ENSG00000176248

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000323927 ENSG00000176248 No_inf pgKDN_inf ANAPC2 protein_coding protein_coding 49.46369 61.46375 39.94524 2.908267 2.346285 -0.6215859 16.202382 10.045487 22.285842 1.5926164 0.7345990 1.1487917 0.35763333 0.16325 0.564150 0.400900 1.796184e-06 1.796184e-06 FALSE TRUE
ENST00000487917 ENSG00000176248 No_inf pgKDN_inf ANAPC2 protein_coding retained_intron 49.46369 61.46375 39.94524 2.908267 2.346285 -0.6215859 7.480455 12.805808 3.385723 0.4288573 0.2107279 -1.9161339 0.14248333 0.20925 0.085250 -0.124000 2.018474e-02 1.796184e-06 FALSE TRUE
ENST00000618649 ENSG00000176248 No_inf pgKDN_inf ANAPC2 protein_coding retained_intron 49.46369 61.46375 39.94524 2.908267 2.346285 -0.6215859 5.595342 9.066951 2.948579 0.2575946 0.4866897 -1.6173035 0.10767500 0.14795 0.073175 -0.074775 2.634500e-01 1.796184e-06 FALSE TRUE
MSTRG.29541.10 ENSG00000176248 No_inf pgKDN_inf ANAPC2 protein_coding   49.46369 61.46375 39.94524 2.908267 2.346285 -0.6215859 3.263074 3.895046 1.580000 0.7417572 0.9966399 -1.2963125 0.06465000 0.06315 0.037600 -0.025550 6.520363e-01 1.796184e-06 FALSE TRUE
MSTRG.29541.3 ENSG00000176248 No_inf pgKDN_inf ANAPC2 protein_coding   49.46369 61.46375 39.94524 2.908267 2.346285 -0.6215859 3.930566 5.350815 3.268817 1.3556779 0.4807589 -0.7092771 0.07871667 0.08495 0.082400 -0.002550 1.000000e+00 1.796184e-06 FALSE TRUE
MSTRG.29541.6 ENSG00000176248 No_inf pgKDN_inf ANAPC2 protein_coding   49.46369 61.46375 39.94524 2.908267 2.346285 -0.6215859 7.006105 11.699944 2.389788 1.2564072 1.2112919 -2.2867552 0.13307500 0.19200 0.060425 -0.131575 2.340541e-01 1.796184e-06 TRUE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000176248 E001 0.0000000       9 137174784 137174787 4 -      
ENSG00000176248 E002 0.7532517 0.0133242456 2.527595e-01 5.441180e-01 9 137174788 137174792 5 - 0.117 0.294 1.649
ENSG00000176248 E003 1.1179204 0.0110121302 7.473277e-01 9.002771e-01 9 137174793 137174794 2 - 0.285 0.335 0.327
ENSG00000176248 E004 67.2345028 0.0002464854 5.952031e-01 8.220207e-01 9 137174795 137175154 360 - 1.831 1.811 -0.066
ENSG00000176248 E005 3.7644347 0.0038330605 9.559008e-03 7.806716e-02 9 137175155 137175236 82 - 0.406 0.767 1.649
ENSG00000176248 E006 33.7010605 0.0004602504 9.258709e-01 9.777382e-01 9 137175237 137175273 37 - 1.528 1.523 -0.017
ENSG00000176248 E007 22.2892518 0.0006578565 3.453717e-01 6.363949e-01 9 137175274 137175274 1 - 1.389 1.329 -0.207
ENSG00000176248 E008 28.1261954 0.0004933339 6.733734e-01 8.647661e-01 9 137175275 137175297 23 - 1.464 1.440 -0.083
ENSG00000176248 E009 31.2154646 0.0005679307 6.566120e-01 8.563072e-01 9 137175298 137175331 34 - 1.508 1.484 -0.083
ENSG00000176248 E010 51.8889227 0.0002756888 2.355682e-01 5.249622e-01 9 137175332 137175468 137 - 1.739 1.689 -0.168
ENSG00000176248 E011 14.6525516 0.0010702360 4.430690e-01 7.182161e-01 9 137175469 137175472 4 - 1.216 1.158 -0.208
ENSG00000176248 E012 10.1069429 0.0035561320 9.942309e-03 7.995057e-02 9 137175473 137175707 235 - 0.856 1.108 0.936
ENSG00000176248 E013 36.8441669 0.0004221703 2.983026e-01 5.913000e-01 9 137175708 137175837 130 - 1.595 1.543 -0.176
ENSG00000176248 E014 8.2886732 0.0016522293 3.320221e-05 9.397231e-04 9 137175838 137176002 165 - 0.612 1.074 1.812
ENSG00000176248 E015 108.8053553 0.0001621790 9.389681e-44 1.055048e-40 9 137176003 137178116 2114 - 1.689 2.144 1.529
ENSG00000176248 E016 41.5555996 0.0003664009 2.041223e-02 1.285663e-01 9 137180181 137180384 204 - 1.678 1.571 -0.365
ENSG00000176248 E017 23.1734510 0.0006049591 5.000126e-01 7.601980e-01 9 137180452 137180527 76 - 1.394 1.353 -0.145
ENSG00000176248 E018 0.8805141 0.0124042486 1.640836e-01 4.332771e-01 9 137180763 137180787 25 - 0.117 0.335 1.912
ENSG00000176248 E019 33.6683180 0.0009760746 1.845209e-02 1.201994e-01 9 137180788 137180929 142 - 1.598 1.475 -0.420
ENSG00000176248 E020 12.0127583 0.0250260813 8.500784e-02 3.014341e-01 9 137181681 137181681 1 - 1.200 1.029 -0.614
ENSG00000176248 E021 34.8611429 0.0004227366 2.919676e-03 3.382569e-02 9 137181682 137181814 133 - 1.628 1.478 -0.510
ENSG00000176248 E022 21.9562978 0.0006345680 7.155989e-01 8.853259e-01 9 137181815 137181862 48 - 1.361 1.337 -0.081
ENSG00000176248 E023 29.2858867 0.0004774194 7.500335e-01 9.014575e-01 9 137183125 137183242 118 - 1.455 1.473 0.061
ENSG00000176248 E024 0.0000000       9 137183243 137183614 372 -      
ENSG00000176248 E025 32.7348953 0.0004434454 9.066189e-02 3.127244e-01 9 137183672 137183782 111 - 1.566 1.478 -0.302
ENSG00000176248 E026 16.6945557 0.0008266790 4.455797e-02 2.063391e-01 9 137183783 137183791 9 - 1.318 1.175 -0.503
ENSG00000176248 E027 41.3642386 0.0058758821 6.419840e-03 5.928898e-02 9 137184913 137185087 175 - 1.700 1.550 -0.510
ENSG00000176248 E028 3.4918150 0.0043248545 1.333234e-01 3.878301e-01 9 137185177 137185414 238 - 0.500 0.705 0.912
ENSG00000176248 E029 27.5414852 0.0045575182 7.963530e-04 1.256230e-02 9 137186224 137186356 133 - 1.559 1.352 -0.712
ENSG00000176248 E030 6.6372771 0.0164173785 4.296692e-03 4.463363e-02 9 137186357 137186516 160 - 0.612 0.970 1.431
ENSG00000176248 E031 28.2315543 0.0004862201 5.741407e-07 2.820192e-05 9 137186673 137187480 808 - 1.232 1.541 1.069
ENSG00000176248 E032 77.7165605 0.0003168577 2.314979e-05 6.980626e-04 9 137187481 137188103 623 - 1.965 1.823 -0.477
ENSG00000176248 E033 11.0215482 0.0012668226 2.874515e-02 1.588270e-01 9 137188416 137188581 166 - 1.173 0.988 -0.673

Help

Please Click HERE to learn more details about the results from DEXseq.