ENSG00000176853

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000334705 ENSG00000176853 No_inf pgKDN_inf FAM91A1 protein_coding protein_coding 36.74631 32.42562 44.22933 0.8870293 0.8935622 0.4477505 15.3223911 5.916662 19.524394 0.8080709 1.8134761 1.72072482 0.41294167 0.183825 0.442975 0.25915 0.0144687 0.0144687 FALSE TRUE
ENST00000518333 ENSG00000176853 No_inf pgKDN_inf FAM91A1 protein_coding retained_intron 36.74631 32.42562 44.22933 0.8870293 0.8935622 0.4477505 6.4082158 8.352039 8.181602 3.0767624 3.1916140 -0.02970926 0.17172500 0.253025 0.181175 -0.07185 0.9319162 0.0144687 FALSE FALSE
ENST00000518976 ENSG00000176853 No_inf pgKDN_inf FAM91A1 protein_coding nonsense_mediated_decay 36.74631 32.42562 44.22933 0.8870293 0.8935622 0.4477505 4.4803762 7.183568 2.882111 1.5942725 1.7386341 -1.31458452 0.12964167 0.223600 0.066850 -0.15675 0.3482983 0.0144687   FALSE
ENST00000520246 ENSG00000176853 No_inf pgKDN_inf FAM91A1 protein_coding retained_intron 36.74631 32.42562 44.22933 0.8870293 0.8935622 0.4477505 0.6748152 2.024446 0.000000 1.1688825 0.0000000 -7.66849184 0.02101667 0.063050 0.000000 -0.06305 0.4408691 0.0144687   FALSE
ENST00000521166 ENSG00000176853 No_inf pgKDN_inf FAM91A1 protein_coding protein_coding 36.74631 32.42562 44.22933 0.8870293 0.8935622 0.4477505 2.4332112 1.734340 2.737915 1.0024813 0.3451004 0.65565628 0.06640833 0.053175 0.061975 0.00880 0.8060356 0.0144687 FALSE TRUE
MSTRG.28176.4 ENSG00000176853 No_inf pgKDN_inf FAM91A1 protein_coding   36.74631 32.42562 44.22933 0.8870293 0.8935622 0.4477505 5.9149266 5.947172 8.495260 1.2230980 3.2323714 0.51372773 0.16026667 0.186175 0.195275 0.00910 0.9730107 0.0144687 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000176853 E001 0.2357071 0.0157293042 4.238519e-01   8 123768439 123768455 17 + 0.141 0.000 -9.480
ENSG00000176853 E002 8.5244325 0.0016292896 5.627754e-03 5.396041e-02 8 123768456 123768645 190 + 1.055 0.800 -0.961
ENSG00000176853 E003 11.5978700 0.0075115305 1.161476e-01 3.592949e-01 8 123768646 123768774 129 + 1.135 1.016 -0.432
ENSG00000176853 E004 0.2533610 0.0160590529 1.285609e-01   8 123772994 123773032 39 + 0.000 0.211 11.757
ENSG00000176853 E005 12.0838593 0.0012445901 7.605443e-02 2.818995e-01 8 123774080 123774164 85 + 1.153 1.029 -0.448
ENSG00000176853 E006 15.9804538 0.0020536441 1.446260e-01 4.048211e-01 8 123775147 123775298 152 + 1.252 1.169 -0.294
ENSG00000176853 E007 10.5826689 0.0099045245 9.284285e-01 9.787698e-01 8 123777265 123777322 58 + 1.048 1.066 0.065
ENSG00000176853 E008 13.1707979 0.0011857508 4.126037e-01 6.937651e-01 8 123778025 123778092 68 + 1.103 1.196 0.330
ENSG00000176853 E009 21.0626052 0.0064539163 1.678004e-01 4.386839e-01 8 123778659 123778772 114 + 1.362 1.289 -0.257
ENSG00000176853 E010 15.0988354 0.0017513380 3.534412e-02 1.799707e-01 8 123779985 123780026 42 + 1.247 1.110 -0.489
ENSG00000176853 E011 14.5178980 0.0009720794 2.211788e-01 5.082355e-01 8 123780027 123780075 49 + 1.208 1.140 -0.240
ENSG00000176853 E012 0.3625611 0.0165638402 8.836094e-01   8 123780076 123780082 7 + 0.141 0.118 -0.294
ENSG00000176853 E013 14.5168779 0.0268463378 4.627840e-01 7.329899e-01 8 123780480 123780542 63 + 1.202 1.150 -0.186
ENSG00000176853 E014 20.0492792 0.0018426552 3.030926e-02 1.638468e-01 8 123784470 123784576 107 + 1.359 1.237 -0.426
ENSG00000176853 E015 0.0000000       8 123784577 123784795 219 +      
ENSG00000176853 E016 10.5107915 0.0014129315 1.545918e-01 4.200438e-01 8 123785081 123785119 39 + 1.090 0.989 -0.369
ENSG00000176853 E017 16.0901108 0.0008365853 1.707152e-01 4.430277e-01 8 123785629 123785741 113 + 1.252 1.178 -0.262
ENSG00000176853 E018 0.7288029 0.5268797468 9.102730e-01 9.715752e-01 8 123786004 123786151 148 + 0.248 0.211 -0.297
ENSG00000176853 E019 19.7972428 0.0006820231 1.536123e-02 1.068609e-01 8 123786495 123786610 116 + 1.359 1.221 -0.483
ENSG00000176853 E020 22.1999146 0.0006271961 3.757070e-03 4.065687e-02 8 123787261 123787373 113 + 1.414 1.252 -0.561
ENSG00000176853 E021 16.6263590 0.0007978356 3.083573e-03 3.521267e-02 8 123787664 123787750 87 + 1.305 1.110 -0.690
ENSG00000176853 E022 20.5351325 0.0010760317 1.840420e-05 5.740959e-04 8 123789613 123789745 133 + 1.414 1.140 -0.959
ENSG00000176853 E023 14.6167266 0.0013058355 6.376659e-02 2.542085e-01 8 123798090 123798238 149 + 1.228 1.110 -0.421
ENSG00000176853 E024 22.4126876 0.0147329335 4.629427e-01 7.330696e-01 8 123799520 123799654 135 + 1.325 1.410 0.296
ENSG00000176853 E025 10.8726850 0.0021874063 1.544394e-01 4.198566e-01 8 123799772 123799885 114 + 1.000 1.150 0.544
ENSG00000176853 E026 14.8864343 0.0009336763 2.133697e-01 4.986215e-01 8 123805267 123805339 73 + 1.218 1.150 -0.241
ENSG00000176853 E027 31.8611777 0.0005023502 1.550501e-01 4.207321e-01 8 123806080 123806229 150 + 1.526 1.478 -0.164
ENSG00000176853 E028 28.5245874 0.0005430045 1.258035e-02 9.321453e-02 8 123808272 123808376 105 + 1.503 1.388 -0.396
ENSG00000176853 E029 0.2356421 0.0156933639 4.240227e-01   8 123808759 123808892 134 + 0.141 0.000 -11.764
ENSG00000176853 E030 16.0574514 0.0010441747 2.312300e-02 1.387007e-01 8 123808893 123808906 14 + 1.275 1.130 -0.511
ENSG00000176853 E031 15.3127414 0.0008620826 1.421278e-02 1.013064e-01 8 123808907 123808928 22 + 1.261 1.099 -0.576
ENSG00000176853 E032 20.8082484 0.0006641456 1.111984e-01 3.501504e-01 8 123808929 123809016 88 + 1.359 1.282 -0.269
ENSG00000176853 E033 16.8104529 0.0010223297 1.144806e-01 3.564687e-01 8 123810282 123810351 70 + 1.275 1.187 -0.310
ENSG00000176853 E034 19.5885735 0.0007456289 3.831221e-06 1.491936e-04 8 123810352 123811455 1104 + 1.141 1.474 1.164
ENSG00000176853 E035 3.9681650 0.0036651071 1.003364e-03 1.504461e-02 8 123812056 123812177 122 + 0.465 0.896 1.844
ENSG00000176853 E036 482.0063062 0.0018353706 1.033994e-12 1.347039e-10 8 123812519 123815452 2934 + 2.621 2.746 0.416

Help

Please Click HERE to learn more details about the results from DEXseq.