ENSG00000174996

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000316924 ENSG00000174996 No_inf pgKDN_inf KLC2 protein_coding protein_coding 13.15018 11.00615 12.64252 0.7126367 0.4732667 0.1998049 2.5026861 0.0000000 5.4031050 0.0000000 2.8360492 9.0803126 0.19281667 0.000000 0.45450 0.454500 0.14772209 0.02746665 FALSE TRUE
ENST00000394065 ENSG00000174996 No_inf pgKDN_inf KLC2 protein_coding protein_coding 13.15018 11.00615 12.64252 0.7126367 0.4732667 0.1998049 0.8280231 1.0076425 0.3353768 0.2220187 0.1515695 -1.5589879 0.06499167 0.091450 0.02615 -0.065300 0.45646659 0.02746665 FALSE TRUE
ENST00000394066 ENSG00000174996 No_inf pgKDN_inf KLC2 protein_coding protein_coding 13.15018 11.00615 12.64252 0.7126367 0.4732667 0.1998049 2.5350891 3.9885477 0.6135584 0.3914118 0.6135584 -2.6808795 0.19342500 0.363125 0.05125 -0.311875 0.02746665 0.02746665 FALSE TRUE
ENST00000394067 ENSG00000174996 No_inf pgKDN_inf KLC2 protein_coding protein_coding 13.15018 11.00615 12.64252 0.7126367 0.4732667 0.1998049 5.6865759 2.9794959 5.7003916 0.9942689 3.3015313 0.9336875 0.41810833 0.266875 0.42360 0.156725 0.99782576 0.02746665 FALSE TRUE
ENST00000421552 ENSG00000174996 No_inf pgKDN_inf KLC2 protein_coding protein_coding 13.15018 11.00615 12.64252 0.7126367 0.4732667 0.1998049 0.2355562 0.7066687 0.0000000 0.7066687 0.0000000 -6.1632345 0.02357500 0.070725 0.00000 -0.070725 0.84455002 0.02746665 FALSE TRUE
ENST00000483152 ENSG00000174996 No_inf pgKDN_inf KLC2 protein_coding retained_intron 13.15018 11.00615 12.64252 0.7126367 0.4732667 0.1998049 0.3614711 0.6308180 0.0000000 0.2388602 0.0000000 -6.0018427 0.02809167 0.059400 0.00000 -0.059400 0.16108569 0.02746665 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000174996 E001 0.0000000       11 66257294 66257488 195 +      
ENSG00000174996 E002 0.5003641 0.0220458092 0.243837686 0.53388504 11 66257620 66257702 83 + 0.087 0.257 1.864
ENSG00000174996 E003 0.6275005 0.0307128769 0.124122094 0.37325905 11 66257703 66257718 16 + 0.087 0.318 2.279
ENSG00000174996 E004 0.8733399 0.2402497393 0.255327838 0.54724553 11 66257719 66257730 12 + 0.160 0.371 1.600
ENSG00000174996 E005 1.5875370 0.0088651788 0.970464576 0.99411286 11 66257731 66257789 59 + 0.408 0.418 0.056
ENSG00000174996 E006 1.9431040 0.0071690454 0.514356789 0.77103210 11 66257790 66257807 18 + 0.508 0.418 -0.458
ENSG00000174996 E007 2.5364246 0.0076172554 0.113973690 0.35554371 11 66257808 66257871 64 + 0.637 0.418 -1.043
ENSG00000174996 E008 1.2258918 0.0179866581 0.782134219 0.91618702 11 66258036 66258544 509 + 0.325 0.371 0.278
ENSG00000174996 E009 0.0000000       11 66258545 66258546 2 +      
ENSG00000174996 E010 0.8426232 0.0127573672 0.358147891 0.64765696 11 66258547 66258583 37 + 0.325 0.187 -1.043
ENSG00000174996 E011 7.4485024 0.0098421243 0.840072035 0.94258822 11 66258584 66258822 239 + 0.932 0.918 -0.054
ENSG00000174996 E012 2.2492415 0.0063185887 0.005704937 0.05442952 11 66260913 66261741 829 + 0.276 0.679 2.086
ENSG00000174996 E013 0.0000000       11 66261742 66261835 94 +      
ENSG00000174996 E014 3.6388064 0.0215603964 0.349033727 0.63954188 11 66261836 66261929 94 + 0.718 0.598 -0.510
ENSG00000174996 E015 4.2643188 0.0033864873 0.740813119 0.89714860 11 66261930 66261972 43 + 0.736 0.703 -0.136
ENSG00000174996 E016 4.9973715 0.0029886525 0.823858172 0.93607999 11 66262123 66262192 70 + 0.786 0.767 -0.075
ENSG00000174996 E017 0.6347396 0.0154843349 0.012238521 0.09156460 11 66262193 66262655 463 + 0.000 0.371 12.046
ENSG00000174996 E018 6.1050634 0.0028149295 0.957409355 0.98981997 11 66262814 66262917 104 + 0.845 0.857 0.047
ENSG00000174996 E019 6.2764427 0.0345124700 0.176463132 0.45063270 11 66262918 66263036 119 + 0.770 0.945 0.677
ENSG00000174996 E020 0.0000000       11 66263037 66263062 26 +      
ENSG00000174996 E021 5.3534941 0.0027324686 0.526044117 0.77860708 11 66263660 66263747 88 + 0.831 0.767 -0.252
ENSG00000174996 E022 8.9386791 0.0017270387 0.009954735 0.08001590 11 66263851 66263952 102 + 1.091 0.857 -0.870
ENSG00000174996 E023 19.3475489 0.0007706076 0.275440664 0.56900169 11 66264046 66264219 174 + 1.336 1.274 -0.216
ENSG00000174996 E024 12.1009112 0.0011241038 0.709211310 0.88230579 11 66264345 66264444 100 + 1.099 1.136 0.133
ENSG00000174996 E025 3.6838603 0.0045138520 0.402778394 0.68582320 11 66265023 66265072 50 + 0.614 0.725 0.471
ENSG00000174996 E026 0.0000000       11 66265168 66265235 68 +      
ENSG00000174996 E027 6.0645192 0.0035981221 0.170642941 0.44294236 11 66265655 66265763 109 + 0.909 0.767 -0.552
ENSG00000174996 E028 12.5519296 0.0012660965 0.543909571 0.79061953 11 66265854 66266012 159 + 1.150 1.109 -0.145
ENSG00000174996 E029 12.4109402 0.0011340564 0.354354048 0.64415060 11 66266093 66266217 125 + 1.156 1.091 -0.236
ENSG00000174996 E030 8.8200132 0.0019002173 0.454008291 0.72669719 11 66266433 66266490 58 + 0.954 1.030 0.279
ENSG00000174996 E031 1.4976586 0.0117861759 0.041434068 0.19770525 11 66266491 66266872 382 + 0.222 0.535 1.864
ENSG00000174996 E032 24.5456709 0.0006698286 0.849268249 0.94642935 11 66266873 66267173 301 + 1.398 1.416 0.063
ENSG00000174996 E033 4.3073083 0.0034981045 0.174770678 0.44858334 11 66267174 66267188 15 + 0.637 0.806 0.694
ENSG00000174996 E034 29.1394449 0.0187580733 0.479432803 0.74518682 11 66267189 66267860 672 + 1.449 1.509 0.206

Help

Please Click HERE to learn more details about the results from DEXseq.