ENSG00000176915

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000357997 ENSG00000176915 No_inf pgKDN_inf ANKLE2 protein_coding protein_coding 42.22391 27.68168 49.29849 0.5207115 2.301741 0.8323834 10.601921 3.081899 15.439756 1.10826360 2.6577778 2.3210191 0.23397500 0.112600 0.317875 0.205275 0.362859890 0.007003751 FALSE TRUE
ENST00000542282 ENSG00000176915 No_inf pgKDN_inf ANKLE2 protein_coding protein_coding 42.22391 27.68168 49.29849 0.5207115 2.301741 0.8323834 1.923853 2.782406 1.178975 0.19263130 0.4970708 -1.2317899 0.05360000 0.100425 0.023075 -0.077350 0.135944045 0.007003751 FALSE TRUE
ENST00000542374 ENSG00000176915 No_inf pgKDN_inf ANKLE2 protein_coding protein_coding_CDS_not_defined 42.22391 27.68168 49.29849 0.5207115 2.301741 0.8323834 4.310622 0.290870 7.700338 0.29087005 1.6209492 4.6795816 0.08375833 0.010325 0.153050 0.142725 0.007003751 0.007003751 FALSE FALSE
MSTRG.7487.4 ENSG00000176915 No_inf pgKDN_inf ANKLE2 protein_coding   42.22391 27.68168 49.29849 0.5207115 2.301741 0.8323834 13.858430 10.381009 13.374555 1.14780914 2.4615546 0.3652334 0.33611667 0.373950 0.271400 -0.102550 0.630389888 0.007003751 TRUE TRUE
MSTRG.7487.6 ENSG00000176915 No_inf pgKDN_inf ANKLE2 protein_coding   42.22391 27.68168 49.29849 0.5207115 2.301741 0.8323834 5.468831 6.486020 5.019494 0.07575557 0.5100988 -0.3691429 0.14547500 0.234625 0.101300 -0.133325 0.050680556 0.007003751 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000176915 E001 0.6087439 0.0143997301 9.679229e-01 9.935284e-01 12 132725503 132725649 147 - 0.207 0.201 -0.048
ENSG00000176915 E002 0.3628435 0.0166703795 8.387553e-01   12 132725650 132725667 18 - 0.148 0.112 -0.463
ENSG00000176915 E003 0.7259974 0.0344823834 7.087382e-01 8.819572e-01 12 132725668 132725671 4 - 0.258 0.201 -0.464
ENSG00000176915 E004 198.9340451 0.0001436271 5.058897e-02 2.222964e-01 12 132725672 132726805 1134 - 2.279 2.319 0.133
ENSG00000176915 E005 41.5797493 0.0026875362 2.841861e-01 5.779304e-01 12 132726806 132727132 327 - 1.600 1.655 0.188
ENSG00000176915 E006 25.6935748 0.0009148156 6.058893e-01 8.283825e-01 12 132727133 132727285 153 - 1.408 1.440 0.110
ENSG00000176915 E007 20.2183991 0.0007102578 6.243375e-01 8.384089e-01 12 132727286 132727349 64 - 1.308 1.341 0.116
ENSG00000176915 E008 29.3214643 0.0024408653 9.469217e-01 9.858971e-01 12 132727350 132727443 94 - 1.478 1.476 -0.009
ENSG00000176915 E009 35.1950158 0.0003789554 2.470884e-01 5.376610e-01 12 132728032 132728163 132 - 1.577 1.520 -0.195
ENSG00000176915 E010 21.0689600 0.0076787674 6.587280e-01 8.574354e-01 12 132729679 132729722 44 - 1.325 1.358 0.117
ENSG00000176915 E011 100.9583571 0.0001724395 3.761889e-01 6.633891e-01 12 132729723 132730232 510 - 1.992 2.019 0.091
ENSG00000176915 E012 19.7209790 0.0006903743 9.037287e-01 9.690691e-01 12 132730233 132730270 38 - 1.308 1.317 0.033
ENSG00000176915 E013 5.4996921 0.0055085653 1.647674e-06 7.190575e-05 12 132730271 132730689 419 - 0.482 1.042 2.302
ENSG00000176915 E014 20.1375879 0.0038219817 3.385206e-07 1.753868e-05 12 132730690 132732210 1521 - 1.134 1.488 1.240
ENSG00000176915 E015 2.2025091 0.0064801477 4.420547e-01 7.173912e-01 12 132733996 132734071 76 - 0.452 0.563 0.537
ENSG00000176915 E016 29.4746088 0.0005412699 6.901989e-01 8.727995e-01 12 132734385 132734496 112 - 1.469 1.492 0.080
ENSG00000176915 E017 20.2405186 0.0007916897 1.910955e-01 4.704466e-01 12 132734497 132734575 79 - 1.357 1.272 -0.298
ENSG00000176915 E018 13.0813558 0.0140753500 9.272750e-04 1.416761e-02 12 132734576 132734967 392 - 0.989 1.292 1.087
ENSG00000176915 E019 12.7561062 0.0010283868 2.421721e-02 1.425752e-01 12 132734968 132735405 438 - 1.048 1.228 0.648
ENSG00000176915 E020 11.7118904 0.0289191141 1.613150e-01 4.293901e-01 12 132735406 132735406 1 - 1.159 1.006 -0.553
ENSG00000176915 E021 23.6834289 0.0026251036 6.022642e-01 8.263800e-01 12 132735407 132735512 106 - 1.401 1.369 -0.110
ENSG00000176915 E022 24.1606364 0.0008263816 4.033431e-03 4.267982e-02 12 132736893 132737042 150 - 1.463 1.285 -0.618
ENSG00000176915 E023 14.3111450 0.0076810649 5.172032e-04 8.974349e-03 12 132737043 132737065 23 - 1.285 0.980 -1.098
ENSG00000176915 E024 10.6179230 0.0012941730 1.234008e-04 2.820126e-03 12 132737066 132738907 1842 - 0.887 1.221 1.220
ENSG00000176915 E025 23.7628453 0.0006122443 1.812001e-01 4.570381e-01 12 132741419 132741485 67 - 1.422 1.341 -0.279
ENSG00000176915 E026 2.2384518 0.0640980473 1.939248e-02 1.244839e-01 12 132741486 132741808 323 - 0.304 0.684 1.915
ENSG00000176915 E027 1.8221410 0.0108114439 9.435524e-01 9.844003e-01 12 132741809 132741891 83 - 0.452 0.442 -0.048
ENSG00000176915 E028 2.8405878 0.0539193129 1.006274e-01 3.311909e-01 12 132741892 132742558 667 - 0.452 0.710 1.174
ENSG00000176915 E029 23.8070197 0.0005581396 5.458403e-01 7.916696e-01 12 132743154 132743238 85 - 1.405 1.369 -0.122
ENSG00000176915 E030 16.0058934 0.0009037226 2.158607e-01 5.017987e-01 12 132743239 132743276 38 - 1.262 1.172 -0.318
ENSG00000176915 E031 32.0172130 0.0004234222 1.303348e-01 3.829806e-01 12 132747832 132748020 189 - 1.546 1.467 -0.271
ENSG00000176915 E032 33.2644395 0.0020516173 7.423594e-03 6.572293e-02 12 132748138 132748331 194 - 1.587 1.440 -0.503
ENSG00000176915 E033 0.1268540 0.0123268576 3.683598e-01   12 132748887 132749027 141 - 0.000 0.112 9.778
ENSG00000176915 E034 33.9900719 0.0004477569 1.123384e-05 3.774991e-04 12 132750643 132750849 207 - 1.624 1.391 -0.800
ENSG00000176915 E035 0.1272623 0.0124291795 3.682736e-01   12 132750850 132751334 485 - 0.000 0.112 9.777
ENSG00000176915 E036 48.7888862 0.0003499043 5.565930e-03 5.354850e-02 12 132754675 132755133 459 - 1.739 1.620 -0.405
ENSG00000176915 E037 2.7195233 0.0053000804 3.403438e-02 1.757742e-01 12 132755134 132756633 1500 - 0.419 0.710 1.344
ENSG00000176915 E038 10.1728232 0.0306061653 1.720342e-01 4.447424e-01 12 132756634 132761617 4984 - 0.970 1.127 0.572
ENSG00000176915 E039 14.8729094 0.0270598164 2.005564e-01 4.826348e-01 12 132761618 132761914 297 - 1.247 1.117 -0.463

Help

Please Click HERE to learn more details about the results from DEXseq.