ENSG00000177706

1 Isoform Switch

Summary Plot

Only the isoforms with fraction > 5% are shown below.

  • Note:

    • About the Coding Potential: Please check the spreadsheet in the “Results” tag to confirm the coding potential. The above figure only show the predicted coding potential. The “gene_biotype” in the result spreadsheet is from the database record. Therefore, if you find conflicts between “gene_biotype” and “codingPotential”, please trust the “gene_biotype”.

    • Notes on IDR and IDR_w_binding: As the prediction of Intrinsically Disordered Regions (IDR) and Intrinsically Disordered Binding Regions (IDBR) are done by two different tools we require two things to annotate the Intrinsically Disordered Binding Regions (IDBR). Firstly the IDBR (predicted by ANCHOR2) must be a region of at least 15 amino acids (after the smoothing). Secondly the fraction of the IDBR which overlaps the IDR predictions (done by IUPred3, again after smoothing) must be at least 80%. When that is the case the IDR type will be annotated as “IDR_w_binding_region” instead of just “IDR”. The current default parameters have not been rigorously tested and should be considered experimental.

    • For the function of any other domain, please Click HERE to search it through Pfam database.

Results

isoform_id gene_id condition_1 condition_2 gene_name gene_biotype iso_biotype gene_overall_mean gene_value_1 gene_value_2 gene_stderr_1 gene_stderr_2 gene_log2_fold_change iso_overall_mean iso_value_1 iso_value_2 iso_stderr_1 iso_stderr_2 iso_log2_fold_change IF_overall IF1 IF2 dIF isoform_switch_q_value gene_switch_q_value PTC codingPotential
ENST00000313766 ENSG00000177706 No_inf pgKDN_inf FAM20C protein_coding protein_coding 112.4036 115.106 112.5255 1.613687 1.789606 -0.0327092 46.69328 46.635058 48.42197 1.9670800 1.3247940 0.05423553 0.4158583 0.405275 0.431150 0.025875 8.531446e-01 2.198499e-06 FALSE TRUE
ENST00000471328 ENSG00000177706 No_inf pgKDN_inf FAM20C protein_coding protein_coding_CDS_not_defined 112.4036 115.106 112.5255 1.613687 1.789606 -0.0327092 18.72894 7.227603 25.52248 0.9496037 0.1797183 1.81874996 0.1680583 0.062925 0.226925 0.164000 2.198499e-06 2.198499e-06 FALSE FALSE
MSTRG.25709.7 ENSG00000177706 No_inf pgKDN_inf FAM20C protein_coding   112.4036 115.106 112.5255 1.613687 1.789606 -0.0327092 42.95172 58.453103 34.77867 2.4406405 3.1489781 -0.74890893 0.3800833 0.507575 0.308025 -0.199550 1.115881e-03 2.198499e-06 FALSE FALSE
  • Note:
    • The comparisons made can be identified as “from ‘condition_1’ to ‘condition_2’”, meaning ‘condition_1’ is considered the ground state and ‘condition_2’ the changed state. This also means that a positive dIF value indicates that the isoform usage is increased in ‘condition_2’ compared to ‘condition_1’. Since the ‘isoformFeatures’ entry is the most relevant part of the switchAnalyzeRlist object, the most-used standard methods have also been implemented to work directly on isoformFeatures.

Help

Please Click HERE to learn more details about the results of IsoformSwitchAnalyzeR.

2 Differential Exon Usage

Counts

All exons whithin this gene region are shown and numbering below.

Expression

All exons whithin this gene region are shown and numbering below.

Splicing

All exons whithin this gene region are shown and numbering below.

Transcripts

All isoforms whithin this gene region are shown below.

Results

groupID featureID exonBaseMean dispersion pvalue padj seqnames start end width strand pgKDN.inf No.inf log2fold_No.inf_pgKDN.inf
ENSG00000177706 E001 1.234451 1.062813e-02 5.182709e-01 7.734647e-01 7 192456 192475 20 + 0.295 0.394 0.599
ENSG00000177706 E002 1.460526 9.260936e-03 5.820971e-01 8.138723e-01 7 192476 192570 95 + 0.432 0.348 -0.471
ENSG00000177706 E003 216.988722 1.039355e-04 1.175662e-02 8.942058e-02 7 192571 193804 1234 + 2.363 2.313 -0.168
ENSG00000177706 E004 0.000000       7 195242 195327 86 +      
ENSG00000177706 E005 61.245550 2.390282e-04 6.002698e-03 5.648371e-02 7 195554 195624 71 + 1.737 1.841 0.352
ENSG00000177706 E006 81.135583 1.813512e-04 7.684620e-02 2.834706e-01 7 195625 195732 108 + 1.884 1.941 0.194
ENSG00000177706 E007 2.374005 1.731325e-02 1.960067e-05 6.075532e-04 7 197130 197132 3 + 0.750 0.096 -4.234
ENSG00000177706 E008 338.745273 7.126885e-05 3.515057e-187 9.479055e-183 7 197133 200794 3662 + 2.712 2.243 -1.563
ENSG00000177706 E009 66.755903 2.383646e-04 1.081082e-01 3.447893e-01 7 208898 208976 79 + 1.800 1.858 0.195
ENSG00000177706 E010 0.126854 1.230875e-02 5.316579e-01   7 245895 246414 520 + 0.000 0.096 9.461
ENSG00000177706 E011 63.672375 4.746601e-03 1.328912e-03 1.866012e-02 7 246415 246507 93 + 1.727 1.877 0.505
ENSG00000177706 E012 65.549914 1.113521e-03 6.189140e-03 5.774176e-02 7 248315 248430 116 + 1.765 1.871 0.357
ENSG00000177706 E013 0.371400 1.650388e-02 5.762819e-01   7 252611 252643 33 + 0.095 0.174 1.015
ENSG00000177706 E014 105.714634 1.717679e-04 3.209151e-07 1.670679e-05 7 255849 256029 181 + 1.945 2.093 0.496
ENSG00000177706 E015 2.002180 6.920132e-03 9.661886e-03 7.859243e-02 7 256195 256653 459 + 0.238 0.623 2.130
ENSG00000177706 E016 76.286053 2.354706e-03 3.710092e-03 4.031102e-02 7 256654 256763 110 + 1.826 1.939 0.379
ENSG00000177706 E017 68.868862 2.459499e-04 1.441732e-01 4.043512e-01 7 257005 257086 82 + 1.816 1.868 0.174
ENSG00000177706 E018 1.896472 8.842638e-03 2.786572e-04 5.471094e-03 7 257087 257453 367 + 0.095 0.648 3.822
ENSG00000177706 E019 56.620450 3.004506e-04 3.360081e-03 3.760586e-02 7 258646 258705 60 + 1.696 1.813 0.393
ENSG00000177706 E020 516.352030 7.271259e-05 2.841554e-53 5.894476e-50 7 259731 260772 1042 + 2.613 2.791 0.593

Help

Please Click HERE to learn more details about the results from DEXseq.