1.3690637 0.28345000 0.191425 0.344250 0.152825 0.18456652 0.01066891 FALSE  
ENST00000469977 ENSG00000174953 No_inf pgKDN_inf DHX36 protein_coding protein_coding 39.17757 32.36674 46.21878 3.103269 3.801817 0.5138335 1.006884 3.020651 0.000000 1.0926145 0.0000000 -8.2434839 0.02837500 0.085125 0.000000 -0.085125 0.01066891 0.01066891 FALSE  
ENST00000479934 ENSG00000174953 No_inf pgKDN_inf DHX36 protein_coding nonsense_mediated_decay 39.17757 32.36674 46.21878 3.103269 3.801817 0.5138335 11.451441 7.888342 11.939793 2.8628092 1.6973065 0.5973639 0.28365000 0.221750 0.257100 0.035350 0.86162539 0.01066891 TRUE  
ENST00000481332 ENSG00000174953 No_inf pgKDN_inf DHX36 protein_coding retained_intron 39.17757 32.36674 46.21878 3.103269 3.801817 0.5138335 3.241070 1.205570 6.693052 1.2055703 2.2538559 2.4631847 0.07077500 0.033150 0.133825 0.100675 0.31904588 0.01066891 FALSE  
ENST00000481941 ENSG00000174953 No_inf pgKDN_inf DHX36 protein_coding protein_coding 39.17757 32.36674 46.21878 3.103269 3.801817 0.5138335 1.911653 1.129202 1.663477 1.1292018 0.9702695 0.5548255 0.05573333 0.048525 0.040900 -0.007625 0.83649832 0.01066891 FALSE  
ENST00000495598 ENSG00000174953 No_inf pgKDN_inf DHX36 protein_coding retained_intron 39.17757 32.36674 46.21878 3.103269 3.801817 0.5138335 4.882845 7.240633 5.000117 2.0628565 1.5538497 -0.5332627 0.13149167 0.231150 0.104375 -0.126775 0.58077695 0.01066891 FALSE  
ENST00000496811 ENSG00000174953 No_inf pgKDN_inf DHX36 protein_coding protein_coding 39.17757 32.36674 46.21878 3.103269 3.801817 0.5138335 3.456256 3.458968 3.763930 0.2453091 0.2900057 0.1215613 0.09214167 0.110650 0.084750 -0.025900 0.83912901 0.01066891 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174953 E001 54.9726741 0.0003771464 1.059101e-07 6.142102e-06 3 154272546 154275667 3122 - 1.642 1.851 0.707
ENSG00000174953 E002 30.3042927 0.0005235404 1.931531e-01 4.729759e-01 3 154275668 154276028 361 - 1.518 1.449 -0.240
ENSG00000174953 E003 23.4532386 0.0006002077 2.221696e-02 1.355486e-01 3 154276029 154276170 142 - 1.437 1.296 -0.491
ENSG00000174953 E004 32.2184806 0.0004697296 8.995757e-01 9.672541e-01 3 154276171 154276356 186 - 1.518 1.513 -0.019
ENSG00000174953 E005 0.2451451 0.0161938771 7.621822e-01   3 154276553 154276746 194 - 0.080 0.113 0.565
ENSG00000174953 E006 25.1353624 0.0088476015 2.298969e-01 5.183912e-01 3 154276747 154276899 153 - 1.375 1.458 0.285
ENSG00000174953 E007 13.6987264 0.0022747016 9.962641e-02 3.297889e-01 3 154277598 154277624 27 - 1.103 1.232 0.462
ENSG00000174953 E008 12.5443966 0.0012615774 6.304217e-01 8.414996e-01 3 154277625 154277634 10 - 1.110 1.149 0.142
ENSG00000174953 E009 22.8295056 0.0006198296 1.176647e-01 3.623667e-01 3 154277635 154277718 84 - 1.329 1.425 0.334
ENSG00000174953 E010 1.9791976 0.0086461515 7.908769e-02 2.883822e-01 3 154277719 154277894 176 - 0.344 0.600 1.302
ENSG00000174953 E011 11.3494295 0.0032389421 5.571650e-04 9.509538e-03 3 154278495 154280578 2084 - 0.937 1.232 1.072
ENSG00000174953 E012 17.5456522 0.0084614480 5.539029e-01 7.968579e-01 3 154280579 154280669 91 - 1.243 1.289 0.162
ENSG00000174953 E013 19.7301055 0.0023760919 8.919321e-02 3.100178e-01 3 154280763 154280862 100 - 1.357 1.240 -0.408
ENSG00000174953 E014 20.8012110 0.0006656750 8.799582e-01 9.595325e-01 3 154283188 154283271 84 - 1.329 1.339 0.037
ENSG00000174953 E015 14.3570331 0.0009846355 9.452909e-01 9.850898e-01 3 154284583 154284652 70 - 1.179 1.184 0.021
ENSG00000174953 E016 8.2585875 0.0071292998 5.632894e-01 8.026964e-01 3 154284653 154284669 17 - 0.985 0.927 -0.217
ENSG00000174953 E017 0.1187032 0.0117743624 8.024692e-01   3 154284781 154284813 33 - 0.080 0.000 -7.974
ENSG00000174953 E018 24.1427820 0.0014850342 2.928458e-01 5.864358e-01 3 154284814 154284987 174 - 1.421 1.357 -0.222
ENSG00000174953 E019 18.0172735 0.0013193384 6.117818e-02 2.483878e-01 3 154288866 154288964 99 - 1.325 1.193 -0.464
ENSG00000174953 E020 20.8737938 0.0006671302 4.870036e-01 7.506731e-01 3 154289709 154289826 118 - 1.353 1.309 -0.154
ENSG00000174953 E021 22.5128665 0.0008456080 8.442677e-01 9.444102e-01 3 154292551 154292694 144 - 1.360 1.373 0.045
ENSG00000174953 E022 11.5172980 0.0012216764 3.607473e-01 6.503794e-01 3 154293748 154293812 65 - 1.123 1.046 -0.278
ENSG00000174953 E023 8.5362748 0.0017529835 5.097284e-01 7.674956e-01 3 154295284 154295297 14 - 0.947 1.010 0.234
ENSG00000174953 E024 12.8748397 0.0084222335 7.369639e-01 8.957127e-01 3 154295298 154295339 42 - 1.149 1.121 -0.099
ENSG00000174953 E025 18.6791174 0.0014081437 3.973035e-01 6.814751e-01 3 154299838 154299925 88 - 1.312 1.255 -0.201
ENSG00000174953 E026 18.3834341 0.0024439602 9.187753e-02 3.148036e-01 3 154300594 154300696 103 - 1.329 1.209 -0.420
ENSG00000174953 E027 19.8182951 0.0108352875 9.511865e-01 9.876839e-01 3 154300987 154301127 141 - 1.312 1.315 0.010
ENSG00000174953 E028 5.5900155 0.0662599642 8.245732e-01 9.363624e-01 3 154303329 154303343 15 - 0.808 0.823 0.060
ENSG00000174953 E029 11.2187049 0.0303837920 4.711757e-01 7.386409e-01 3 154303344 154303410 67 - 1.052 1.121 0.251
ENSG00000174953 E030 19.0488793 0.0094729027 5.269598e-01 7.790858e-01 3 154304806 154304972 167 - 1.316 1.269 -0.167
ENSG00000174953 E031 9.7069771 0.0014760061 6.011209e-01 8.254832e-01 3 154305094 154305168 75 - 1.044 0.997 -0.171
ENSG00000174953 E032 0.0000000       3 154305169 154305337 169 -      
ENSG00000174953 E033 9.1899039 0.0016402077 1.812776e-01 4.571054e-01 3 154306216 154306295 80 - 1.052 0.927 -0.463
ENSG00000174953 E034 12.0779224 0.0025760862 8.893980e-02 3.094561e-01 3 154309653 154309795 143 - 1.167 1.022 -0.522
ENSG00000174953 E035 4.2369671 0.0033427131 4.626122e-01 7.329899e-01 3 154309796 154309823 28 - 0.750 0.660 -0.373
ENSG00000174953 E036 4.4991072 0.0031714438 9.844493e-01 9.987925e-01 3 154311636 154311674 39 - 0.735 0.738 0.013
ENSG00000174953 E037 1.2440482 0.0158369017 6.318850e-02 2.528599e-01 3 154311675 154312248 574 - 0.205 0.489 1.788
ENSG00000174953 E038 0.8701572 0.0131459989 9.979581e-02 3.300256e-01 3 154314651 154315045 395 - 0.147 0.396 1.887
ENSG00000174953 E039 17.6731811 0.0011284500 1.289125e-01 3.808901e-01 3 154315046 154315280 235 - 1.308 1.201 -0.376
ENSG00000174953 E040 11.2250714 0.0097786210 9.382908e-02 3.185357e-01 3 154316039 154316163 125 - 1.142 0.984 -0.576
ENSG00000174953 E041 0.0000000       3 154319081 154319284 204 -      
ENSG00000174953 E042 4.6134399 0.0058706575 9.129930e-01 9.723616e-01 3 154324174 154324487 314 - 0.750 0.738 -0.051

Help

Please Click HERE to learn more details about the results from DEXseq.