ENSG00000175221

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000325464 ENSG00000175221 No_inf pgKDN_inf MED16 protein_coding protein_coding 15.76929 14.18117 15.88304 1.140287 0.9064631 0.1634018 0.5863767 0.000000 1.1206166 0.0000000 1.1206166 6.820966 0.03590000 0.000000 0.070475 0.070475 0.8502636057 0.0001315977 FALSE TRUE
ENST00000395808 ENSG00000175221 No_inf pgKDN_inf MED16 protein_coding protein_coding 15.76929 14.18117 15.88304 1.140287 0.9064631 0.1634018 2.3104197 5.256368 0.2535287 0.8229698 0.1466516 -4.320776 0.16225000 0.390500 0.015500 -0.375000 0.0001315977 0.0001315977 FALSE TRUE
ENST00000607471 ENSG00000175221 No_inf pgKDN_inf MED16 protein_coding protein_coding 15.76929 14.18117 15.88304 1.140287 0.9064631 0.1634018 1.2256699 1.631361 0.5016232 1.0160555 0.5016232 -1.681739 0.07732500 0.111825 0.033825 -0.078000 0.8061120404 0.0001315977 FALSE TRUE
ENST00000621073 ENSG00000175221 No_inf pgKDN_inf MED16 protein_coding protein_coding 15.76929 14.18117 15.88304 1.140287 0.9064631 0.1634018 0.8886054 1.806101 0.8597153 1.1094440 0.8597153 -1.062229 0.05284167 0.111875 0.046650 -0.065225 0.8097422148 0.0001315977 FALSE TRUE
MSTRG.14157.4 ENSG00000175221 No_inf pgKDN_inf MED16 protein_coding   15.76929 14.18117 15.88304 1.140287 0.9064631 0.1634018 6.0815328 4.011947 6.2930629 1.4404204 1.5266288 0.648159 0.38920833 0.294550 0.407000 0.112450 0.8427252287 0.0001315977 FALSE TRUE
MSTRG.14157.9 ENSG00000175221 No_inf pgKDN_inf MED16 protein_coding   15.76929 14.18117 15.88304 1.140287 0.9064631 0.1634018 4.6370875 1.408924 6.8544979 1.4089238 1.8736045 2.274357 0.28013333 0.087100 0.426550 0.339450 0.0539882716 0.0001315977 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000175221 E001 0.0000000       19 867630 867852 223 -      
ENSG00000175221 E002 0.0000000       19 867853 867876 24 -      
ENSG00000175221 E003 0.0000000       19 867877 867903 27 -      
ENSG00000175221 E004 0.8788159 0.0158669153 0.04613985 0.21069397 19 867904 867962 59 - 0.093 0.397 2.640
ENSG00000175221 E005 1.0060782 0.0141854972 0.02416269 0.14239408 19 867963 867963 1 - 0.093 0.439 2.862
ENSG00000175221 E006 1.1329322 0.0152765593 0.01286253 0.09460356 19 867964 867967 4 - 0.093 0.476 3.055
ENSG00000175221 E007 18.5616482 0.0008725861 0.11004425 0.34810185 19 867968 868251 284 - 1.233 1.342 0.381
ENSG00000175221 E008 19.7035246 0.0007582776 0.96471401 0.99255804 19 868252 868410 159 - 1.316 1.316 0.001
ENSG00000175221 E009 8.7435897 0.0018646412 0.07780821 0.28543792 19 868411 868415 5 - 1.063 0.902 -0.597
ENSG00000175221 E010 15.9779268 0.0085240054 0.37716344 0.66417290 19 868416 868499 84 - 1.262 1.196 -0.232
ENSG00000175221 E011 14.5956773 0.0039515588 0.54326467 0.79019516 19 868863 868946 84 - 1.167 1.217 0.176
ENSG00000175221 E012 23.4024454 0.0005978550 0.77069520 0.91150772 19 871037 871253 217 - 1.377 1.397 0.070
ENSG00000175221 E013 0.0000000       19 871606 871662 57 -      
ENSG00000175221 E014 21.6892670 0.0038793287 0.09079093 0.31294931 19 871926 872118 193 - 1.407 1.300 -0.370
ENSG00000175221 E015 0.1272623 0.0123069848 0.52212446   19 872913 873009 97 - 0.000 0.097 8.901
ENSG00000175221 E016 13.6972024 0.0012920982 0.82803525 0.93773864 19 873449 873535 87 - 1.174 1.160 -0.048
ENSG00000175221 E017 8.8076571 0.0202591938 0.93676242 0.98195648 19 873536 873582 47 - 0.995 0.988 -0.026
ENSG00000175221 E018 8.5536326 0.0072183455 0.57900319 0.81187495 19 875244 875331 88 - 1.005 0.953 -0.193
ENSG00000175221 E019 10.9077964 0.0044312560 0.65106720 0.85302431 19 875332 875454 123 - 1.054 1.096 0.152
ENSG00000175221 E020 15.8771511 0.0212254675 0.17294137 0.44588943 19 876974 877180 207 - 1.160 1.283 0.437
ENSG00000175221 E021 16.2630520 0.0144332580 0.10160927 0.33285841 19 879937 880148 212 - 1.160 1.300 0.495
ENSG00000175221 E022 14.9279089 0.0009416155 0.84512185 0.94490574 19 881559 881714 156 - 1.208 1.196 -0.040
ENSG00000175221 E023 12.3644918 0.0011751114 0.95672505 0.98975055 19 884903 885008 106 - 1.122 1.129 0.026
ENSG00000175221 E024 9.5335741 0.0015329014 0.75010119 0.90145751 19 885770 885821 52 - 1.035 1.010 -0.093
ENSG00000175221 E025 23.3709766 0.0005958192 0.87686186 0.95824250 19 885822 886201 380 - 1.390 1.384 -0.021
ENSG00000175221 E026 9.8036272 0.0014609574 0.71821200 0.88658715 19 889638 889807 170 - 1.016 1.050 0.127
ENSG00000175221 E027 9.7869351 0.0017598656 0.93037165 0.97965023 19 890137 890244 108 - 1.035 1.031 -0.017
ENSG00000175221 E028 0.0000000       19 890245 890423 179 -      
ENSG00000175221 E029 5.8017111 0.0025290274 0.01195115 0.09023785 19 890963 890983 21 - 0.951 0.676 -1.083
ENSG00000175221 E030 15.3758688 0.0008890350 0.36284512 0.65192034 19 890984 891149 166 - 1.245 1.182 -0.221
ENSG00000175221 E031 0.2448930 0.0160463706 0.98136663   19 892347 893085 739 - 0.093 0.097 0.055
ENSG00000175221 E032 3.3986634 0.0042853687 0.29477958 0.58801102 19 893086 893218 133 - 0.706 0.573 -0.573

Help

Please Click HERE to learn more details about the results from DEXseq.