ENSG00000176225

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000255674 ENSG00000176225 No_inf pgKDN_inf RTTN protein_coding protein_coding 3.825472 3.692904 3.764676 0.1852788 0.3113191 0.02769562 0.34336186 0.0000000 0.9826423 0.0000000 0.23558882 6.6332020 0.09554167 0.000000 0.276350 0.276350 0.0143159 0.0143159 FALSE TRUE
ENST00000579986 ENSG00000176225 No_inf pgKDN_inf RTTN protein_coding nonsense_mediated_decay 3.825472 3.692904 3.764676 0.1852788 0.3113191 0.02769562 0.89517797 0.9266079 1.0773023 0.3647870 0.36861829 0.2152360 0.23336667 0.239525 0.280700 0.041175 0.9920689 0.0143159 FALSE TRUE
ENST00000581161 ENSG00000176225 No_inf pgKDN_inf RTTN protein_coding nonsense_mediated_decay 3.825472 3.692904 3.764676 0.1852788 0.3113191 0.02769562 0.34864992 0.4113072 0.3289507 0.2130709 0.32895066 -0.3137974 0.09027500 0.111125 0.072550 -0.038575 0.8210889 0.0143159 FALSE TRUE
ENST00000581583 ENSG00000176225 No_inf pgKDN_inf RTTN protein_coding retained_intron 3.825472 3.692904 3.764676 0.1852788 0.3113191 0.02769562 0.08927361 0.2678208 0.0000000 0.2105256 0.00000000 -4.7960829 0.02375000 0.071250 0.000000 -0.071250 0.7032399 0.0143159 FALSE TRUE
ENST00000583043 ENSG00000176225 No_inf pgKDN_inf RTTN protein_coding nonsense_mediated_decay 3.825472 3.692904 3.764676 0.1852788 0.3113191 0.02769562 0.27968822 0.1297692 0.0000000 0.1297692 0.00000000 -3.8049748 0.07060833 0.040450 0.000000 -0.040450 0.8341082 0.0143159 TRUE TRUE
ENST00000638799 ENSG00000176225 No_inf pgKDN_inf RTTN protein_coding retained_intron 3.825472 3.692904 3.764676 0.1852788 0.3113191 0.02769562 0.77549886 0.9157954 0.3897475 0.1046800 0.03863539 -1.2116044 0.20202500 0.253450 0.103350 -0.150100 0.5317857 0.0143159 TRUE TRUE
ENST00000639128 ENSG00000176225 No_inf pgKDN_inf RTTN protein_coding retained_intron 3.825472 3.692904 3.764676 0.1852788 0.3113191 0.02769562 0.29494022 0.3799331 0.5048876 0.2703562 0.31040948 0.4010308 0.08140833 0.098650 0.145575 0.046925 0.9314955 0.0143159 TRUE TRUE
ENST00000677824 ENSG00000176225 No_inf pgKDN_inf RTTN protein_coding protein_coding 3.825472 3.692904 3.764676 0.1852788 0.3113191 0.02769562 0.24398030 0.2154217 0.1234141 0.2154217 0.12341409 -0.7567155 0.06355833 0.067150 0.038400 -0.028750 1.0000000 0.0143159 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000176225 E001 0.0000000       18 70003031 70003070 40 -      
ENSG00000176225 E002 0.2458395 0.016164807 0.872763831   18 70003071 70003803 733 - 0.087 0.103 0.270
ENSG00000176225 E003 0.0000000       18 70003804 70003804 1 -      
ENSG00000176225 E004 0.0000000       18 70003805 70003819 15 -      
ENSG00000176225 E005 0.0000000       18 70003820 70003829 10 -      
ENSG00000176225 E006 0.1186381 0.011854905 0.661835629   18 70003830 70003839 10 - 0.087 0.000 -11.599
ENSG00000176225 E007 0.1186381 0.011854905 0.661835629   18 70003840 70003858 19 - 0.087 0.000 -11.599
ENSG00000176225 E008 1.3342653 0.099439567 0.619465590 0.83540262 18 70003859 70003883 25 - 0.408 0.317 -0.538
ENSG00000176225 E009 1.8069329 0.016167176 0.155289561 0.42114885 18 70003884 70003968 85 - 0.538 0.317 -1.190
ENSG00000176225 E010 2.9493087 0.005521656 0.359694713 0.64919100 18 70003969 70004168 200 - 0.538 0.653 0.511
ENSG00000176225 E011 2.3310024 0.006617301 0.498593747 0.75899394 18 70004169 70004236 68 - 0.478 0.567 0.422
ENSG00000176225 E012 2.8148708 0.005518411 0.774798555 0.91349842 18 70005198 70005267 70 - 0.565 0.597 0.144
ENSG00000176225 E013 0.3817870 0.562453625 0.234806312   18 70005268 70006380 1113 - 0.000 0.257 13.620
ENSG00000176225 E014 2.1939797 0.006335063 0.972109792 0.99476602 18 70006381 70006474 94 - 0.509 0.498 -0.052
ENSG00000176225 E015 1.2043291 0.014201755 0.340285345 0.63190159 18 70006475 70006484 10 - 0.408 0.257 -0.952
ENSG00000176225 E016 0.2459655 0.016435229 0.872039202   18 70006485 70007066 582 - 0.087 0.103 0.270
ENSG00000176225 E017 0.9980837 0.011798757 0.085090834 0.30164907 18 70007376 70009032 1657 - 0.160 0.417 1.855
ENSG00000176225 E018 4.6164813 0.015232759 0.522520309 0.77595298 18 70017407 70017590 184 - 0.787 0.702 -0.347
ENSG00000176225 E019 1.7128414 0.008212046 0.701170930 0.87828330 18 70017591 70017643 53 - 0.408 0.460 0.270
ENSG00000176225 E020 1.3432057 0.009380827 0.968672148 0.99364123 18 70017644 70017672 29 - 0.369 0.370 0.007
ENSG00000176225 E021 1.3432057 0.009380827 0.968672148 0.99364123 18 70017673 70017674 2 - 0.369 0.370 0.007
ENSG00000176225 E022 0.0000000       18 70019290 70019501 212 -      
ENSG00000176225 E023 0.2438580 0.016436250 0.871432211   18 70019502 70019920 419 - 0.087 0.103 0.270
ENSG00000176225 E024 5.4757329 0.002975542 0.719124013 0.88680749 18 70020615 70020817 203 - 0.832 0.786 -0.182
ENSG00000176225 E025 0.0000000       18 70020818 70020845 28 -      
ENSG00000176225 E026 0.0000000       18 70020846 70021160 315 -      
ENSG00000176225 E027 0.0000000       18 70022204 70022248 45 -      
ENSG00000176225 E028 4.6578851 0.031576649 0.540100532 0.78826722 18 70024722 70024848 127 - 0.719 0.786 0.270
ENSG00000176225 E029 3.6705599 0.035567043 0.827888387 0.93773799 18 70028724 70028801 78 - 0.660 0.678 0.077
ENSG00000176225 E030 3.1982653 0.054778207 0.414111956 0.69445400 18 70030012 70030109 98 - 0.565 0.678 0.492
ENSG00000176225 E031 2.4690263 0.017716614 0.190547920 0.46976329 18 70030876 70030981 106 - 0.445 0.626 0.855
ENSG00000176225 E032 0.0000000       18 70031302 70031414 113 -      
ENSG00000176225 E033 4.5383838 0.006370381 0.431653300 0.70932601 18 70047971 70048188 218 - 0.700 0.786 0.348
ENSG00000176225 E034 2.4481602 0.008273594 0.651085744 0.85302431 18 70051411 70051548 138 - 0.509 0.567 0.270
ENSG00000176225 E035 0.0000000       18 70053295 70053514 220 -      
ENSG00000176225 E036 1.4621261 0.009383415 0.822948509 0.93562321 18 70054131 70054284 154 - 0.408 0.370 -0.215
ENSG00000176225 E037 0.1272623 0.012378925 0.435404656   18 70056319 70056387 69 - 0.000 0.103 12.034
ENSG00000176225 E038 1.5765464 0.036108542 0.664639195 0.86059139 18 70057742 70057832 91 - 0.445 0.370 -0.408
ENSG00000176225 E039 3.4194870 0.004218004 0.866444125 0.95399422 18 70059850 70060034 185 - 0.638 0.653 0.064
ENSG00000176225 E040 1.0877684 0.011472005 0.484562057 0.74869708 18 70060035 70060042 8 - 0.369 0.257 -0.730
ENSG00000176225 E041 0.0000000       18 70061312 70061400 89 -      
ENSG00000176225 E042 1.0980267 0.011091947 0.980418763 0.99781716 18 70065829 70065842 14 - 0.325 0.317 -0.052
ENSG00000176225 E043 2.4224758 0.005770553 0.372167295 0.66003982 18 70065843 70065922 80 - 0.591 0.460 -0.623
ENSG00000176225 E044 2.4144573 0.006044439 0.175399932 0.44942939 18 70073906 70073994 89 - 0.615 0.417 -0.952
ENSG00000176225 E045 0.0000000       18 70074759 70075351 593 -      
ENSG00000176225 E046 2.4192071 0.006279422 0.374064607 0.66176420 18 70075352 70075541 190 - 0.591 0.460 -0.623
ENSG00000176225 E047 0.0000000       18 70078609 70078738 130 -      
ENSG00000176225 E048 1.2165700 0.012607335 0.758197971 0.90510418 18 70086613 70086684 72 - 0.369 0.317 -0.315
ENSG00000176225 E049 2.4426754 0.007357049 0.990498706 1.00000000 18 70087989 70088147 159 - 0.538 0.534 -0.020
ENSG00000176225 E050 0.0000000       18 70091545 70091680 136 -      
ENSG00000176225 E051 1.7340562 0.008596758 0.146388539 0.40740305 18 70092110 70092186 77 - 0.325 0.534 1.118
ENSG00000176225 E052 0.7533131 0.014226769 0.054085444 0.23152983 18 70092187 70092220 34 - 0.087 0.370 2.592
ENSG00000176225 E053 1.2236523 0.018985117 0.748698186 0.90080282 18 70092676 70092804 129 - 0.325 0.370 0.270
ENSG00000176225 E054 1.8313883 0.008435586 0.886323081 0.96196545 18 70109498 70109640 143 - 0.445 0.460 0.077
ENSG00000176225 E055 1.1177292 0.159552221 0.284621205 0.57831881 18 70109641 70109717 77 - 0.222 0.417 1.270
ENSG00000176225 E056 1.8418702 0.008201659 0.512162801 0.76919951 18 70114445 70114599 155 - 0.408 0.498 0.463
ENSG00000176225 E057 1.4713765 0.011688136 0.722882031 0.88860331 18 70121556 70121700 145 - 0.369 0.417 0.270
ENSG00000176225 E058 2.2959688 0.005897225 0.238702576 0.52769540 18 70127502 70127741 240 - 0.591 0.417 -0.845
ENSG00000176225 E059 0.1187032 0.011860536 0.661773930   18 70128054 70128098 45 - 0.087 0.000 -11.599
ENSG00000176225 E060 3.5234885 0.034879885 0.738049761 0.89606681 18 70128358 70128546 189 - 0.680 0.626 -0.232
ENSG00000176225 E061 0.2442663 0.016402829 0.872079923   18 70128547 70131932 3386 - 0.087 0.103 0.270
ENSG00000176225 E062 1.7111088 0.214040021 0.693432817 0.87476272 18 70134473 70134541 69 - 0.408 0.460 0.272
ENSG00000176225 E063 0.8610974 0.012336136 0.517245025 0.77279407 18 70135184 70135280 97 - 0.222 0.317 0.685
ENSG00000176225 E064 0.0000000       18 70135281 70135290 10 -      
ENSG00000176225 E065 0.1268540 0.012480071 0.435187015   18 70138263 70138955 693 - 0.000 0.103 12.034
ENSG00000176225 E066 0.2455571 0.016468865 0.871390377   18 70139599 70139612 14 - 0.087 0.103 0.270
ENSG00000176225 E067 0.8286470 0.014489443 0.009353977 0.07696375 18 70139613 70139716 104 - 0.408 0.000 -14.407
ENSG00000176225 E068 0.0000000       18 70139717 70139932 216 -      
ENSG00000176225 E069 0.8263212 0.012480917 0.009247911 0.07644579 18 70140100 70140188 89 - 0.408 0.000 -14.407
ENSG00000176225 E070 0.6190673 0.145640399 0.531912182 0.78236392 18 70142288 70142387 100 - 0.160 0.257 0.855
ENSG00000176225 E071 0.8440702 0.013627917 0.379118988 0.66597412 18 70145612 70145783 172 - 0.325 0.187 -1.052
ENSG00000176225 E072 0.7086255 0.016341723 0.018252008 0.11929275 18 70148901 70149037 137 - 0.369 0.000 -14.184
ENSG00000176225 E073 0.3543453 0.016393500 0.149494054   18 70149971 70150087 117 - 0.222 0.000 -13.184
ENSG00000176225 E074 0.0000000       18 70150088 70150152 65 -      
ENSG00000176225 E075 0.5992382 0.014408225 0.253641387 0.54520076 18 70150608 70150733 126 - 0.277 0.103 -1.730
ENSG00000176225 E076 0.7264396 0.014386652 0.567571436 0.80532253 18 70166062 70166188 127 - 0.277 0.187 -0.730
ENSG00000176225 E077 0.3801504 0.021910996 0.069446032   18 70166434 70166918 485 - 0.000 0.257 13.619
ENSG00000176225 E078 1.5774955 0.008727758 0.643678286 0.84902708 18 70166919 70167031 113 - 0.445 0.370 -0.408
ENSG00000176225 E079 1.2222116 0.021518138 0.745755478 0.89946697 18 70168855 70168973 119 - 0.325 0.370 0.270
ENSG00000176225 E080 0.3802764 0.024033764 0.069471447   18 70168974 70169067 94 - 0.000 0.257 13.619
ENSG00000176225 E081 0.9791063 0.011958053 0.770578090 0.91150772 18 70176675 70176845 171 - 0.277 0.317 0.270
ENSG00000176225 E082 1.5867817 0.009006555 0.925847822 0.97773821 18 70188108 70188223 116 - 0.408 0.417 0.048
ENSG00000176225 E083 0.9807705 0.012475899 0.772597350 0.91241905 18 70190538 70190719 182 - 0.277 0.317 0.270
ENSG00000176225 E084 0.0000000       18 70193011 70193287 277 -      
ENSG00000176225 E085 0.9896818 0.070239294 0.343266265 0.63444442 18 70193288 70193453 166 - 0.222 0.370 1.006
ENSG00000176225 E086 0.0000000       18 70194146 70194736 591 -      
ENSG00000176225 E087 1.4625693 0.009447802 0.824389017 0.93626711 18 70196501 70196648 148 - 0.408 0.370 -0.215
ENSG00000176225 E088 0.4988535 0.018644306 0.230113747   18 70197624 70197738 115 - 0.087 0.257 1.855
ENSG00000176225 E089 0.6069811 0.014945472 0.826873472 0.93733645 18 70199414 70199504 91 - 0.222 0.187 -0.315
ENSG00000176225 E090 0.6154143 0.015876449 0.501677695 0.76157729 18 70201894 70201944 51 - 0.160 0.257 0.855
ENSG00000176225 E091 0.4889073 0.017654262 0.839498843   18 70201945 70201983 39 - 0.160 0.187 0.270
ENSG00000176225 E092 1.3146018 0.012538552 0.064029392 0.25491200 18 70204086 70204263 178 - 0.478 0.187 -1.900
ENSG00000176225 E093 1.0788033 0.011702730 0.160351430 0.42807474 18 70205128 70205315 188 - 0.408 0.187 -1.537
ENSG00000176225 E094 0.3625611 0.017038773 0.721006003   18 70205628 70205726 99 - 0.160 0.103 -0.730

Help

Please Click HERE to learn more details about the results from DEXseq.