ENSG00000177239

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000371589 ENSG00000177239 No_inf pgKDN_inf MAN1B1 protein_coding protein_coding 78.47499 80.29155 72.46671 1.51289 2.409622 -0.1479103 32.59915 23.18699 40.67747 3.481139 1.871103 0.8106468 0.4198667 0.287425 0.5619 0.274475 0.001157187 0.001157187 FALSE TRUE
ENST00000550113 ENSG00000177239 No_inf pgKDN_inf MAN1B1 protein_coding retained_intron 78.47499 80.29155 72.46671 1.51289 2.409622 -0.1479103 26.09213 31.68654 17.32952 2.042657 3.164221 -0.8702612 0.3280583 0.394575 0.2357 -0.158875 0.165773132 0.001157187 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000177239 E001 0.0000000       9 137086857 137086869 13 +      
ENSG00000177239 E002 0.1265070 0.0123608257 6.709712e-01   9 137086870 137086893 24 + 0.000 0.086 8.624
ENSG00000177239 E003 0.2452102 0.0164825038 8.622116e-01   9 137086894 137086903 10 + 0.105 0.086 -0.315
ENSG00000177239 E004 0.2452102 0.0164825038 8.622116e-01   9 137086904 137086910 7 + 0.105 0.086 -0.315
ENSG00000177239 E005 0.3622142 0.0165680345 4.543823e-01   9 137086911 137086935 25 + 0.189 0.086 -1.315
ENSG00000177239 E006 0.3622142 0.0165680345 4.543823e-01   9 137086936 137086950 15 + 0.189 0.086 -1.315
ENSG00000177239 E007 0.3622142 0.0165680345 4.543823e-01   9 137086951 137086956 6 + 0.189 0.086 -1.315
ENSG00000177239 E008 0.3622142 0.0165680345 4.543823e-01   9 137086957 137086962 6 + 0.189 0.086 -1.315
ENSG00000177239 E009 0.2357071 0.0157205520 1.749516e-01   9 137086963 137086964 2 + 0.189 0.000 -13.028
ENSG00000177239 E010 0.2357071 0.0157205520 1.749516e-01   9 137086965 137086965 1 + 0.189 0.000 -13.028
ENSG00000177239 E011 0.7161162 0.0135175374 5.210422e-02 2.266647e-01 9 137086966 137086975 10 + 0.374 0.086 -2.637
ENSG00000177239 E012 1.9565124 0.0137586921 6.625609e-01 8.593550e-01 9 137086976 137086979 4 + 0.503 0.440 -0.315
ENSG00000177239 E013 2.9345763 0.0291069116 6.184352e-01 8.349577e-01 9 137086980 137086984 5 + 0.631 0.560 -0.315
ENSG00000177239 E014 12.7404295 0.0010782356 3.502630e-01 6.405086e-01 9 137086985 137087083 99 + 1.174 1.101 -0.260
ENSG00000177239 E015 21.7242637 0.0013286885 8.467966e-03 7.184384e-02 9 137087084 137087218 135 + 1.439 1.274 -0.575
ENSG00000177239 E016 0.2352613 0.2668682718 2.293158e-01   9 137087219 137087357 139 + 0.189 0.000 -12.071
ENSG00000177239 E017 0.0000000       9 137087358 137087363 6 +      
ENSG00000177239 E018 0.0000000       9 137087364 137087566 203 +      
ENSG00000177239 E019 37.6081304 0.0003980320 7.456717e-02 2.784151e-01 9 137088075 137088183 109 + 1.628 1.544 -0.287
ENSG00000177239 E020 0.0000000       9 137088184 137088267 84 +      
ENSG00000177239 E021 1.1340015 0.0113220572 3.185877e-02 1.686924e-01 9 137088268 137088398 131 + 0.105 0.440 2.685
ENSG00000177239 E022 0.2541163 0.0160636266 3.286583e-01   9 137088399 137088560 162 + 0.000 0.158 11.941
ENSG00000177239 E023 31.5264744 0.0005284306 8.004877e-03 6.916614e-02 9 137088869 137088952 84 + 1.581 1.444 -0.472
ENSG00000177239 E024 25.7481645 0.0005428671 2.305076e-01 5.190056e-01 9 137088953 137089005 53 + 1.460 1.393 -0.233
ENSG00000177239 E025 0.0000000       9 137089181 137089278 98 +      
ENSG00000177239 E026 0.0000000       9 137089279 137089291 13 +      
ENSG00000177239 E027 15.5148268 0.0152380382 7.958116e-01 9.225031e-01 9 137096237 137096239 3 + 1.197 1.225 0.100
ENSG00000177239 E028 48.0648015 0.0023156314 8.118627e-03 6.980028e-02 9 137096240 137096391 152 + 1.751 1.630 -0.411
ENSG00000177239 E029 20.0755797 0.0006792669 2.396838e-04 4.854026e-03 9 137097828 137097859 32 + 1.439 1.202 -0.828
ENSG00000177239 E030 28.7127266 0.0011072131 8.381598e-03 7.134677e-02 9 137097860 137097937 78 + 1.546 1.400 -0.500
ENSG00000177239 E031 52.6458679 0.0059537119 4.090295e-02 1.962692e-01 9 137099696 137099881 186 + 1.780 1.679 -0.342
ENSG00000177239 E032 2.1074476 0.0488792083 4.831774e-01 7.478771e-01 9 137099882 137101004 1123 + 0.421 0.533 0.559
ENSG00000177239 E033 62.4618645 0.0002629340 4.750370e-07 2.363528e-05 9 137101005 137101153 149 + 1.895 1.708 -0.632
ENSG00000177239 E034 75.1593234 0.0002171215 1.532921e-07 8.549800e-06 9 137101484 137101672 189 + 1.970 1.792 -0.597
ENSG00000177239 E035 11.0215284 0.0017837982 9.877185e-07 4.612261e-05 9 137101673 137102144 472 + 0.751 1.220 1.747
ENSG00000177239 E036 16.0658713 0.0059056557 1.733480e-04 3.723357e-03 9 137102145 137102665 521 + 1.024 1.335 1.110
ENSG00000177239 E037 2.9572391 0.0049336144 7.874654e-01 9.185138e-01 9 137102666 137102711 46 + 0.572 0.610 0.170
ENSG00000177239 E038 7.1108237 0.0019516534 2.068967e-03 2.621457e-02 9 137102712 137102901 190 + 0.683 1.018 1.304
ENSG00000177239 E039 5.8777028 0.0111370335 1.664545e-03 2.214828e-02 9 137102902 137103057 156 + 0.572 0.960 1.572
ENSG00000177239 E040 2.3588189 0.0211884960 2.784997e-01 5.717342e-01 9 137103058 137103094 37 + 0.421 0.586 0.800
ENSG00000177239 E041 10.3913548 0.0014880633 1.779073e-06 7.684207e-05 9 137103095 137103347 253 + 0.730 1.196 1.751
ENSG00000177239 E042 16.4981835 0.0011927013 3.447525e-08 2.208300e-06 9 137103348 137103868 521 + 0.937 1.377 1.578
ENSG00000177239 E043 18.9566333 0.0008404962 1.199245e-13 1.772056e-11 9 137103869 137104329 461 + 0.878 1.460 2.088
ENSG00000177239 E044 4.3793131 0.0035537984 2.703582e-03 3.190002e-02 9 137104330 137104425 96 + 0.464 0.854 1.685
ENSG00000177239 E045 7.4245534 0.0022752102 7.998139e-08 4.756027e-06 9 137104426 137104602 177 + 0.464 1.094 2.578
ENSG00000177239 E046 8.5184637 0.0639912476 1.009125e-03 1.510954e-02 9 137104603 137104863 261 + 0.631 1.123 1.907
ENSG00000177239 E047 5.5113631 0.0438813129 2.279381e-03 2.817698e-02 9 137104864 137105011 148 + 0.503 0.949 1.855
ENSG00000177239 E048 15.6042074 0.0009541682 9.556939e-07 4.486022e-05 9 137105012 137105424 413 + 0.950 1.344 1.412
ENSG00000177239 E049 9.2886719 0.0048810085 6.261344e-07 3.047828e-05 9 137105425 137105607 183 + 0.631 1.164 2.054
ENSG00000177239 E050 10.7520078 0.0206342098 2.599992e-04 5.183335e-03 9 137105608 137105829 222 + 0.792 1.196 1.503
ENSG00000177239 E051 4.8810054 0.0046242476 2.104856e-03 2.656759e-02 9 137105830 137105916 87 + 0.503 0.892 1.639
ENSG00000177239 E052 8.9811524 0.0018516566 7.328069e-04 1.176987e-02 9 137105917 137106124 208 + 0.772 1.109 1.270
ENSG00000177239 E053 21.9680422 0.0006351979 4.735719e-03 4.765071e-02 9 137106125 137106127 3 + 1.448 1.274 -0.605
ENSG00000177239 E054 73.4126055 0.0002227495 6.164376e-04 1.024148e-02 9 137106128 137106315 188 + 1.930 1.813 -0.392
ENSG00000177239 E055 5.5993499 0.0280125803 6.183735e-02 2.498117e-01 9 137106316 137106688 373 + 0.658 0.904 0.984
ENSG00000177239 E056 57.0042011 0.0002414899 6.914807e-02 2.656858e-01 9 137106689 137106809 121 + 1.797 1.728 -0.235
ENSG00000177239 E057 0.8814907 0.0166533343 9.355359e-02 3.180810e-01 9 137106810 137107132 323 + 0.105 0.365 2.270
ENSG00000177239 E058 0.3714026 0.0166013598 7.315925e-01   9 137107133 137107249 117 + 0.105 0.158 0.685
ENSG00000177239 E059 24.9224198 0.0074636905 4.835260e-01 7.480063e-01 9 137107250 137107274 25 + 1.435 1.389 -0.159
ENSG00000177239 E060 47.9609047 0.0003664690 9.404323e-01 9.830569e-01 9 137107275 137107357 83 + 1.686 1.685 -0.003
ENSG00000177239 E061 61.4247012 0.0002306176 5.419264e-01 7.893578e-01 9 137107358 137107447 90 + 1.776 1.802 0.086
ENSG00000177239 E062 0.4890306 0.0890316518 8.373873e-01   9 137107448 137107530 83 + 0.189 0.158 -0.315
ENSG00000177239 E063 27.2427416 0.0008357068 3.338459e-01 6.257940e-01 9 137107531 137107534 4 + 1.412 1.470 0.199
ENSG00000177239 E064 27.9431798 0.0016327385 7.079672e-01 8.815510e-01 9 137107535 137107537 3 + 1.443 1.467 0.081
ENSG00000177239 E065 27.8529327 0.0005295300 3.911005e-01 6.763722e-01 9 137107538 137107541 4 + 1.426 1.477 0.174
ENSG00000177239 E066 82.5994122 0.0001862111 4.716927e-01 7.390578e-01 9 137107542 137107662 121 + 1.903 1.928 0.087
ENSG00000177239 E067 15.0702950 0.0017370778 6.053350e-05 1.556891e-03 9 137107663 137108211 549 + 0.988 1.312 1.160
ENSG00000177239 E068 8.4864519 0.0019732189 1.040239e-03 1.544721e-02 9 137108212 137108387 176 + 0.751 1.086 1.270
ENSG00000177239 E069 54.3996594 0.0003832485 6.768751e-01 8.660289e-01 9 137108388 137108426 39 + 1.728 1.747 0.065
ENSG00000177239 E070 93.5175386 0.0001735667 6.741541e-01 8.649688e-01 9 137108427 137108530 104 + 1.962 1.977 0.051
ENSG00000177239 E071 260.7645879 0.0007815914 3.888624e-01 6.747604e-01 9 137108531 137109215 685 + 2.422 2.407 -0.051

Help

Please Click HERE to learn more details about the results from DEXseq.