ENSG00000175348

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000309134 ENSG00000175348 No_inf pgKDN_inf TMEM9B protein_coding protein_coding 54.02176 47.87501 59.86148 0.989054 1.417165 0.3222948 16.13033 21.348197 12.25875 0.8828234 5.005980 -0.7998014 0.3088250 0.446775 0.205400 -0.241375 0.46762833 0.03676324 FALSE FALSE
ENST00000525069 ENSG00000175348 No_inf pgKDN_inf TMEM9B protein_coding protein_coding 54.02176 47.87501 59.86148 0.989054 1.417165 0.3222948 11.57798 8.412717 12.75875 0.8205284 1.714928 0.6002593 0.2125833 0.175875 0.213875 0.038000 0.84292705 0.03676324 FALSE TRUE
ENST00000534025 ENSG00000175348 No_inf pgKDN_inf TMEM9B protein_coding protein_coding 54.02176 47.87501 59.86148 0.989054 1.417165 0.3222948 25.34720 15.996510 34.52000 0.9720145 3.885724 1.1091917 0.4593417 0.333325 0.575300 0.241975 0.03676324 0.03676324 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000175348 E001 0.2539903 0.0160782225 0.195755729   11 8947141 8947201 61 - 0.000 0.185 10.456
ENSG00000175348 E002 1.0888070 0.0107986189 0.434535214 0.71177489 11 8947202 8947293 92 - 0.371 0.255 -0.756
ENSG00000175348 E003 32.7990394 0.0004686177 0.264036447 0.55712061 11 8947294 8947500 207 - 1.496 1.561 0.222
ENSG00000175348 E004 291.8844393 0.0040028079 0.199613782 0.48132130 11 8947501 8948475 975 - 2.451 2.482 0.104
ENSG00000175348 E005 1.3540631 0.0095111743 0.588295473 0.81727656 11 8952692 8953202 511 - 0.327 0.415 0.507
ENSG00000175348 E006 39.0182822 0.0004366024 0.485301898 0.74916345 11 8953203 8953261 59 - 1.613 1.589 -0.082
ENSG00000175348 E007 44.7701907 0.0013292322 0.362793988 0.65192034 11 8953262 8953337 76 - 1.636 1.685 0.165
ENSG00000175348 E008 47.8122523 0.0013670106 0.526071628 0.77860979 11 8956190 8956298 109 - 1.697 1.678 -0.066
ENSG00000175348 E009 0.1268540 0.0123725486 0.463745199   11 8959313 8959367 55 - 0.000 0.103 11.300
ENSG00000175348 E010 23.4774963 0.0065992429 0.003244031 0.03661049 11 8962092 8962183 92 - 1.471 1.275 -0.679
ENSG00000175348 E011 0.0000000       11 8962695 8962852 158 -      
ENSG00000175348 E012 0.2363338 0.0157624996 0.297405601   11 8963991 8964208 218 - 0.161 0.000 -12.707
ENSG00000175348 E013 29.0623990 0.0004574894 0.071728156 0.27149880 11 8964209 8964442 234 - 1.518 1.429 -0.306
ENSG00000175348 E014 0.0000000       11 8964890 8965011 122 -      

Help

Please Click HERE to learn more details about the results from DEXseq.