ENSG00000177189

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000379565 ENSG00000177189 No_inf pgKDN_inf RPS6KA3 protein_coding protein_coding 42.20472 28.24716 51.348 1.216144 0.5237177 0.8619724 5.629288 3.0780490 6.209046 0.7098444 0.5866026 1.00999761 0.13202500 0.112550 0.121075 0.008525 0.9406278002 0.0002291792 FALSE TRUE
ENST00000457145 ENSG00000177189 No_inf pgKDN_inf RPS6KA3 protein_coding protein_coding 42.20472 28.24716 51.348 1.216144 0.5237177 0.8619724 4.320540 0.0000000 5.925934 0.0000000 3.6380260 9.21333130 0.08989167 0.000000 0.116100 0.116100 0.5779235576 0.0002291792 FALSE TRUE
ENST00000643073 ENSG00000177189 No_inf pgKDN_inf RPS6KA3 protein_coding nonsense_mediated_decay 42.20472 28.24716 51.348 1.216144 0.5237177 0.8619724 6.317319 0.0000000 7.428143 0.0000000 3.2972850 9.53879868 0.12809167 0.000000 0.144325 0.144325 0.0330200286 0.0002291792 FALSE TRUE
ENST00000647265 ENSG00000177189 No_inf pgKDN_inf RPS6KA3 protein_coding protein_coding 42.20472 28.24716 51.348 1.216144 0.5237177 0.8619724 2.365970 0.8407109 4.499032 0.5049459 2.2796010 2.40607705 0.05053333 0.027875 0.087325 0.059450 0.7932030678 0.0002291792 FALSE TRUE
MSTRG.29777.2 ENSG00000177189 No_inf pgKDN_inf RPS6KA3 protein_coding   42.20472 28.24716 51.348 1.216144 0.5237177 0.8619724 20.191071 20.9426144 22.317815 0.2441610 1.2925897 0.09171179 0.51650000 0.746075 0.434475 -0.311600 0.0002291792 0.0002291792 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000177189 E001 1.4148552 8.878293e-03 7.064951e-04 1.142209e-02 X 20149911 20149948 38 - 0.546 0.000 -12.718
ENSG00000177189 E002 589.7779744 4.880279e-05 1.517203e-25 6.392877e-23 X 20149949 20153661 3713 - 2.719 2.824 0.348
ENSG00000177189 E003 14.3353424 9.457698e-04 7.642969e-02 2.826882e-01 X 20153662 20153806 145 - 1.120 1.252 0.469
ENSG00000177189 E004 65.3096027 3.180522e-04 6.149067e-01 8.327528e-01 X 20153807 20154589 783 - 1.812 1.828 0.054
ENSG00000177189 E005 30.6140179 4.653824e-04 4.420324e-01 7.173766e-01 X 20154590 20154750 161 - 1.480 1.518 0.133
ENSG00000177189 E006 15.9966928 1.337249e-03 5.203647e-01 7.747076e-01 X 20154751 20154786 36 - 1.207 1.252 0.157
ENSG00000177189 E007 11.7328794 1.173086e-03 3.616537e-01 6.511052e-01 X 20154787 20154795 9 - 1.068 1.141 0.264
ENSG00000177189 E008 14.6260004 9.356135e-04 8.046481e-01 9.276820e-01 X 20154796 20154834 39 - 1.184 1.200 0.057
ENSG00000177189 E009 10.1098128 1.492746e-03 9.941750e-01 1.000000e+00 X 20154835 20154845 11 - 1.044 1.041 -0.011
ENSG00000177189 E010 23.8401466 4.166949e-03 7.190838e-01 8.868075e-01 X 20154846 20154931 86 - 1.404 1.377 -0.092
ENSG00000177189 E011 22.5198472 6.467253e-04 9.905485e-01 1.000000e+00 X 20154932 20154965 34 - 1.370 1.367 -0.012
ENSG00000177189 E012 17.5911419 7.750841e-04 2.997342e-01 5.926082e-01 X 20154966 20154977 12 - 1.234 1.304 0.244
ENSG00000177189 E013 86.2520643 2.002267e-04 9.516887e-02 3.211637e-01 X 20154978 20155256 279 - 1.962 1.905 -0.192
ENSG00000177189 E014 64.0089383 4.397887e-03 1.338112e-01 3.887596e-01 X 20155257 20155440 184 - 1.840 1.768 -0.242
ENSG00000177189 E015 40.1356690 6.674978e-04 7.174151e-01 8.862883e-01 X 20155441 20155520 80 - 1.620 1.600 -0.068
ENSG00000177189 E016 55.9005064 2.937891e-04 2.121590e-01 4.973739e-01 X 20156109 20156249 141 - 1.775 1.722 -0.180
ENSG00000177189 E017 48.8709924 3.308390e-03 4.372393e-01 7.135284e-01 X 20161644 20161761 118 - 1.712 1.672 -0.138
ENSG00000177189 E018 34.1054238 6.911281e-04 2.039747e-01 4.866393e-01 X 20162964 20163040 77 - 1.572 1.503 -0.235
ENSG00000177189 E019 29.6129737 5.409276e-04 1.547902e-01 4.203442e-01 X 20164899 20164961 63 - 1.517 1.436 -0.280
ENSG00000177189 E020 34.7638446 4.058260e-04 1.099179e-02 8.558829e-02 X 20164962 20165060 99 - 1.605 1.471 -0.459
ENSG00000177189 E021 43.2692892 1.008202e-03 3.325597e-01 6.246962e-01 X 20167589 20167747 159 - 1.664 1.615 -0.164
ENSG00000177189 E022 29.0815153 4.102215e-03 8.296534e-01 9.382722e-01 X 20169402 20169491 90 - 1.483 1.466 -0.056
ENSG00000177189 E023 31.8886478 4.720387e-04 7.474445e-01 9.002888e-01 X 20172746 20172868 123 - 1.523 1.503 -0.068
ENSG00000177189 E024 10.9930399 1.277730e-03 2.605395e-02 1.492742e-01 X 20172869 20172871 3 - 1.153 0.954 -0.726
ENSG00000177189 E025 33.9291564 5.082421e-04 1.991556e-02 1.266889e-01 X 20175164 20175288 125 - 1.591 1.466 -0.426
ENSG00000177189 E026 31.1992399 4.448500e-04 1.854710e-01 4.631535e-01 X 20176250 20176352 103 - 1.536 1.462 -0.254
ENSG00000177189 E027 23.0547870 7.451965e-03 3.010979e-01 5.941404e-01 X 20176434 20176498 65 - 1.411 1.334 -0.268
ENSG00000177189 E028 27.2127520 2.321456e-03 4.762541e-01 7.428077e-01 X 20176996 20177084 89 - 1.467 1.422 -0.157
ENSG00000177189 E029 25.8025835 5.217982e-04 8.376424e-01 9.418239e-01 X 20186296 20186366 71 - 1.432 1.417 -0.051
ENSG00000177189 E030 41.0449501 5.397372e-03 7.766601e-03 6.770387e-02 X 20187828 20187970 143 - 1.681 1.529 -0.518
ENSG00000177189 E031 20.6486233 1.422019e-02 2.038036e-02 1.284312e-01 X 20188497 20188534 38 - 1.407 1.215 -0.671
ENSG00000177189 E032 33.2385153 4.933218e-04 5.403779e-04 9.274686e-03 X 20193487 20193593 107 - 1.605 1.417 -0.643
ENSG00000177189 E033 26.0108299 2.038052e-03 8.024915e-03 6.927269e-02 X 20194189 20194268 80 - 1.494 1.328 -0.576
ENSG00000177189 E034 25.5699099 4.024647e-03 9.162676e-04 1.404319e-02 X 20195065 20195145 81 - 1.506 1.285 -0.765
ENSG00000177189 E035 0.7439701 1.413734e-01 2.885117e-01 5.820431e-01 X 20203362 20204021 660 - 0.152 0.331 1.445
ENSG00000177189 E036 17.8174700 2.119170e-02 3.579034e-01 6.474095e-01 X 20204022 20204065 44 - 1.307 1.223 -0.297
ENSG00000177189 E037 15.7726207 7.414406e-03 4.299016e-01 7.079389e-01 X 20204066 20204103 38 - 1.250 1.184 -0.234
ENSG00000177189 E038 22.7036945 5.625585e-03 4.348270e-01 7.118951e-01 X 20209288 20209404 117 - 1.397 1.339 -0.199
ENSG00000177189 E039 0.1272623 1.237119e-02 3.904075e-01   X 20218800 20218959 160 - 0.000 0.109 11.300
ENSG00000177189 E040 13.3207983 4.703347e-03 1.721659e-01 4.448390e-01 X 20234758 20234814 57 - 1.201 1.084 -0.420
ENSG00000177189 E041 0.0000000       X 20235493 20235513 21 -      
ENSG00000177189 E042 1.5718852 2.266077e-02 4.125231e-01 6.937541e-01 X 20240569 20240605 37 - 0.461 0.331 -0.726
ENSG00000177189 E043 0.8445366 1.021610e-01 5.035492e-01 7.630270e-01 X 20240606 20240669 64 - 0.312 0.196 -0.878
ENSG00000177189 E044 1.7087527 1.089949e-02 9.619866e-01 9.916848e-01 X 20241593 20241686 94 - 0.428 0.433 0.029
ENSG00000177189 E045 0.5067220 4.598267e-02 2.282429e-02 1.376963e-01 X 20259847 20259914 68 - 0.000 0.331 12.969
ENSG00000177189 E046 0.2373413 1.575909e-02 3.698232e-01   X 20265499 20265617 119 - 0.152 0.000 -12.616
ENSG00000177189 E047 0.0000000       X 20265923 20266100 178 -      
ENSG00000177189 E048 6.0614990 2.991620e-03 3.775088e-01 6.645091e-01 X 20266564 20266941 378 - 0.887 0.788 -0.386
ENSG00000177189 E049 0.3731018 1.672466e-02 4.073691e-01   X 20267039 20267382 344 - 0.083 0.196 1.444
ENSG00000177189 E050 0.0000000       X 20267383 20267519 137 -      

Help

Please Click HERE to learn more details about the results from DEXseq.