ENSG00000175792

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000322623 ENSG00000175792 No_inf pgKDN_inf RUVBL1 protein_coding protein_coding 22.7703 13.78356 27.1388 0.8946863 0.4688358 0.9768936 21.1230338 11.4400049 27.09806 0.3751064 0.4644963 1.243374 0.91591667 0.838000 0.9985 0.160500 6.138626e-07 6.138626e-07 FALSE TRUE
ENST00000472125 ENSG00000175792 No_inf pgKDN_inf RUVBL1 protein_coding protein_coding 22.7703 13.78356 27.1388 0.8946863 0.4688358 0.9768936 0.3567192 1.0701577 0.00000 1.0701577 0.0000000 -6.755098 0.02192500 0.065775 0.0000 -0.065775 8.050004e-01 6.138626e-07 FALSE TRUE
ENST00000480616 ENSG00000175792 No_inf pgKDN_inf RUVBL1 protein_coding protein_coding_CDS_not_defined 22.7703 13.78356 27.1388 0.8946863 0.4688358 0.9768936 0.2838910 0.8516731 0.00000 0.5084478 0.0000000 -6.429069 0.02134167 0.064025 0.0000 -0.064025 3.768463e-01 6.138626e-07   FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000175792 E001 0.0000000       3 128064778 128064781 4 -      
ENSG00000175792 E002 0.0000000       3 128064782 128064784 3 -      
ENSG00000175792 E003 0.0000000       3 128064785 128065220 436 -      
ENSG00000175792 E004 0.0000000       3 128068636 128068913 278 -      
ENSG00000175792 E005 0.1170040 0.0116792696 1.000000000   3 128080810 128080960 151 - 0.069 0.000 -10.503
ENSG00000175792 E006 14.6502322 0.0009834202 0.779605867 0.91504130 3 128080961 128081181 221 - 1.166 1.192 0.094
ENSG00000175792 E007 23.3444398 0.0108800950 0.817485048 0.93360879 3 128081182 128081409 228 - 1.370 1.359 -0.040
ENSG00000175792 E008 0.6159221 0.0164520115 0.230562074 0.51900564 3 128081410 128082482 1073 - 0.129 0.310 1.590
ENSG00000175792 E009 16.9903993 0.0019041301 0.186104914 0.46399534 3 128082483 128082574 92 - 1.266 1.172 -0.331
ENSG00000175792 E010 1.0058262 0.0844958383 0.003441078 0.03828199 3 128082575 128083601 1027 - 0.069 0.535 3.812
ENSG00000175792 E011 0.5078243 0.2125023409 0.017419142 0.11569603 3 128083602 128084075 474 - 0.000 0.378 14.407
ENSG00000175792 E012 0.2542726 0.1965280126 0.108391917   3 128084076 128084842 767 - 0.000 0.229 13.407
ENSG00000175792 E013 0.0000000       3 128084843 128085131 289 -      
ENSG00000175792 E014 22.6204522 0.0007307949 0.910738919 0.97174553 3 128087706 128087808 103 - 1.354 1.352 -0.007
ENSG00000175792 E015 0.0000000       3 128087809 128087844 36 -      
ENSG00000175792 E016 37.6177080 0.0003692468 0.868605414 0.95484273 3 128097300 128097498 199 - 1.567 1.565 -0.009
ENSG00000175792 E017 15.9795742 0.0011360508 0.744843141 0.89897204 3 128098882 128098945 64 - 1.200 1.229 0.102
ENSG00000175792 E018 25.3990665 0.0006817549 0.036104455 0.18242999 3 128100595 128100744 150 - 1.354 1.479 0.432
ENSG00000175792 E019 17.8626578 0.0007930261 0.122878379 0.37101625 3 128101559 128101648 90 - 1.214 1.325 0.387
ENSG00000175792 E020 21.6596909 0.0006703152 0.026060298 0.14928689 3 128104773 128104924 152 - 1.380 1.238 -0.496
ENSG00000175792 E021 19.1544865 0.0008121754 0.070074656 0.26789102 3 128112888 128113020 133 - 1.323 1.202 -0.427
ENSG00000175792 E022 13.6604846 0.0010560035 0.700969940 0.87819077 3 128119328 128119414 87 - 1.155 1.130 -0.092
ENSG00000175792 E023 14.7661842 0.0011724852 0.986105982 0.99919443 3 128123584 128123812 229 - 1.176 1.182 0.023
ENSG00000175792 E024 0.2537694 0.0164557806 0.082758446   3 128153203 128153914 712 - 0.000 0.229 13.407

Help

Please Click HERE to learn more details about the results from DEXseq.