ENSG00000175787

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000340911 ENSG00000175787 No_inf pgKDN_inf ZNF169 protein_coding protein_coding 3.286059 2.094569 3.923615 0.1525415 0.1228234 0.9023309 0.4917739 0.3828399 0.5365526 0.38283987 0.2401322 0.476419 0.1452750 0.162925 0.134275 -0.028650 0.8462210124 0.0004080568 FALSE TRUE
ENST00000395395 ENSG00000175787 No_inf pgKDN_inf ZNF169 protein_coding protein_coding 3.286059 2.094569 3.923615 0.1525415 0.1228234 0.9023309 1.3794437 0.5741134 1.7995166 0.33291875 0.6673906 1.631284 0.3967917 0.266675 0.452650 0.185975 0.8305917179 0.0004080568 FALSE TRUE
ENST00000480716 ENSG00000175787 No_inf pgKDN_inf ZNF169 protein_coding protein_coding 3.286059 2.094569 3.923615 0.1525415 0.1228234 0.9023309 0.5377299 0.0000000 0.8654588 0.00000000 0.2204589 6.451967 0.1342250 0.000000 0.216200 0.216200 0.0778658468 0.0004080568 FALSE FALSE
ENST00000481550 ENSG00000175787 No_inf pgKDN_inf ZNF169 protein_coding protein_coding 3.286059 2.094569 3.923615 0.1525415 0.1228234 0.9023309 0.4184485 0.9526674 0.0000000 0.09914606 0.0000000 -6.588966 0.1823000 0.460825 0.000000 -0.460825 0.0004080568 0.0004080568 FALSE FALSE
MSTRG.28998.4 ENSG00000175787 No_inf pgKDN_inf ZNF169 protein_coding   3.286059 2.094569 3.923615 0.1525415 0.1228234 0.9023309 0.4586629 0.1849486 0.7220873 0.18494856 0.7220873 1.908922 0.1414167 0.109575 0.196900 0.087325 0.9866123192 0.0004080568 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000175787 E001 0.0000000       9 94259298 94259320 23 +      
ENSG00000175787 E002 0.0000000       9 94259321 94259327 7 +      
ENSG00000175787 E003 0.0000000       9 94259328 94259345 18 +      
ENSG00000175787 E004 0.4815440 0.018200081 0.6428244927   9 94278758 94278845 88 + 0.191 0.123 -0.757
ENSG00000175787 E005 0.9596246 0.013394342 0.4730385169 0.740157182 9 94292341 94292467 127 + 0.323 0.218 -0.757
ENSG00000175787 E006 0.0000000       9 94292468 94292623 156 +      
ENSG00000175787 E007 1.6696361 0.008228894 0.0571237535 0.238904507 9 94292974 94293069 96 + 0.506 0.218 -1.757
ENSG00000175787 E008 0.6345490 0.015973417 0.0036238040 0.039684517 9 94293070 94293441 372 + 0.000 0.420 12.764
ENSG00000175787 E009 10.9137808 0.002623831 0.0003630299 0.006796132 9 94293442 94295846 2405 + 0.940 1.213 0.990
ENSG00000175787 E010 1.3247991 0.012451535 0.4946439065 0.755960505 9 94299448 94299811 364 + 0.393 0.296 -0.587
ENSG00000175787 E011 0.1186381 0.012208750 1.0000000000   9 94299812 94299814 3 + 0.073 0.000 -10.339
ENSG00000175787 E012 22.3443432 0.001093595 0.0084015874 0.071483075 9 94299815 94301829 2015 + 1.389 1.292 -0.339

Help

Please Click HERE to learn more details about the results from DEXseq.