ENSG00000175274

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000395648 ENSG00000175274 No_inf pgKDN_inf TP53I11 protein_coding protein_coding 24.64236 49.43818 16.16134 0.8277409 0.3646851 -1.612478 14.1689445 30.1526981 8.2992294 2.4983694 2.8655339 -1.8599789 0.53398333 0.607950 0.508025 -0.099925 0.90499972 0.01706337 FALSE  
ENST00000524774 ENSG00000175274 No_inf pgKDN_inf TP53I11 protein_coding retained_intron 24.64236 49.43818 16.16134 0.8277409 0.3646851 -1.612478 1.9888387 5.0220301 0.1744259 0.3711934 0.1744259 -4.7700275 0.06655000 0.102000 0.011275 -0.090725 0.02023715 0.01706337    
ENST00000532253 ENSG00000175274 No_inf pgKDN_inf TP53I11 protein_coding nonsense_mediated_decay 24.64236 49.43818 16.16134 0.8277409 0.3646851 -1.612478 0.6238709 0.0000000 1.4456936 0.0000000 0.8091580 7.1855630 0.04863333 0.000000 0.089050 0.089050 0.01706337 0.01706337 FALSE  
MSTRG.4679.2 ENSG00000175274 No_inf pgKDN_inf TP53I11 protein_coding   24.64236 49.43818 16.16134 0.8277409 0.3646851 -1.612478 1.6703196 3.8817020 1.1292569 1.6770616 1.1292569 -1.7723081 0.05106667 0.080225 0.072975 -0.007250 0.55433945 0.01706337 FALSE  
MSTRG.4679.7 ENSG00000175274 No_inf pgKDN_inf TP53I11 protein_coding   24.64236 49.43818 16.16134 0.8277409 0.3646851 -1.612478 1.0301300 0.9230819 1.6893396 0.6068978 0.7637251 0.8648986 0.05742500 0.018350 0.101525 0.083175 0.49692522 0.01706337 FALSE  
MSTRG.4679.9 ENSG00000175274 No_inf pgKDN_inf TP53I11 protein_coding   24.64236 49.43818 16.16134 0.8277409 0.3646851 -1.612478 1.4324411 0.0000000 2.2691399 0.0000000 2.2691399 7.8323457 0.13226667 0.000000 0.146625 0.146625 0.75295675 0.01706337 FALSE  
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000175274 E001 0.0000000       11 44885903 44886564 662 -      
ENSG00000175274 E002 0.0000000       11 44901220 44901318 99 -      
ENSG00000175274 E003 0.0000000       11 44903356 44903659 304 -      
ENSG00000175274 E004 0.0000000       11 44903780 44903890 111 -      
ENSG00000175274 E005 0.0000000       11 44932348 44932352 5 -      
ENSG00000175274 E006 0.0000000       11 44932353 44932355 3 -      
ENSG00000175274 E007 0.0000000       11 44932356 44932360 5 -      
ENSG00000175274 E008 169.0956465 0.0002093281 1.303550e-03 0.018366164 11 44932361 44933482 1122 - 2.108 2.188 0.267
ENSG00000175274 E009 235.7389873 0.0001087873 2.454219e-01 0.535955134 11 44933483 44934947 1465 - 2.295 2.318 0.079
ENSG00000175274 E010 14.2910186 0.0009971432 4.445596e-01 0.719103729 11 44934948 44934979 32 - 1.172 1.111 -0.220
ENSG00000175274 E011 15.6628305 0.0009638379 4.527825e-01 0.725749982 11 44934980 44935017 38 - 1.206 1.148 -0.206
ENSG00000175274 E012 10.4248684 0.0101810597 3.841753e-01 0.670293406 11 44935561 44935567 7 - 1.064 0.979 -0.315
ENSG00000175274 E013 11.4102664 0.0072737584 2.996295e-01 0.592498440 11 44935568 44935577 10 - 1.108 1.011 -0.353
ENSG00000175274 E014 13.7890409 0.0012352811 4.306821e-01 0.708528734 11 44935578 44935619 42 - 1.160 1.096 -0.232
ENSG00000175274 E015 15.5148526 0.0009040588 2.294091e-01 0.518043516 11 44935620 44935662 43 - 1.228 1.135 -0.332
ENSG00000175274 E016 4.8147647 0.0029440146 6.697957e-05 0.001692026 11 44935663 44936056 394 - 0.149 0.809 3.737
ENSG00000175274 E017 4.9165616 0.0028308687 1.254246e-02 0.093036056 11 44936218 44936455 238 - 0.420 0.788 1.657
ENSG00000175274 E018 4.1516364 0.0040025002 4.581250e-02 0.209678475 11 44936456 44936558 103 - 0.420 0.721 1.385
ENSG00000175274 E019 4.9223871 0.0028306088 3.004913e-03 0.034540819 11 44936559 44936667 109 - 0.347 0.799 2.112
ENSG00000175274 E020 2.1393225 0.0065681002 1.409290e-01 0.399351818 11 44936668 44936689 22 - 0.259 0.506 1.434
ENSG00000175274 E021 1.2584959 0.0141693437 2.056542e-01 0.489015026 11 44936690 44936802 113 - 0.149 0.366 1.697
ENSG00000175274 E022 10.3203910 0.0013083721 6.055245e-01 0.828055781 11 44936803 44936803 1 - 1.033 0.985 -0.175
ENSG00000175274 E023 13.9011974 0.0009986860 2.514921e-01 0.542602301 11 44936804 44936842 39 - 1.184 1.090 -0.335
ENSG00000175274 E024 10.0237877 0.0014213062 6.355452e-02 0.253676657 11 44936843 44936849 7 - 1.108 0.937 -0.630
ENSG00000175274 E025 9.0451575 0.0015542615 1.399278e-01 0.397875548 11 44936850 44936856 7 - 1.049 0.906 -0.532
ENSG00000175274 E026 10.4137012 0.0015746384 1.605366e-01 0.428378241 11 44936857 44936879 23 - 1.094 0.965 -0.473
ENSG00000175274 E027 7.4186608 0.0022246838 8.330534e-02 0.297474349 11 44936880 44936882 3 - 0.999 0.818 -0.684
ENSG00000175274 E028 8.5155562 0.0085673472 2.850130e-02 0.158085116 11 44936883 44936899 17 - 1.080 0.856 -0.835
ENSG00000175274 E029 0.5082940 0.2235348488 4.029078e-01 0.685956973 11 44936900 44937108 209 - 0.000 0.201 10.411
ENSG00000175274 E030 0.6268712 0.0150974612 7.879083e-01 0.918663609 11 44937109 44937303 195 - 0.149 0.201 0.527
ENSG00000175274 E031 7.7872947 0.0105676023 5.487726e-02 0.233326679 11 44937304 44937320 17 - 1.033 0.828 -0.772
ENSG00000175274 E032 8.5467488 0.0019454728 1.267236e-01 0.377358229 11 44937321 44937352 32 - 1.033 0.881 -0.566
ENSG00000175274 E033 12.1719622 0.0013836937 3.525315e-01 0.642562898 11 44937555 44937613 59 - 1.122 1.041 -0.292
ENSG00000175274 E034 20.7473696 0.0012879406 3.074343e-01 0.600616630 11 44938207 44938366 160 - 1.330 1.260 -0.246
ENSG00000175274 E035 0.1272623 0.0122908872 1.000000e+00   11 44938367 44938417 51 - 0.000 0.060 9.380
ENSG00000175274 E036 0.8715465 0.0274115095 8.965040e-01 0.965963091 11 44939114 44939165 52 - 0.259 0.239 -0.151
ENSG00000175274 E037 2.7193661 0.0056474617 3.100415e-01 0.603325779 11 44939166 44939190 25 - 0.630 0.485 -0.665
ENSG00000175274 E038 2.8289110 0.0094256824 8.339526e-02 0.297593381 11 44939191 44939281 91 - 0.706 0.464 -1.094
ENSG00000175274 E039 0.9993085 0.0126999092 9.306882e-01 0.979806458 11 44940514 44940747 234 - 0.259 0.275 0.112
ENSG00000175274 E040 1.2222391 0.0103455656 1.161243e-01 0.359284664 11 44941003 44941077 75 - 0.483 0.239 -1.473
ENSG00000175274 E041 0.3798680 0.0341181739 5.167936e-01   11 44943152 44943191 40 - 0.000 0.159 10.800
ENSG00000175274 E042 0.1268540 0.0122639712 1.000000e+00   11 44947039 44947253 215 - 0.000 0.060 9.380
ENSG00000175274 E043 0.4911106 0.0161770168 3.139610e-01   11 44949973 44950208 236 - 0.259 0.112 -1.473
ENSG00000175274 E044 9.9726844 0.0098813016 7.895725e-01 0.919241993 11 44950677 44950876 200 - 0.962 0.992 0.112
ENSG00000175274 E045 0.7620020 0.0292278836 1.440105e-01 0.404092651 11 44950877 44951306 430 - 0.000 0.275 11.788

Help

Please Click HERE to learn more details about the results from DEXseq.