ENSG00000175581

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000310614 ENSG00000175581 No_inf pgKDN_inf MRPL48 protein_coding protein_coding 10.85716 8.204052 9.767813 0.332086 0.2872414 0.2514178 6.5786890 7.4230579 5.9256160 0.2878644 0.7920331 -0.3245581 0.65767500 0.906825 0.602550 -0.304275 0.04668131 0.04668131 FALSE TRUE
ENST00000497094 ENSG00000175581 No_inf pgKDN_inf MRPL48 protein_coding protein_coding 10.85716 8.204052 9.767813 0.332086 0.2872414 0.2514178 1.2423664 0.0000000 0.3279616 0.0000000 0.3279616 5.0787875 0.07842500 0.000000 0.031425 0.031425 0.84609057 0.04668131 FALSE FALSE
ENST00000508278 ENSG00000175581 No_inf pgKDN_inf MRPL48 protein_coding nonsense_mediated_decay 10.85716 8.204052 9.767813 0.332086 0.2872414 0.2514178 0.4274831 0.1540412 0.8884364 0.1540412 0.6109473 2.4533585 0.04461667 0.017100 0.095600 0.078500 0.82150607 0.04668131 FALSE TRUE
ENST00000535277 ENSG00000175581 No_inf pgKDN_inf MRPL48 protein_coding protein_coding 10.85716 8.204052 9.767813 0.332086 0.2872414 0.2514178 0.2587991 0.0000000 0.7763973 0.0000000 0.4591256 6.2971865 0.02664167 0.000000 0.079925 0.079925 0.51498070 0.04668131   FALSE
ENST00000540162 ENSG00000175581 No_inf pgKDN_inf MRPL48 protein_coding nonsense_mediated_decay 10.85716 8.204052 9.767813 0.332086 0.2872414 0.2514178 0.9142254 0.2893596 1.4464790 0.1715348 0.6086153 2.2825334 0.08490000 0.036550 0.150350 0.113800 0.60800511 0.04668131 FALSE TRUE
ENST00000543374 ENSG00000175581 No_inf pgKDN_inf MRPL48 protein_coding retained_intron 10.85716 8.204052 9.767813 0.332086 0.2872414 0.2514178 1.0730948 0.0000000 0.0000000 0.0000000 0.0000000 0.0000000 0.07486667 0.000000 0.000000 0.000000   0.04668131 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000175581 E001 0.0000000       11 73787872 73787873 2 +      
ENSG00000175581 E002 0.0000000       11 73787874 73787876 3 +      
ENSG00000175581 E003 0.0000000       11 73787877 73787882 6 +      
ENSG00000175581 E004 0.0000000       11 73787883 73787884 2 +      
ENSG00000175581 E005 0.0000000       11 73787885 73787890 6 +      
ENSG00000175581 E006 0.4811342 0.017335608 0.303979607   11 73787891 73787894 4 + 0.242 0.094 -1.627
ENSG00000175581 E007 0.6076412 0.016188641 0.629936531 0.84125679 11 73787895 73787905 11 + 0.242 0.171 -0.627
ENSG00000175581 E008 1.4595763 0.009984365 0.524727922 0.77774749 11 73787906 73787908 3 + 0.437 0.344 -0.527
ENSG00000175581 E009 2.7103267 0.010413421 0.444064005 0.71872725 11 73787909 73787929 21 + 0.510 0.617 0.489
ENSG00000175581 E010 4.7962401 0.003978035 0.487513075 0.75091417 11 73787930 73787956 27 + 0.718 0.800 0.330
ENSG00000175581 E011 5.8925686 0.007491454 0.656353035 0.85614544 11 73787957 73787992 36 + 0.810 0.862 0.199
ENSG00000175581 E012 0.3532727 0.016502246 0.096547990   11 73789335 73789490 156 + 0.242 0.000 -11.705
ENSG00000175581 E013 0.0000000       11 73802081 73802177 97 +      
ENSG00000175581 E014 5.0230775 0.002967840 0.965310720 0.99272752 11 73805027 73805079 53 + 0.776 0.783 0.029
ENSG00000175581 E015 0.0000000       11 73808308 73808312 5 +      
ENSG00000175581 E016 3.9452229 0.003589630 0.329347569 0.62172843 11 73808313 73808350 38 + 0.626 0.747 0.506
ENSG00000175581 E017 0.9622323 0.018524989 0.140195565 0.39840390 11 73817823 73817947 125 + 0.396 0.171 -1.627
ENSG00000175581 E018 0.3635961 0.017044578 0.562236315   11 73823013 73823070 58 + 0.175 0.094 -1.042
ENSG00000175581 E019 7.8711278 0.002808832 0.530595235 0.78163231 11 73825708 73825796 89 + 0.914 0.975 0.230
ENSG00000175581 E020 0.6359033 0.245858681 0.061928505 0.25002526 11 73842113 73843246 1134 + 0.000 0.344 12.253
ENSG00000175581 E021 0.3727544 0.016679293 0.604180986   11 73843247 73843367 121 + 0.096 0.171 0.958
ENSG00000175581 E022 16.6580548 0.000907294 0.006038744 0.05677072 11 73844807 73844976 170 + 1.330 1.154 -0.618
ENSG00000175581 E023 0.0000000       11 73844977 73845137 161 +      
ENSG00000175581 E024 13.5468138 0.001072809 0.149813476 0.41226797 11 73859907 73860009 103 + 1.103 1.209 0.381
ENSG00000175581 E025 0.0000000       11 73860010 73860480 471 +      
ENSG00000175581 E026 10.1613006 0.001495471 0.780494129 0.91537109 11 73863172 73863261 90 + 1.058 1.037 -0.076
ENSG00000175581 E027 16.2019341 0.013461634 0.742077127 0.89791856 11 73864296 73865133 838 + 1.221 1.247 0.089

Help

Please Click HERE to learn more details about the results from DEXseq.