ENSG00000177463

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000393102 ENSG00000177463 No_inf pgKDN_inf NR2C2 protein_coding protein_coding 8.409759 10.88348 7.379603 1.342766 0.5279987 -0.5598968 0.6220185 0.6139720 1.2520834 0.6139720 0.9492893 1.0162540 0.07129167 0.059575 0.154300 0.094725 0.79839106 0.03189584 FALSE TRUE
ENST00000406272 ENSG00000177463 No_inf pgKDN_inf NR2C2 protein_coding protein_coding 8.409759 10.88348 7.379603 1.342766 0.5279987 -0.5598968 1.3187091 0.0000000 2.8786746 0.0000000 1.1343902 8.1742639 0.18200833 0.000000 0.427650 0.427650 0.03189584 0.03189584 FALSE TRUE
ENST00000413118 ENSG00000177463 No_inf pgKDN_inf NR2C2 protein_coding protein_coding 8.409759 10.88348 7.379603 1.342766 0.5279987 -0.5598968 0.2879635 0.8638906 0.0000000 0.8638906 0.0000000 -6.4493808 0.01943333 0.058300 0.000000 -0.058300 0.87651499 0.03189584 FALSE FALSE
ENST00000413194 ENSG00000177463 No_inf pgKDN_inf NR2C2 protein_coding protein_coding 8.409759 10.88348 7.379603 1.342766 0.5279987 -0.5598968 0.4302622 1.0647047 0.2260819 0.6427404 0.2260819 -2.1865812 0.04232500 0.096300 0.030675 -0.065625 0.83741621 0.03189584 FALSE TRUE
ENST00000425241 ENSG00000177463 No_inf pgKDN_inf NR2C2 protein_coding protein_coding 8.409759 10.88348 7.379603 1.342766 0.5279987 -0.5598968 0.9973363 1.1097032 0.6107192 0.7837690 0.6107192 -0.8511036 0.12718333 0.122650 0.077150 -0.045500 0.86112554 0.03189584 FALSE TRUE
ENST00000439011 ENSG00000177463 No_inf pgKDN_inf NR2C2 protein_coding protein_coding 8.409759 10.88348 7.379603 1.342766 0.5279987 -0.5598968 0.5606187 0.3231027 0.3566492 0.3231027 0.2174867 0.1384334 0.06650000 0.031350 0.050875 0.019525 0.83037221 0.03189584 FALSE TRUE
ENST00000475707 ENSG00000177463 No_inf pgKDN_inf NR2C2 protein_coding retained_intron 8.409759 10.88348 7.379603 1.342766 0.5279987 -0.5598968 0.5422630 0.8896136 0.3870057 0.1769299 0.1258915 -1.1801458 0.06134167 0.082525 0.050975 -0.031550 0.85314455 0.03189584 TRUE TRUE
ENST00000478572 ENSG00000177463 No_inf pgKDN_inf NR2C2 protein_coding protein_coding_CDS_not_defined 8.409759 10.88348 7.379603 1.342766 0.5279987 -0.5598968 1.0094305 1.5372262 0.5355995 0.2942593 0.1955605 -1.5037698 0.11714167 0.139275 0.068750 -0.070525 0.66988073 0.03189584 FALSE TRUE
ENST00000495282 ENSG00000177463 No_inf pgKDN_inf NR2C2 protein_coding retained_intron 8.409759 10.88348 7.379603 1.342766 0.5279987 -0.5598968 0.4290604 0.9946202 0.1520795 0.2636984 0.1520795 -2.6318769 0.04219167 0.088750 0.020625 -0.068125 0.41697909 0.03189584   FALSE
ENST00000617312 ENSG00000177463 No_inf pgKDN_inf NR2C2 protein_coding protein_coding 8.409759 10.88348 7.379603 1.342766 0.5279987 -0.5598968 0.3082501 0.9247503 0.0000000 0.9247503 0.0000000 -6.5465092 0.02080000 0.062400 0.000000 -0.062400 0.87704044 0.03189584 FALSE TRUE
MSTRG.19772.7 ENSG00000177463 No_inf pgKDN_inf NR2C2 protein_coding   8.409759 10.88348 7.379603 1.342766 0.5279987 -0.5598968 1.0282616 1.4729472 0.0000000 0.8644397 0.0000000 -7.2123234 0.15473333 0.159525 0.000000 -0.159525 0.62074629 0.03189584 FALSE TRUE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000177463 E001 0.1187032 0.011992953 0.337810580   3 14947583 14947583 1 + 0.115 0.000 -10.754
ENSG00000177463 E002 0.4913966 0.029158187 0.659591011   3 14947584 14947704 121 + 0.205 0.145 -0.609
ENSG00000177463 E003 0.1187032 0.011992953 0.337810580   3 14947705 14947728 24 + 0.115 0.000 -12.804
ENSG00000177463 E004 0.0000000       3 14947729 14947839 111 +      
ENSG00000177463 E005 0.0000000       3 14947840 14947906 67 +      
ENSG00000177463 E006 0.0000000       3 14948632 14948725 94 +      
ENSG00000177463 E007 0.0000000       3 14948726 14948727 2 +      
ENSG00000177463 E008 0.2444846 0.016424947 0.726132065   3 14959157 14959196 40 + 0.115 0.079 -0.609
ENSG00000177463 E009 0.6063816 0.016546092 0.347547881 0.63818083 3 14959536 14959641 106 + 0.280 0.145 -1.194
ENSG00000177463 E010 0.0000000       3 14962407 14962408 2 +      
ENSG00000177463 E011 0.4795276 0.019310690 0.151178507   3 14962409 14962492 84 + 0.280 0.079 -2.194
ENSG00000177463 E012 1.1252191 0.014555004 0.286849130 0.58025900 3 15003876 15003914 39 + 0.205 0.378 1.198
ENSG00000177463 E013 1.8962846 0.010251822 0.004077862 0.04300654 3 15003915 15003986 72 + 0.115 0.577 3.198
ENSG00000177463 E014 1.1425942 0.011526742 0.006701935 0.06120254 3 15004557 15004613 57 + 0.000 0.445 13.954
ENSG00000177463 E015 0.0000000       3 15013589 15013740 152 +      
ENSG00000177463 E016 0.0000000       3 15013741 15013789 49 +      
ENSG00000177463 E017 2.7225145 0.005540737 0.798936892 0.92449661 3 15016152 15016254 103 + 0.534 0.577 0.198
ENSG00000177463 E018 5.5268681 0.003291532 0.279664273 0.57292562 3 15020753 15020932 180 + 0.866 0.760 -0.417
ENSG00000177463 E019 0.0000000       3 15020933 15020935 3 +      
ENSG00000177463 E020 0.0000000       3 15023200 15023347 148 +      
ENSG00000177463 E021 0.0000000       3 15024115 15024208 94 +      
ENSG00000177463 E022 8.2560743 0.002012384 0.001131580 0.01647207 3 15025565 15027009 1445 + 0.719 1.053 1.284
ENSG00000177463 E023 5.1188656 0.003059678 0.014834120 0.10428355 3 15028586 15028719 134 + 0.917 0.660 -1.024
ENSG00000177463 E024 7.3557444 0.017065670 0.154920732 0.42052920 3 15030275 15030452 178 + 0.990 0.854 -0.513
ENSG00000177463 E025 3.5631160 0.004178281 0.518621018 0.77356836 3 15032379 15032426 48 + 0.693 0.620 -0.310
ENSG00000177463 E026 3.9169949 0.003870337 0.201553447 0.48395439 3 15032427 15032500 74 + 0.766 0.620 -0.609
ENSG00000177463 E027 1.0056079 0.011879866 0.099873603 0.33017939 3 15034324 15034652 329 + 0.115 0.378 2.198
ENSG00000177463 E028 0.2438580 0.016682364 0.725144473   3 15034653 15034669 17 + 0.115 0.079 -0.609
ENSG00000177463 E029 5.9160586 0.019291918 0.726763574 0.89074575 3 15034670 15034809 140 + 0.848 0.816 -0.124
ENSG00000177463 E030 6.0491959 0.002790697 0.963737966 0.99234787 3 15038000 15038137 138 + 0.829 0.842 0.050
ENSG00000177463 E031 3.5913495 0.004685176 0.605029602 0.82782146 3 15038138 15039121 984 + 0.605 0.678 0.317
ENSG00000177463 E032 3.2127052 0.027301042 0.960776689 0.99122352 3 15039122 15039227 106 + 0.605 0.620 0.069
ENSG00000177463 E033 0.0000000       3 15042834 15049273 6440 +      
ENSG00000177463 E034 0.0000000       3 15053361 15053450 90 +      
ENSG00000177463 E035 0.8774954 0.056992165 0.167170441 0.43771393 3 15053451 15053600 150 + 0.115 0.340 1.976

Help

Please Click HERE to learn more details about the results from DEXseq.